Publications

Checco JW, Gellman SH. Iterative Nonproteinogenic Residue Incorporation Yields alpha/beta-Peptides with a Helix-Loop-Helix Tertiary Structure and High Affinity for VEGF. Chembiochem. 2017;18:291-299.
Choi H, Chakraborty S, Liu RH, Gellman SH, Weisshaar JC. Single-Cell, Time-Resolved Antimicrobial Effects of a Highly Cationic, Random Nylon-3 Copolymer on Live Escherichia coli. ACSChemical Biology. 2016;11:113-120.
Walsh PS, Dean JC, McBurney C, Kang H, Gellman SH, Zwier TS. Conformation-specific spectroscopy of capped glutamine-containing peptides: role of a single glutamine residue on peptide backbone preferences. Physical Chemistry Chemical Physics. 2016;18:11306-11322.
Kreitler DF, Mortenson DE, Forest KT, Gellman SH. Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization. Journal of the American Chemical Society. 2016;138:6498-6505.
MacDonald MJ, Lavis LD, Hilvert D, Gellman SH. Evaluation of the Ser-His Dipeptide, a Putative Catalyst of Amide and Ester Hydrolysis. Organic Letters. 2016;18:3518-3521.
Checco JW, Gellman SH. Targeting recognition surfaces on natural proteins with peptidic foldamers. Current Opinion in Structural Biology. 2016;39:96-105.
Hager MV, Johnson LM, Wootten D, Sexton PM, Gellman SH. beta-Arrestin-Biased Agonists of the GLP-1 Receptor from beta-Amino Acid Residue Incorporation into GLP-1 Analogues. Journal of the American Chemical Society. 2016;138:14970-14979.
Nadithe V, Liu RH, Killinger BA, Movassaghian S, Kim NH, Moszczynska AB, et al.. Screening Nylon-3 Polymers, a New Class of Cationic Amphiphiles, for siRNA Delivery. Mol Pharm. 2015;12:362-374.
Liu RH, Chen XY, Falk SP, Masters KS, Weisblum B, Gellman SH. Nylon-3 Polymers Active against Drug-Resistant Candida albicans Biofilms. Journal of the American Chemical Society. 2015;137:2183-2186.
Cheloha RW, Sullivan JA, Wang T, Sand JM, Sidney J, Sette A, et al.. Consequences of Periodic alpha-to-beta(3) Residue Replacement for Immunological Recognition of Peptide Epitopes. ACS Chemical Biology. 2015;10:844-854.
Fisher BF, Guo L, Dolinar BS, Guzei IA, Gellman SH. Heterogeneous H-Bonding in a Foldamer Helix. Journal of the American Chemical Society. 2015;137:6484-6487.
Demizu Y, Oba M, Okitsu K, Yamashita H, Misawa T, Tanaka M, et al.. A preorganized beta-amino acid bearing a guanidinium side chain and its use in cell-penetrating peptides. Organic & Biomolecular Chemistry. 2015;13:5617-5620.
Checco JW, Kreitler DF, Thomas NC, Belair DG, Rettko NJ, Murphy WL, et al.. Targeting diverse protein-protein interaction interfaces with alpha/beta-peptides derived from the Z-domain scaffold. Proceedings of the National Academy of Sciences of the United States of America. 2015;112:4552-4557.
Hovakeemian SG, Liu RH, Gellman SH, Heerklotz H. Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents. Soft Matter. 2015;11:6840-6851.
Checco JW, Lee EF, Evangelista M, Sleebs NJ, Rogers K, Pettikiriarachchi A, et al.. alpha/beta-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells. Journal of the American Chemical Society. 2015;137:11365-11375.
Mortenson DE, Steinkruger JD, Kreitler DF, Perroni DV, Sorenson GP, Huang L, et al.. High-resolution structures of a heterochiral coiled coil. Proceedings of the National Academy of Sciences of the United States of America. 2015;112:13144-13149.
Cheloha RW, Gellman SH, Vilardaga JP, Gardella TJ. PTH receptor-1 signalling-mechanistic insights and therapeutic prospects. Nature Reviews Endocrinology. 2015;11:712-724.
Kung VM, Cornilescu G, Gellman SH. Impact of Strand Number on Parallel beta-Sheet Stability. Angewandte Chemie-International Edition. 2015;54:14336-14339.
Hayouka Z, Thomas NC, Mortenson DE, Satyshur KA, Weisblum B, Forest KT, et al.. Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif. Journal of the American Chemical Society. 2015;137:11884-7.
Ma CD, Wang CX, Acevedo-Velez C, Gellman SH, Abbott NL. Modulation of hydrophobic interactions by proximally immobilized ions. Nature. 2015;517:347-U443.
Liu RH, Chen XY, Chakraborty S, Lemke JJ, Hayouka Z, Chow C, et al.. Tuning the Biological Activity Profile of Antibacterial Polymers via Subunit Substitution Pattern. Journal of the American Chemical Society. 2014;136:4410-4418.
Laaser JE, Skoff DR, Ho JJ, Joo Y, Serrano AL, Steinkruger JD, et al.. Two-Dimensional Sum-Frequency Generation Reveals Structure and Dynamics of a Surface-Bound Peptide. Journal of the American Chemical Society. 2014;136:956-962.
Mayer C, Muller MM, Gellman SH, Hilvert D. Building Proficient Enzymes with Foldamer Prostheses. Angewandte Chemie-International Edition. 2014;53:6978-6981.
Lee MR, Raman N, Gellman SH, Lynn DM, Palecek SP. Hydrophobicity and Helicity Regulate the Antifungal Activity of 14-Helical beta-Peptides. ACS Chemical Biology. 2014;9:1613-1621.
Lee MW, Chakraborty S, Schmidt NW, Murgai R, Gellman SH, Wong GCL. Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides. Biochimica Et Biophysica Acta-Biomembranes. 2014;1838:2269-2279.
Gord JR, Walsh PS, Fisher BF, Gellman SH, Zwier TS. Mimicking the First Turn of an alpha-Helix with an Unnatural Backbone: Conformation-Specific IR and UV Spectroscopy of Cyclically Constrained beta/gamma-Peptides. Journal of Physical Chemistry B. 2014;118:8246-8256.
Stephenson NA, Gellman SH, Stahl SS. Ammonolysis of anilides promoted by ethylene glycol and phosphoric acid. Rsc Advances. 2014;4:46840-46843.
Liu RH, Suarez JM, Weisblum B, Gellman SH, McBride SM. Synthetic Polymers Active against Clostridium difficile Vegetative Cell Growth and Spore Outgrowth. Journal of the American Chemical Society. 2014;136:14498-14504.
Chakraborty S, Liu RH, Hayouka Z, Chen XY, Ehrhardt J, Lu Q, et al.. Ternary Nylon-3 Copolymers as Host-Defense Peptide Mimics: Beyond Hydrophobic and Cationic Subunits. Journal of the American Chemical Society. 2014;136:14530-14535.
Maynard SJ, Almeida AM, Yoshimi Y, Gellman SH. New Charge-Bearing Amino Acid Residues That Promote beta-Sheet Secondary Structure. Journal of the American Chemical Society. 2014;136:16683-16688.
Liu RH, Chen XY, Falk SP, Mowery BP, Karlsson AJ, Weisblum B, et al.. Structure-Activity Relationships among Antifungal Nylon-3 Polymers: Identification of Materials Active against Drug-Resistant Strains of Candida albicans. Journal of the American Chemical Society. 2014;136:4333-4342.
Cho KH, Bae HE, Das M, Gellman SH, Chae PS. Improved Glucose-Neopentyl Glycol (GNG) Amphiphiles for Membrane Protein Solubilization and Stabilization. Chemistry-an Asian Journal. 2014;9:632-638.
Chae PS, Sadaf A, Gellman SH. Hydrophobic Variations of N-Oxide Amphiphiles for Membrane Protein Manipulation: Importance of Non-hydrocarbon Groups in the Hydrophobic Portion. Chemistry-an Asian Journal. 2014;9:110-116.
Chae PS, Cho KH, Wander MJ, Bae HE, Gellman SH, Laible PD. Hydrophobic variants of ganglio-tripod amphiphiles for membrane protein manipulation. Biochimica Et Biophysica Acta-Biomembranes. 2014;1838:278-286.
Cheloha RW, Maeda A, Dean T, Gardella TJ, Gellman SH. Backbone modification of a polypeptide drug alters duration of action in vivo. Nature Biotechnology. 2014;32:653-+.
Johnson LM, Barrick S, Hager MV, McFedries A, Homan EA, Rabaglia ME, et al.. A Potent alpha/beta-Peptide Analogue of GLP-1 with Prolonged Action in Vivo. Journal of the American Chemical Society. 2014;136:12848-12851.
Giuliano MW, Maynard SJ, Almeida AM, Guo L, Guzei IA, Spencer LC, et al.. A gamma-Amino Acid That Favors 12/10-Helical Secondary Structure in alpha/gamma-Peptides. Journal of the American Chemical Society. 2014;136:15046-15053.
Johnson LM, Gellman SH. alpha-Helix Mimicry with alpha/beta-Peptides. In: Keating AE. 2013. pp. 407-429.
Shin YH, Mortenson DE, Satyshur KA, Forest KT, Gellman SH. Differential Impact of beta and gamma Residue Preorganization on alpha/beta/gamma-Peptide Helix Stability in Water. Journal of the American Chemical Society. 2013;135:8149-8152.
Mortenson DE, Kreitler DF, Yun HG, Gellman SH, Forest KT. Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain. Acta Crystallographica Section D-Biological Crystallography. 2013;69:2506-2512.
Liu RH, Chen XY, Hayouka Z, Chakraborty S, Falk SP, Weisblum B, et al.. Nylon-3 Polymers with Selective Antifungal Activity. Journal of the American Chemical Society. 2013;135:5270-5273.
Liu RH, Chen XY, Gellman SH, Masters KS. Nylon-3 Polymers That Enable Selective Culture of Endothelial Cells. Journal of the American Chemical Society. 2013;135:16296-16299.
Kusaka R, Zhang D, Walsh PS, Gord JR, Fisher BF, Gellman SH, et al.. Role of Ring-Constrained gamma-Amino Acid Residues in alpha/gamma-Peptide Folding: Single-Conformation UV and IR Spectroscopy. Journal of Physical Chemistry A. 2013;117:10847-10862.
Arnold U, Huck BR, Gellman SH, Raines RT. Protein prosthesis: beta-peptides as reverse-turn surrogates. Protein Science. 2013;22:274-279.
Smith BJ, Lee EF, Checco JW, Evangelista M, Gellman SH, Fairlie DW. Structure-Guided Rational Design of α/β-Peptide Foldamers with High Affinity for BCL-2 Family Prosurvival Proteins. Chembiochem. 2013;14:1564-1572.
Hayouka Z, Mortenson DE, Kreitler DF, Weisblum B, Forest KT, Gellman SH. Evidence for Phenylalanine Zipper-Mediated Dimerization in the X-ray Crystal Structure of a Magainin 2 Analogue. Journal of the American Chemical Society. 2013;135:15738-15741.
Hayouka Z, Chakraborty S, Liu RH, Boersma MD, Weisblum B, Gellman SH. Interplay among Subunit Identity, Subunit Proportion, Chain Length, and Stereochemistry in the Activity Profile of Sequence-Random Peptide Mixtures. Journal of the American Chemical Society. 2013;135:11748-11751.
Giuliano MW, Maynard SJ, Almeida AM, Reidenbach AG, Guo L, Ulrich EC, et al.. Evaluation of a Cyclopentane-Based gamma-Amino Acid for the Ability to Promote alpha/gamma-Peptide Secondary Structure. Journal of Organic Chemistry. 2013;78:12351-12361.
Choi SH, Ivancic M, Guzei IA, Gellman SH. Structural Characterization of Peptide Oligomers Containing (1R,2S)-2-Aminocyclohexanecarboxylic Acid (cis-ACHC). European Journal of Organic Chemistry. 2013;:3464-3469.
Chakraborty S, Liu RH, Lemke JJ, Hayouka Z, Welch RA, Weisblum B, et al.. Effects of Cyclic vs Acyclic Hydrophobic Subunits on the Chemical Structure and Biological Properties of Nylon-3 Copolymers. Acs Macro Letters. 2013;2:753-756.
Chae PS, Wander MJ, Cho KH, Laible PD, Gellman SH. Carbohydrate-containing Triton X-100 analogues for membrane protein solubilization and stabilization. Molecular Biosystems. 2013;9:626-629.
Chae PS, Rana RR, Gotfryd K, Rasmussen SGF, Kruse AC, Cho KH, et al.. Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study. Chemical Communications. 2013;49:2287-2289.
Chae PS, Kruse AC, Gotfryd K, Rana RR, Cho KH, Rasmussen SGF, et al.. Novel Tripod Amphiphiles for Membrane Protein Analysis. Chemistry-A European Journal. 2013;19:15645-15651.
Zhang JH, Markiewicz MJ, Weisblum B, Stahl SS, Gellman SH. Functionally Diverse Nylon-3 Copolymers from Readily Accessible beta-Lactams. Acs Macro Letters. 2012;1:714-717.
Zhang J, Markiewicz MJ, Mowery BP, Weisblurn B, Stahl SS, Gellman SH. C-Terminal Functionalization of Nylon-3 Polymers: Effects of C-Terminal Groups on Antibacterial and Hemolytic Activities. Biomacromolecules. 2012;13:323-331.
Woys AM, Almeida AM, Wang L, Chiu CC, McGovern M, de Pablo JJ, et al.. Parallel beta-Sheet Vibrational Couplings Revealed by 2D IR Spectroscopy of an Isotopically Labeled Macrocycle: Quantitative Benchmark for the Interpretation of Amyloid and Protein Infrared Spectra. Journal of the American Chemical Society. 2012;134:19118-19128.
Steinkruger JD, Bartlett GJ, Woolfson DN, Gellman SH. Strong Contributions from Vertical Triads to Helix-Partner Preferences in Parallel Coiled Coils. Journal of the American Chemical Society. 2012;134:15652-15655.
Steinkruger JD, Bartlett GJ, Hadley EB, Fay L, Woolfson DN, Gellman SH. The d '-d-d ' Vertical Triad Is Less Discriminating Than the a '-a-a ' Vertical Triad in the Antiparallel Coiled-Coil Dimer Motif. Journal of the American Chemical Society. 2012;134:2626-2633.
Mortenson DE, Satyshur KA, Guzei IA, Forest KT, Gellman SH. Quasiracemic Crystallization as a Tool To Assess the Accommodation of Noncanonical Residues in Nativelike Protein Conformations. Journal of the American Chemical Society. 2012;134:2473-2476.
Liu RH, Vang KZ, Kreeger PK, Gellman SH, Masters KS. Experimental and computational analysis of cellular interactions with nylon-3-bearing substrates. Journal of Biomedical Materials Research Part A. 2012;100A:2750-2759.
Liu RH, Masters KS, Gellman SH. Polymer Chain Length Effects on Fibroblast Attachment on Nylon-3-Modified Surfaces. Biomacromolecules. 2012;13:1100-1105.
Johnson LM, Mortenson DE, Yun HG, Horne WS, Ketas TJ, Lu M, et al.. Enhancement of alpha-Helix Mimicry by an alpha/beta-Peptide Foldamer via Incorporation of a Dense Ionic Side-Chain Array. Journal of the American Chemical Society. 2012;134:7317-7320.
Haase HS, Peterson-Kaufman KJ, Levengood SKL, Checco JW, Murphy WL, Gellman SH. Extending Foldamer Design beyond alpha-Helix Mimicry: alpha/beta-Peptide Inhibitors of Vascular Endothelial Growth Factor Signaling. Journal of the American Chemical Society. 2012;134:7652-7655.
Guo L, Zhang WC, Guzei IA, Spencer LC, Gellman SH. Helical secondary structures in 2:1 and 1:2 alpha/gamma-peptide foldamers. Tetrahedron. 2012;68:4413-4417.
Guo L, Zhang WC, Guzei IA, Spencer LC, Gellman SH. New Preorganized gamma-Amino Acids as Foldamer Building Blocks. Organic Letters. 2012;14:2582-2585.
Gellman SH. Biologically active nylon-3 copolymers. Polymer Preprints. 2012;53:366-367.
Chae PS, Rasmussen SGF, Rana RR, Gotfryd K, Kruse AC, Manglik A, et al.. A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins. Chemistry-A European Journal. 2012;18:9485-9490, S9485/1-S9485/25.
Buchanan EG, James, William H. III, Choi SH, Guo L, Gellman SH, Mueller CW, et al.. Single-conformation infrared spectra of model peptides in the amide I and amide II regions: Experiment-based determination of local mode frequencies and inter-mode coupling. Journal of Chemical Physics. 2012;137:094301/1-094301/16.
Boersma MD, Haase HS, Peterson-Kaufman KJ, Lee EF, Clarke OB, Colman PM, et al.. Evaluation of Diverse α/β-Backbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 Domain. Journal of the American Chemical Society. 2012;134:315-323.
Almeida AM, Li R, Gellman SH. Parallel β-Sheet Secondary Structure Is Stabilized and Terminated by Interstrand Disulfide Cross-Linking. Journal of the American Chemical Society. 2012;134:75-78.
Selao TT, Branca R, Chae PS, Lehtio J, Gellman SH, Rasmussen SGF, et al.. Identification of Chromatophore Membrane Protein Complexes Formed under Different Nitrogen Availability Conditions in Rhodospirillum rubrum. Journal of Proteome Research. 2011;10:2703-2714.
Sawada T, Gellman SH. Structural Mimicry of the alpha-Helix in Aqueous Solution with an Isoatomic alpha/beta/gamma-Peptide Backbone. Journal of the American Chemical Society. 2011;133:7336-7339.
Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, et al.. Structure and function of an irreversible agonist-beta(2) adrenoceptor complex. Nature. 2011;469:236-U129.
Rasmussen SGF, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, et al.. Crystal structure of the beta(2) adrenergic receptor-Gs protein complex. Nature. 2011;477:549-U311.
Rasmussen SGF, Choi H-J, Fung JJ, Pardon E, Casarosa P, Chae PS, et al.. Structure of a nanobody-stabilized active state of the beta(2) adrenoceptor. Nature. 2011;469:175-U59.
Pomerantz WC, Yuwono VM, Drake R, Hartgerink JD, Abbott NL, Gellman SH. Lyotropic Liquid Crystals Formed from ACHC-Rich beta-Peptides. Journal of the American Chemical Society. 2011;133:13604-13613.
Lee EF, Smith BJ, Horne SW, Mayer KN, Evangelista M, Colman PM, et al.. Structural Basis of Bcl-x(L) Recognition by a BH3-Mimetic alpha/beta-Peptide Generated by Sequence-Based Design. Chembiochem. 2011;12:2025-2032.
Johnson LM, Horne SW, Gellman SH. Broad Distribution of Energetically Important Contacts across an Extended Protein Interface. Journal of the American Chemical Society. 2011;133:10038-10041.
Guo L, Zhang W, Reidenbach AG, Giuliano MW, Guzei IA, Spencer LC, et al.. Characteristic Structural Parameters for the gamma-Peptide 14-Helix: Importance of Subunit Preorganization. Angewandte Chemie-International Edition. 2011;50:5843-5846.
Buchanan EG, James, William H. III, Gutberlet A, Dean JC, Guo L, Gellman SH, et al.. Single-conformation spectroscopy and population analysis of model gamma-peptides: New tests of amide stacking. Faraday Discussions. 2011;150:209-226.
Acevedo-Velez C, Andre G, Dufrene YF, Gellman SH, Abbott NL. Single-Molecule Force Spectroscopy of beta-Peptides That Display Well-Defined Three-Dimensional Chemical Patterns. Journal of the American Chemical Society. 2011;133:3981-3988.
Segman-Magidovich S, Lee M-R, Vaiser V, Struth B, Gellman SH, Rapaport H. Sheet-Like Assemblies of Charged Amphiphilic α/β-Peptides at the Air-Water Interface. Chemistry-A European Journal. 2011;17:14857-14866, S14857/1-S14857/6.
James WH, Buchanan EG, Muller CW, Dean JC, Kosenkov D, Slipchenko LV, et al.. Evolution of Amide Stacking in Larger γ-Peptides: Triamide H-Bonded Cycles. Journal of Physical Chemistry A. 2011;115:13783-13798.
James WH, Buchanan EG, Guo L, Gellman SH, Zwier TS. Competition between Amide Stacking and Intramolecular H Bonds in γ-Peptide Derivatives: Controlling Nearest-Neighbor Preferences. Journal of Physical Chemistry A. 2011;115:11960-11970.
Freire F, Almeida AM, Fisk JD, Steinkruger JD, Gellman SH. Impact of Strand Length on the Stability of Parallel-β-Sheet Secondary Structure. Angewandte Chemie-International Edition. 2011;50:8735-8738, S8735/1-S8735/28.
Zhang J, Gellman SH, Stahl SS. Kinetics of Anionic Ring-Opening Polymerization of Variously Substituted beta-Lactams: Homopolymerization and Copolymerization. Macromolecules. 2010;43:5618-5626.
Thiele CM, Pomerantz WC, Abbott NL, Gellman SH. Lyotropic liquid crystalline phases from helical beta-peptides as alignment media. Chemical Communications. 2010;47:502-504.
Segman S, Lee M-R, Vaiser V, Gellman SH, Rapaport H. Highly Stable Pleated-Sheet Secondary Structure in Assemblies of Amphiphilic alpha/beta-Peptides at the Air-Water Interface. Angewandte Chemie-International Edition. 2010;49:716-719.
Price JL, Horne SW, Gellman SH. Structural Consequences of beta-Amino Acid Preorganization in a Self-Assembling alpha/beta-Peptide: Fundamental Studies of Foldameric Helix Bundles. Journal of the American Chemical Society. 2010;132:12378-12387.
Karlsson AJ, Flessner RM, Gellman SH, Lynn DM, Palecek SP. Polyelectrolyte Multilayers Fabricated from Antifungal beta-Peptides: Design of Surfaces that Exhibit Antifungal Activity Against Candida albicans. Biomacromolecules. 2010;11:2321-2328.
James WH, Baquero EE, Choi SH, Gellman SH, Zwier TS. Laser Spectroscopy of Conformationally Constrained alpha/beta-Peptides: Ac-ACPC-Phe-NHMe and Ac-Phe-ACPC-NHMe. Journal of Physical Chemistry A. 2010;114:1581-1591.
Dohm MT, Mowery BP, Czyzewski AM, Stahl SS, Gellman SH, Barron AE. Biophysical Mimicry of Lung Surfactant Protein B by Random Nylon-3 Copolymers. Journal of the American Chemical Society. 2010;132:7957-7967.
Choi SH, Guzei IA, Spencer LC, Gellman SH. Crystallographic Characterization of 12-Helical Secondary Structure in beta-Peptides Containing Side Chain Groups. Journal of the American Chemical Society. 2010;132:13879-13885.
Chae PS, Rasmussen SGF, Rana RR, Gotfryd K, Chandra R, Goren MA, et al.. Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins. Nature Methods. 2010;7:1003-U90.
Chae PS, Laible PD, Gellman SH. Tripod amphiphiles for membrane protein manipulation. Molecular Biosystems. 2010;6:89-94.
Chae PS, Guzei IA, Gellman SH. Crystallographic Characterization of N-Oxide Tripod Amphiphiles. Journal of the American Chemical Society. 2010;132:1953-1959.
Chae PS, Gotfryd K, Pacyna J, Miercke LJW, Rasmussen SGF, Robbins RA, et al.. Tandem Facial Amphiphiles for Membrane Protein Stabilization. Journal of the American Chemical Society. 2010;132:16750-16752.
Steinkruger JD, Woolfson DN, Gellman SH. Side-Chain Pairing Preferences in the Parallel Coiled-Coil Dimer Motif: Insight on Ion Pairing between Core and Flanking Sites. Journal of the American Chemical Society. 2010;132:7586-7588.
Price JL, Hadley EB, Steinkruger JD, Gellman SH. Detection and Analysis of Chimeric Tertiary Structures by Backbone Thioester Exchange: Packing of an α Helix against an α/β-Peptide Helix. Angewandte Chemie-International Edition. 2010;49:368-371, S368/1-S368/79.
Guo L, Almeida AM, Zhang W, Reidenbach AG, Choi SH, Guzei IA, et al.. Helix formation in preorganized β/γ-peptide foldamers: Hydrogen-bond analogy to the α-helix without α-amino acid residues. Journal of the American Chemical Society. 2010;132:7868-7869.
Zhang JH, Kissounko DA, Lee SE, Gellman SH, Stahl SS. Access to Poly-beta-Peptides with Functionalized Side Chains and End Groups via Controlled Ring-Opening Polymerization of beta-Lactams. Journal of the American Chemical Society. 2009;131:1589-1597.
Stephenson NA, Zhu J, Gellman SH, Stahl SS. Catalytic Transamidation Reactions Compatible with Tertiary Amide Metathesis under Ambient Conditions. Journal of the American Chemical Society. 2009;131:10003-10008.
Muller MM, Windsor MA, Pomerantz WC, Gellman SH, Hilvert D. A Rationally Designed Aldolase Foldamer. Angewandte Chemie-International Edition. 2009;48:922-925.
Mowery BP, Lindner AH, Weisblum B, Stahl SS, Gellman SH. Structure-activity Relationships among Random Nylon-3 Copolymers That Mimic Antibacterial Host-Defense Peptides. Journal of the American Chemical Society. 2009;131:9735-9745.
Miller CA, Gellman SH, Abbott NL, de Pablo JJ. Association of Helical beta-Peptides and their Aggregation Behavior from the Potential of Mean Force in Explicit Solvent. Biophysical Journal. 2009;96:4349-4362.
Lee M-R, Stahl SS, Gellman SH, Masters KS. Nylon-3 Copolymers that Generate Cell-Adhesive Surfaces Identified by Library Screening. Journal of the American Chemical Society. 2009;131:16779-16789.
Lee EF, Sadowsky JD, Smith BJ, Czabotar PE, Peterson-Kaufman KJ, Colman PM, et al.. High-Resolution Structural Characterization of a Helical alpha/beta-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-x(L). Angewandte Chemie-International Edition. 2009;48:4318-4322.
Karlsson AJ, Pomerantz WC, Neilsen KJ, Gellman SH, Palecek SP. Effect of Sequence and Structural Properties on 14-Helical beta-Peptide Activity against Candida albicans Planktonic Cells and Biofilms. ACS Chemical Biology. 2009;4:567-579.
James WH, Baquero EE, Shubert VA, Choi SH, Gellman SH, Zwier TS. Single-Conformation and Diastereomer Specific Ultraviolet and Infrared Spectroscopy of Model Synthetic Foldamers: alpha/beta-Peptides. Journal of the American Chemical Society. 2009;131:6574-6590.
Horne WS, Johnson LM, Ketas TJ, Klasse PJ, Lu M, Moore JP, et al.. Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers. Proceedings of the National Academy of Sciences of the United States of America. 2009;106:14751-14756.
Choi SH, Guzei IA, Spencer LC, Gellman SH. Crystallographic Characterization of Helical Secondary Structures in 2:1 and 1:2 alpha/beta-Peptides. Journal of the American Chemical Society. 2009;131:2917-2924.
Pomerantz WC, Hadley EB, Fry CG, Gellman SH. In situ monitoring of backbone thioester exchange by 19F NMR. Chembiochem. 2009;10:2177-2181.
Lu D, Windsor MA, Gellman SH, Keck JL. Peptide Inhibitors Identify Roles for SSB C-Terminal Residues in SSB/Exonuclease I Complex Formation. Biochemistry. 2009;48:6764-6771.
James, William H. III, Muller CW, Buchanan EG, Nix MGD, Guo L, Roskop L, et al.. Intramolecular Amide Stacking and Its Competition with Hydrogen Bonding in a Small Foldamer. Journal of the American Chemical Society. 2009;131:14243-14245.
Guo L, Chi Y, Almeida AM, Guzei IA, Parker BK, Gellman SH. Stereospecific synthesis of conformationally constrained γ-amino acids: New foldamer building blocks that support helical secondary structure. Journal of the American Chemical Society. 2009;131:16018-16020.
Giuliano MW, Horne SW, Gellman SH. An α/β-peptide helix bundle with a pure β3-amino acid core and a distinctive quaternary structure. Journal of the American Chemical Society. 2009;131:9860-9861.
Freire F, Gellman SH. Macrocyclic design strategies for small, stable parallel β-sheet scaffolds. Journal of the American Chemical Society. 2009;131:7970-7972.
Pomerantz WC, Yuwono VM, Pizzey CL, Hartgerink JD, Abbott NL, Gellman SH. Nanofibers and lyotropic liquid crystals from a class of self-assembling beta-peptides. Angewandte Chemie-International Edition. 2008;47:1241-1244.
Peterson KJ, Sadowsky JD, Scheef EA, Pal S, Kourentzi KD, Willson RC, et al.. A fluorescence polarization assay for identifying ligands that bind to vascular endothelial growth factor. Analytical Biochemistry. 2008;378:8-14.
Murray JK, Sadowsky JD, Scalf M, Smith LM, Tomita Y, Gellman SH. Exploration of structure - Activity relationships among foldamer ligands for a specific protein binding site via parallel and split-and-mix library synthesis. Journal of Combinatorial Chemistry. 2008;10:204-215.
Miller CA, Gellman SH, Abbott NL, De Pablo JJ. Mechanical stability of helical beta-peptides and a comparison of explicit and implicit solvent models. Biophysical Journal. 2008;95:3123-3136.
Lee MR, Stahl SS, Gellman SH. Synthesis of beta-Lactams Bearing Functionalized Side Chains from a Readily Available Precursor. Organic Letters. 2008;10:5317-5319.
Horne SW, Price JL, Gellman SH. Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly. Proceedings of the National Academy of Sciences of the United States of America. 2008;105:9151-9156.
Horne WS, Gellman SH. Foldamers with Heterogeneous Backbones. Accounts of Chemical Research. 2008;41:1399-1408.
Horne SW, Boersma MD, Windsor MA, Gellman SH. Sequence-based design of alpha/beta-peptide foldamers that mimic BH3 domains. Angewandte Chemie-International Edition. 2008;47:2853-2856.
Hoerter JM, Otte KM, Gellman SH, Cui Q, Stahl SS. Discovery and mechanistic study of Al-III-catalyzed transamidation of tertiary amides. Journal of the American Chemical Society. 2008;130:647-654.
Hadley EB, Testa OD, Woolfson DN, Gellman SH. Preferred side-chain constellations at antiparallel coiled-coil interfaces. Proceedings of the National Academy of Sciences of the United States of America. 2008;105:530-535.
Epand RF, Mowery BP, Lee SE, Stahl SS, Lehrer RI, Gellman SH, et al.. Dual mechanism of bacterial lethality for a cationic sequence-random copolymer that mimics host-defense antimicrobial peptides. Journal of Molecular Biology. 2008;379:38-50.
Choi SH, Guzei IA, Spencer LC, Gellman SH. Crystallographic characterization of helical secondary structures in alpha/beta-peptides with 1 : 1 residue alternation. Journal of the American Chemical Society. 2008;130:6544-6550.
Boersma MD, Sadowsky JD, Tomita YA, Gellman SH. Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein-protein recognition: Application to the Bim BH3 domain. Protein Science. 2008;17:1232-1240.
Baquero EE, James, William H. III, Choi SH, Gellman SH, Zwier TS. Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta(3)-hPhe-beta(3)-hAla-NHMe and Ac-beta(3)-hAla-beta(3)-hPhe-NHMe. Journal of the American Chemical Society. 2008;130:4795-4807.
Baquero EE, James, William H. III, Choi SH, Gellman SH, Zwier TS. Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta(3)-hPhe-NHMe and Ac-beta(3)-hTyr-NHMe. Journal of the American Chemical Society. 2008;130:4784-4794.
Akkarawongsa R, Potocky TB, English EP, Gellman SH, Brandt CR. Inhibition of herpes simplex virus type 1 infection by cationic beta-peptides. Antimicrobial Agents and Chemotherapy. 2008;52:2120-2129.
Zhu X, Koenig P, Gellman SH, Yethiraj A, Cui Q. Establishing Effective Simulation Protocols for β- and α/β-Peptides. II. Molecular Mechanical (MM) Model for a Cyclic β-Residue. Journal of Physical Chemistry B. 2008;112:5439-5448.
Vaz E, Pomerantz WC, Geyer M, Gellman SH, Brunsveld L. Comparison of design strategies for promotion of β-peptide 14-helix stability in water. Chembiochem. 2008;9:2254-2259.
Pomerantz WC, Grygiel TLR, Lai JR, Gellman SH. Distinctive circular dichroism signature for 14-helix-bundle formation by β-peptides. Organic Letters. 2008;10:1799-1802.
Pizzey CL, Pomerantz WC, Sung B-J, Yuwono VM, Gellman SH, Hartgerink JD, et al.. Characterization of nanofibers formed by self-assembly of β-peptide oligomers using small angle x-ray scattering. Journal of Chemical Physics. 2008;129:095103/1-095103/8.
Miller CA, Hernandez-Ortiz JP, Abbott NL, Gellman SH, De Pablo JJ. Dipole-induced self-assembly of helical β-peptides. Journal of Chemical Physics. 2008;129:015102/1-015102/10.
Freire F, Fisk JD, Peoples AJ, Ivancic M, Guzei IA, Gellman SH. Diacid Linkers That Promote Parallel β-Sheet Secondary Structure in Water. Journal of the American Chemical Society. 2008;130:7839-7841.
Chi Y, Guo L, Kopf NA, Gellman SH. Enantioselective organocatalytic Michael addition of aldehydes to nitroethylene: efficient access to γ2-amino acids. Journal of the American Chemical Society. 2008;130:5608-5609.
Chae PS, Wander MJ, Bowling AP, Laible PD, Gellman SH. Glycotripod amphiphiles for solubilization and stabilization of a membrane-protein superassembly: importance of branching in the hydrophilic portion. Chembiochem. 2008;9:1706-1709.
Schmitt MA, Weisblum B, Gellman SH. Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides. Journal of the American Chemical Society. 2007;129:417-428.
Sadowsky JD, Murray JK, Tomita Y, Gellman SH. Exploration of backbone space in foldamers containing alpha- and beta-amino acid residues: Developing protease-resistant oligomers that bind tightly to the BH3-recognition cleft of Bcl-x(L). Chembiochem. 2007;8:903-916.
Sadowsky JD, Douglas Fairlie W, Hadley EB, Lee H-S, Umezawa N, Nikolovska-Coleska Z, et al.. (alpha/beta+alpha)-Peptide antagonists of BH3 Domain/Bcl-x(L) recognition: Toward general strategies for foldamer-based inhibition of protein-protein interactions. Journal of the American Chemical Society. 2007;129:139-154.
Price JL, Home WS, Gellman SH. Heterogeneous helix-bundle quaternary structure formed by alpha/beta-peptide foldamers and alpha-peptides. Biopolymers. 2007;88:568-568.
Pomerantz WC, Pizzey C, Yuwono V, Paramanov S, Hartgerink J, Gellman SH, et al.. Lyotropic liquid crystals from designed helical beta peptides. Biopolymers. 2007;88:570-570.
Pomerantz WC, Cadwell KD, Hsu Y-J, Gellman SH, Abbott NL. Sequence dependent behavior of amphiphilic beta-peptides on gold surfaces. Chemistry of Materials. 2007;19:4436-4441.
Murray JK, Gellman SH. Parallel synthesis of peptide libraries using microwave irradiation. Nature Protocols. 2007;2:624-631.
Murray JK, Gellman SH. Targeting protein-protein interactions: Lessons from p53/MDM2. Biopolymers. 2007;88:657-686.
Kissounko DA, Hoerter JM, Guzei IA, Cui Q, Gellman SH, Stahl SS. Ti-IV-mediated reactions between primary amines and secondary carboxamides: Amidine formation versus transamidation. Journal of the American Chemical Society. 2007;129:1776-1783.
Choi SH, Guzei IA, Gellman SH. Helical secondary structures in alpha/beta-peptides by crystallographic characterization. Biopolymers. 2007;88:607-607.
Chi Y, English EP, Pomerantz WC, Horne SW, Joyce LA, Alexander LR, et al.. Practical synthesis of enantiomerically pure beta(2)-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes. Journal of the American Chemical Society. 2007;129:6050-6055.
Bell CM, Kissounko DA, Gellman SH, Stahl SS. Catalytic metathesis of simple secondary amides. Angewandte Chemie-International Edition. 2007;46:761-763.
Tang L, Hopper ED, Tong Y, Sadowsky JD, Peterson KJ, Gellman SH, et al.. H/D Exchange- and Mass Spectrometry-Based Strategy for the Thermodynamic Analysis of Protein-Ligand Binding. Analytical Chemistry. 2007;79:5869-5877.
Price JL, Horne SW, Gellman SH. Discrete heterogeneous quaternary structure formed by α/β-peptide foldamers and α-peptides. Journal of the American Chemical Society. 2007;129:6376-6377.
Potocky TB, Silvius J, Menon AK, Gellman SH. HeLa cell entry by guanidinium-rich β-peptides: importance of specific cation-cell surface interactions. Chembiochem. 2007;8:917-926.
Mowery BP, Lee SE, Kissounko DA, Epand RF, Epand RM, Weisblum B, et al.. Mimicry of antimicrobial host-defense peptides by random copolymers. Journal of the American Chemical Society. 2007;129:15474-15476.
Lee M-R, Raguse TL, Schinnerl M, Pomerantz WC, Wang X, Wipf P, et al.. Origins of the high 14-helix propensity of cyclohexyl-rigidified residues in β-peptides. Organic Letters. 2007;9:1801-1804.
Horne SW, Price JL, Keck JL, Gellman SH. Helix Bundle Quaternary Structure from α/β-Peptide Foldamers. Journal of the American Chemical Society. 2007;129:4178-4180.
Hadley EB, Witek AM, Freire F, Peoples AJ, Gellman SH. Thermodynamic analysis of β-sheet secondary structure by backbone thioester exchange. Angewandte Chemie-International Edition. 2007;46:7056-7059.
Cornilescu G, Hadley EB, Woll MG, Markley JL, Gellman SH, Cornilescu CC. Solution structure of a small protein containing a fluorinated side chain in the core. Protein Science. 2007;16:14-19.
Choi SH, Guzei IA, Gellman SH. Crystallographic characterization of the α/β-peptide 14/15-helix. Journal of the American Chemical Society. 2007;129:13780-13781.
Woll MG, Hadley EB, Mecozzi S, Gellman SH. Stabilizing and destabilizing effects of phenylalanine -> F-5-phenylalanine mutations on the folding of a small protein. Journal of the American Chemical Society. 2006;128:15932-15933.
Schmitt MA, Choi SH, Guzei IA, Gellman SH. New helical foldamers: Heterogeneous backbones with 1 : 2 and 2 : 1 alpha :beta-amino acid residue patterns. Journal of the American Chemical Society. 2006;128:4538-4539.
Rathore N, Gellman SH, de Pablo JJ. Thermodynamic stability of beta-peptide helices and the role of cyclic residues. Biophysical Journal. 2006;91:3425-3435.
Pal S, Wu J, Murray JK, Gellman SH, Wozniak MA, Keely PJ, et al.. An antiangiogenic neurokinin-B/thromboxane A2 regulatory axis. Journal of Cell Biology. 2006;174:1047-1058.
Lai JR, Epand RF, Weisblum B, Epand RM, Gellman SH. Roles of salt and conformation in the biological and physicochemical behavior of protegrin-1 and designed analogues: Correlation of antimicrobial, hemolytic, and lipid bilayer-perturbing activities. Biochemistry. 2006;45:15718-15730.
Hoerter JM, Otte KM, Gellman SH, Stahl SS. Mechanism of Al-III-catalyzed transamidation of unactivated secondary carboxamides. Journal of the American Chemical Society. 2006;128:5177-5183.
Hadley EB, Gellman SH. An antiparallel alpha-helical coiled-coil model system for rapid assessment of side-chain recognition at the hydrophobic interface. Journal of the American Chemical Society. 2006;128:16444-16445.
English EP, Chumanov RS, Gellman SH, Compton T. Rational development of beta-peptide inhibitors of human cytomegalovirus entry. Journal of Biological Chemistry. 2006;281:2661-2667.
Pomerantz WC, Abbott NL, Gellman SH. Lyotropic Liquid Crystals from Designed Helical β-Peptides. Journal of the American Chemical Society. 2006;128:8730-8731.
Murray JK, Gellman SH. Microwave-assisted parallel synthesis of a 14-helical beta-peptide library. Journal of Combinatorial Chemistry. 2006;8:58-65.
Karlsson AJ, Pomerantz WC, Weisblum B, Gellman SH, Palecek SP. Antifungal activity from 14-helical β-peptides. Journal of the American Chemical Society. 2006;128:12630-12631.
Gellman SH. Structure and function in foldamers. Pept. Sci. 2006;43rd:72.
Fisk JD, Schmitt MA, Gellman SH. Thermodynamic Analysis of Autonomous Parallel β-Sheet Formation in Water. Journal of the American Chemical Society. 2006;128:7148-7149.
Epand RF, Schmitt MA, Gellman SH, Epand RM. Role of membrane lipids in the mechanism of bacterial species selective toxicity by two α/β-antimicrobial peptides. Biochim. Biophys. Acta, Biomembr. 2006;1758:1343-1350.
Chi Y, Gellman SH. Enantioselective Organocatalytic Aminomethylation of Aldehydes: A Role for Ionic Interactions and Efficient Access to β2-Amino Acids. Journal of the American Chemical Society. 2006;128:6804-6805.
Schmitt MA, Choi SH, Guzei IA, Gellman SH. Residue requirements for helical folding in short alpha/beta-peptides: Crystallographic characterization of the 11-helix in an optimized sequence. Journal of the American Chemical Society. 2005;127:13130-13131.
Sadowsky JD, Schmitt MA, Lee HS, Umezawa N, Wang SM, Tomita Y, et al.. Chimeric (alpha/beta plus alpha)-peptide ligands for the BH3-recognition cleft of Bcl-x(L): Critical role of the molecular scaffold in protein surface recognition. Journal of the American Chemical Society. 2005;127:11966-11968.
Potocky TB, Menon AK, Gellman SH. Effects of conformational stability and geometry of guanidinium display on cell entry by beta-peptides. Journal of the American Chemical Society. 2005;127:3686-3687.
Porter EA, Weisblum B, Gellman SH. Use of parallel synthesis to probe structure-activity relationships among 12-helical beta-peptides: Evidence of a limit on antimicrobial activity. Journal of the American Chemical Society. 2005;127:11516-11529.
Murray JK, Farooqi B, Sadowsky JD, Scalf M, Freund WA, Smith LM, et al.. Efficient synthesis of a beta-peptide combinatorial library with microwave irradiation. Journal of the American Chemical Society. 2005;127:13271-13280.
Huck BR, Gellman SH. Synthesis of 2,2-disubstituted pyrrolidine-4-carboxylic acid derivatives and their incorporation into beta-peptide oligomers. Journal of Organic Chemistry. 2005;70:3353-3362.
Gelman MA, Gellman SH. Using constrained b-amino acid residues to control b-peptide shape and function. Enantioselective Synthesis of b-Amino Acids (2nd Edition). 2005;:527-591.
Epand RF, Schmitt MA, Gellman SH, Sen A, Auger M, Hughes DW, et al.. Bacterial species selective toxicity of two isomeric alpha/beta-peptides: Role of membrane lipids. Molecular Membrane Biology. 2005;22:457-469.
Gilbert PUPA, Schmitt MA, Gellman SH. Spectromicroscopy at the organic-inorganic interface in biominerals. American Journal of Science. 2005;305:673-686.
Theisen MJ, Potocky TB, D. McQuade T, Gellman SH, Chiu ML. Crystallization of bacteriorhodopsin solubilized by a tripod amphiphile. Biochimica et Biophysica Acta, Proteins and Proteomics. 2005;1751:213-216.
Murray JK, Gellman SH. Application of microwave irradiation to the synthesis of 14-helical beta-peptides. Organic Letters. 2005;7:1517-1520.
Kissounko DA, Guzei IA, Gellman SH, Stahl SS. Titanium(IV)-mediated conversion of carboxamides to amidines and implications for catalytic transamidation. Organometallics. 2005;24:5208-5210.
Gellman SH. Structure and function in foldamers. Polymer Preprints. 2005;46:169.
Espinosa JF, Syud FA, Gellman SH. An autonomously folding beta-hairpin derived from the human YAP65 WW domain: Attempts to define a minimum ligand-binding motif. Biopolymers. 2005;80:303-311.
Eldred SE, Pancost MR, Otte KM, Rozema D, Stahl SS, Gellman SH. Effects of side chain configuration and backbone spacing on the gene delivery properties of lysine-derived cationic polymers. Bioconjugate Chemistry. 2005;16:694-699.
Chi YG, Gellman SH. Diphenylprolinol methyl ether: A highly enantioselective catalyst for Michael addition of aldehydes to simple enones. Organic Letters. 2005;7:4253-4256.
Chi Y, Peelen TJ, Gellman SH. A rapid 1H NMR assay for enantiomeric excess of α-substituted aldehydes. Organic Letters. 2005;7:3469-3472.
Woll MG, Gellman SH. Backbone thioester exchange: A new approach to evaluating higher order structural stability in polypeptides. Journal of the American Chemical Society. 2004;126:11172-11174.
Schmitt MA, Weisblum B, Gellman SH. Unexpected relationships between structure and function in alpha,beta-peptides: Antimicrobial foldamers with heterogeneous backbones. Journal of the American Chemical Society. 2004;126:6848-6849.
Lai JR, Fisk JD, Weisblum B, Gellman SH. Hydrophobic core repacking in a coiled-coil dimer via phage display: Insights into plasticity and specificity at a protein-protein interface. Journal of the American Chemical Society. 2004;126:10514-10515.
Peelen TJ, Chi YG, English EP, Gellman SH. Synthesis of 4,4-disubstituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into 12-helical beta-peptides. Organic Letters. 2004;6:4411-4414.
Langenhan JM, Gellman SH. Effects of alternative side chain pairings and reverse turn sequences on antiparallel sheet structure in beta-peptide hairpins. Organic Letters. 2004;6:937-940.
Hayen A, Schmitt MA, Ngassa FN, Thomasson KA, Gellman SH. Two helical conformations from a single foldamer backbone: "Split personality" in short alpha/beta-peptides. Angewandte Chemie-International Edition. 2004;43:505-510.
Gelman MA, Weisblum B, Lynn DM, Gellman SH. Biocidal activity of polystyrenes that are cationic by virtue of protonation. Organic Letters. 2004;6:557-560.
Epand RF, Raguse TL, Gellman SH, Epand RM. Antimicrobial 14-helical beta-peptides: Potent bilayer disrupting agents. Biochemistry. 2004;43:9527-9535.
Syud FA, Stanger HE, Mortell HS, Espinosa JF, Fisk JD, Fry CG, et al.. Influence of strand number on antiparallel beta-sheet stability in designed three- and four-stranded beta-sheets. Journal of Molecular Biology. 2003;326:553-568.
Raguse TL, Lai JR, Gellman SH. Environment-independent 14-helix formation in short beta-peptides: Striking a balance between shape control and functional diversity. Journal of the American Chemical Society. 2003;125:5592-5593.
Potocky TB, Menon AK, Gellman SH. Cytoplasmic and nuclear delivery of a TAT-derived peptide and a beta-peptide after endocytic uptake into HeLa cells. Journal of Biological Chemistry. 2003;278:50188-50194.
Park JS, Lee HS, Lai JR, Kim BM, Gellman SH. Accommodation of alpha-substituted residues in the beta-peptide 12-helix: Expanding the range of substitution patterns available to a foldamer scaffold. Journal of the American Chemical Society. 2003;125:8539-8545.
Langenhan JM, Gellman SH. Preparation of protected syn-alpha,beta-dialkyl beta-amino acids that contain polar side chain functionality. Journal of Organic Chemistry. 2003;68:6440-6443.
Epand RF, Umezawa N, Porter EA, Gellman SH, Epand RM. Interactions of the antimicrobial beta-peptide beta-17 with phospholipid vesicles differ from membrane interactions of magainins. European Journal of Biochemistry. 2003;270:1240-1248.
Eldred SE, Stone DA, Gellman SH, Stahl SS. Catalytic transamidation under moderate conditions. Journal of the American Chemical Society. 2003;125:3422-3423.
Schinnerl M, Murray JK, Langenhan JM, Gellman SH. Asymmetric synthesis of a new helix-forming beta-amino acid: trans-4-aminopiperidine-3-carboxylic acid. European Journal of Organic Chemistry. 2003;:721-726.
Lee H-S, Park J-S, Kim BM, Gellman SH. Efficient Synthesis of Enantiomerically Pure β2-Amino Acids via Chiral Isoxazolidinones. Journal of Organic Chemistry. 2003;68:1575-1578.
Langenhan JM, Guzei IA, Gellman SH. Parallel sheet secondary structure in beta-peptides. Angewandte Chemie-International Edition. 2003;42:2402-2405.
Lai JR, Gellman SH. Reinvestigation of the proposed folding and self-association of the Neuropeptide Head Activator. Protein Science. 2003;12:560-566.
Huck BR, Fisk JD, Guzei IA, Carlson HA, Gellman SH. Secondary Structural Preferences of 2,2-Disubstituted Pyrrolidine-4-carboxylic Acid Oligomers: β-Peptide Foldamers that Cannot Form Internal Hydrogen Bonds. Journal of the American Chemical Society. 2003;125:9035-9037.
Gelman MA, Richter S, Cao H, Umezawa N, Gellman SH, Rana TM. Selective binding of TAR RNA by a tat-derived beta-peptide. Organic Letters. 2003;5:3563-3565.
Gellman SH. Structure and function in b-peptide foldamers. Polymer Preprints. 2003;44:461.
Bruckner AM, Garcia M, Marsh A, Gellman SH, Diederichsen U. Synthesis of novel nucleo-beta-amino acids and nucleobase-functionalized beta-peptides. European Journal of Organic Chemistry. 2003;:3555-3561.
Bruckner AM, Chakraborty P, Gellman SH, Diederichsen U. Molecular architecture with functionalized beta-peptide helices. Angewandte Chemie-International Edition. 2003;42:4395-4399.
Woll MG, Fisk JD, LePlae PR, Gellman SH. Stereoselective synthesis of 3-substituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into short 12-helical beta-peptides that fold in water. Journal of the American Chemical Society. 2002;124:12447-12452.
Umezawa N, Gelman MA, Haigis MC, Raines RT, Gellman SH. Translocation of a beta-peptide across cell membranes. Journal of the American Chemical Society. 2002;124:368-369.
Raguse TL, Porter EA, Weisblum B, Gellman SH. Structure-activity studies of 14-helical antimicrobial beta-peptides: Probing the relationship between conformational stability and antimicrobial potency. Journal of the American Chemical Society. 2002;124:12774-12785.
Porter EA, Weisblum B, Gellman SH. Mimicry of host-defense peptides by unnatural oligomers: Antimicrobial beta-peptides. Journal of the American Chemical Society. 2002;124:7324-7330.
LePlae PR, Fisk JD, Porter EA, Weisblum B, Gellman SH. Tolerance of acyclic residues in the beta-peptide 12-helix: Access to diverse side-chain arrays for biological applications. Journal of the American Chemical Society. 2002;124:6820-6821.
Arnold U, Hinderaker MP, Nilsson BL, Huck BR, Gellman SH, Raines RT. Protein prosthesis: A semisynthetic enzyme with a beta-peptide reverse turn. Journal of the American Chemical Society. 2002;124:8522-8523.
Raguse TL, Lai JR, Gellman SH. Evidence that the beta-peptide 14-Helix is Stabilized by beta(3)-residues with side-chain branching adjacent to the beta-carbon atom. Helvetica Chimica Acta. 2002;85:4154-4164.
Porter EA, Wang XF, Schmitt MA, Gellman SH. Synthesis and 12-helical secondary structure of beta-peptides containing (2R,3R)-aminoproline. Organic Letters. 2002;4:3317-3319.
Lai JR, Huck BR, Weisblum B, Gellman SH. Design of non-cysteine-containing antimicrobial beta-hairpins: Structure-activity relationship studies with linear protegrin-1 analogues. Biochemistry. 2002;41:12835-12842.
Knight SMG, Umezawa N, Lee HS, Gellman SH, Kay BK. A fluorescence polarization assay for the identification of inhibitors of the p53-DM2 protein-protein interaction. Analytical Biochemistry. 2002;300:230-236.
Hilario J, Kubelka J, Syud FA, Gellman SH, Keiderling TA. Spectroscopic characterization of selected β-sheet hairpin models. Biopolymers. 2002;61:233-236.
Gellman SH, Woolfson DN. Mini-proteins Trp the light fantastic. Nature Structural Biology. 2002;9:408-410.
Gellman SH, Raines RT. Model systems - This year's model - Editorial overview. Current Opinion in Chemical Biology. 2002;6:727-728.
Gellman SH. Beta-peptide foldamers show biomedical potential. sp2. 2002;1:30-31.
Espinosa JF, Syud FA, Gellman SH. Analysis of the factors that stabilize a designed two-stranded antiparallel beta-sheet. Protein Science. 2002;11:1492-1505.
Raguse TL, Lai JR, LePlae PR, Gellman SH. Toward beta-peptide tertiary structure: Self-association of an amphiphilic 14-helix in aqueous solution. Organic Letters. 2001;3:3963-3966.
Langenhan JM, Fisk JD, Gellman SH. Evaluation of hydrogen bonding complementarity between a secondary sulfonamide and an alpha-amino acid residue. Organic Letters. 2001;3:2559-2562.
Woll MG, Lai JR, Guzei IA, Taylor SJC, Smith MEB, Gellman SH. Parallel sheet secondary structure in gamma-peptides. Journal of the American Chemical Society. 2001;123:11077-11078.
Syud FA, Stanger HE, Gellman SH. Interstrand side chain-side chain interactions in a designed beta-hairpin: Significance of both lateral and diagonal pairings. Journal of the American Chemical Society. 2001;123:8667-8677.
Stanger HE, Syud FA, Espinosa JF, Giriatt I, Muir T, Gellman SH. Length-dependent stability and strand length limits in antiparallel beta-sheet secondary structure. Proceedings of the National Academy of Sciences of the United States of America. 2001;98:12015-12020.
McKay SL, Haptonstall B, Gellman SH. Beyond the hydrophobic effect: Attractions involving heteroaromatic rings in aqueous solution. Journal of the American Chemical Society. 2001;123:1244-1245.
LePlae PR, Umezawa N, Lee HS, Gellman SH. An efficient route to either enantiomer of trans-2-aminocyclopentanecarboxylic acid. Journal of Organic Chemistry. 2001;66:5629-5632.
Lee HS, Syud FA, Wang XF, Gellman SH. Diversity in short beta-peptide 12-helices: High-resolution structural analysis in aqueous solution of a hexamer containing sulfonylated pyrrolidine residues. Journal of the American Chemical Society. 2001;123:7721-7722.
Lee HS, LePlae PR, Porter EA, Gellman SH. An efficient route to either enantiomer of orthogonally protected trans-3-aminopyrrolidine-4-carboxylic acid. Journal of Organic Chemistry. 2001;66:3597-3599.
Fisk JD, Gellman SH. A parallel beta-sheet model system that folds in water. Journal of the American Chemical Society. 2001;123:343-344.
Espinosa JF, Munoz V, Gellman SH. Interplay between hydrophobic cluster and loop propensity in beta-hairpin formation. Journal of Molecular Biology. 2001;306:397-402.
Cheng RP, Gellman SH, DeGrado WF. beta-peptides: From structure to function. Chemical Reviews. 2001;101:3219-3232.
Arnold U, Hinderaker MP, Nilsson BL, Huck BR, Gellman SH, Raines RT. Semisynthesis of proteins containing nonnatural modules. Biochemistry. 2001;40:8627-8628.
Yu SM, McQuade DT, Quinn MA, Hackenberger CPR, Krebs MP, Polans AS, et al.. An improved tripod amphiphile for membrane protein solubilization. Protein Science. 2000;9:2518-2527.
Wang X, Espinosa JF, Gellman SH. 12-Helix formation in aqueous solution with short β-peptides containing pyrrolidine-based residues. Journal of the American Chemical Society. 2000;122:4821-4822.
Porter EA, Wang X, Lee H-S, Weisblum B, Gellman SH. Antibiotics: Non-hemolytic β-amino-acid oligomers. Nature. 2000;404:565.
D. McQuade T, Quinn MA, Yu SM, Polans AS, Krebs MP, Gellman SH. Rigid amphiphiles for membrane protein manipulation. Angewandte Chemie-International Edition. 2000;39:758-761.
Huck BR, Fisk JD, Gellman SH. Promotion of sheet formation in α-peptide strands by a β-peptide reverse turn. Organic Letters. 2000;2:2607-2610.
Gardner RR, McKay SL, Gellman SH. Solvent-Dependent Stabilization of the E Configuration of Propargylic Secondary Amides. Organic Letters. 2000;2:2335-2338.
Fisk JD, Powell DR, Gellman SH. Control of hairpin formation via proline configuration in parallel β-sheet model systems. Journal of the American Chemical Society. 2000;122:5443-5447.
Espinosa JF, Gellman SH. A designed β-hairpin containing a natural hydrophobic cluster. Angewandte Chemie-International Edition. 2000;39:2330-2333.
Chung YJ, Huck BR, Christianson LA, Stanger HE, Krauthäuser S, Powell DR, et al.. Stereochemical Control of Hairpin Formation in β-Peptides Containing Dinipecotic Acid Reverse Turn Segments. Journal of the American Chemical Society. 2000;122:3995-4004.
Christianson LA, Lucero MJ, Appella DH, Klein DA, Gellman SH. Improved treatment of cyclic β-amino acids and successful prediction of β-peptide secondary structure using a modified force field: AMBER*C. Journal of Computational Chemistry. 2000;21:763-773.
Barchi, Jr. JJ, Huang X, Appella DH, Christianson LA, Durell SR, Gellman SH. Solution conformations of helix-forming β-amino acid homooligomers. Journal of the American Chemical Society. 2000;122:2711-2718.
Appella DH, LePlae PR, Raguse TL, Gellman SH. (R,R,R)-2,5-Diaminocylohexanecarboxylic Acid, a Building Block for Water-Soluble, Helix-Forming β-Peptides. Journal of Organic Chemistry. 2000;65:4766-4769.
Yang JH, Christianson LA, Gellman SH. Comparison of an HXH three-center hydrogen bond with alternative two-center hydrogen bonds in a model system. Organic Letters. 1999;1:11-13.
Syud FA, Espinosa JF, Gellman SH. NMR-based quantification of beta-sheet populations in aqueous solution through use of reference peptides for the folded and unfolded states. Journal of the American Chemical Society. 1999;121:11577-11578.
Huck BR, Langenhan JM, Gellman SH. Non-hydrogen-bonded secondary structure in beta-peptides: Evidence from circular dichroism of (S)-pyrrolidine-3-carboxylic acid oligomers and (S)-nipecotic acid oligomers. Organic Letters. 1999;1:1717-1720.
Gardner RR, Liang GB, Gellman SH. beta-turn and beta-hairpin mimicry with tetrasubstituted alkenes. Journal of the American Chemical Society. 1999;121:1806-1816.
Daugherty DL, Gellman SH. A fluorescence assay for leucine zipper dimerization: Avoiding unintended consequences of fluorophore attachment. Journal of the American Chemical Society. 1999;121:4325-4333.
Appella DH, Christianson LA, Klein DA, Richards MR, Powell DR, Gellman SH. Synthesis and structural characterization of helix-forming beta-peptides: trans-2-aminocyclopentanecarboxylic acid oligomers. Journal of the American Chemical Society. 1999;121:7574-7581.
Appella DH, Christianson LA, Karle IL, Powell DR, Gellman SH. Synthesis and characterization of trans-2-aminocyclohexanecarboxylic acid oligomers: An unnatural helical secondary structure and implications for beta-peptide tertiary structure. Journal of the American Chemical Society. 1999;121:6206-6212.
Appella DH, Barchi JJ, Durell SR, Gellman SH. Formation of short, stable helices in aqueous solution by beta-amino acid hexamers. Journal of the American Chemical Society. 1999;121:2309-2310.
Yang JH, Gellman SH. Energetic superiority of two-center hydrogen bonding relative to three-center hydrogen bonding in a model system. Journal of the American Chemical Society. 1998;120:9090-9091.
Stanger HE, Gellman SH. Rules for antiparallel beta-sheet design: D-Pro-Gly is superior to L-Asn-Gly for beta-hairpin nucleation. Journal of the American Chemical Society. 1998;120:4236-4237.
Schenck HL, Gellman SH. Use of a designed triple-stranded antiparallel beta-sheet to probe beta-sheet cooperativity in aqueous solution. Journal of the American Chemical Society. 1998;120:4869-4870.
Hanson PE, Gellman SH. Mechanistic comparison of artificial-chaperone-assisted and unassisted refolding of urea-denatured carbonic anhydrase B. Folding and Design. 1998;3:457-468.
Gellman SH. Minimal model systems for beta sheet secondary structure in proteins. Current Opinion in Chemical Biology. 1998;2:717-725.
Gellman SH. Foldamers: A manifesto. Accounts of Chemical Research. 1998;31:173-180.
Daugherty DL, Rozema D, Hanson PE, Gellman SH. Artificial chaperone-assisted refolding of citrate synthase. Journal of Biological Chemistry. 1998;273:33961-33971.
Chung YJ, Christianson LA, Stanger HE, Powell DR, Gellman SH. A beta-peptide reverse turn that promotes hairpin formation. Journal of the American Chemical Society. 1998;120:10555-10556.
Applequist J, Bode KA, Appella DH, Christianson LA, Gellman SH. Theoretical and experimental circular dichroic spectra of the novel helical foldamer poly (1R,2R)-trans-2-aminocyclopentanecarboxylic acid. Journal of the American Chemical Society. 1998;120:4891-4892.
Yang J, Christianson LA, Gellman SH. Energetic superiority of two-center over three-center (bifurcated) hydrogen bonds in solution. FASEB Journal. 1997;11:A1324-A1324.
McQuade DT, McKay SL, Powell DR, Gellman SH. Indifference to hydrogen bonding in a family of secondary amides. Journal of the American Chemical Society. 1997;119:8528-8532.
Krauthauser S, Christianson LA, Powell DR, Gellman SH. Antiparallel sheet formation in beta-peptide foldamers: Effects of beta-amino acid substitution on conformational preference. Journal of the American Chemical Society. 1997;119:11719-11720.
Holmgren SK, Savage PB, Desper JM, Schladetzky KD, Powell DR, Gellman SH. Steric control of oxidation selectivity in macrocyclic phosphine oxide-dithioethers. Tetrahedron. 1997;53:12249-12262.
Haque TS, Gellman SH. Insights on beta-hairpin stability in aqueous solution from peptides with enforced type I' and type II' beta-turns. Journal of the American Chemical Society. 1997;119:2303-2304.
Gellman SH, Cowburn D, McDonnell JM. Hairpin turns. Chemical & Engineering News. 1997;75:6-6.
Gellman SH. Introduction: Molecular Recognition. Chemical Reviews (Washington, D. C.). 1997;97:1231-1232.
Gardner RR, Gellman SH. Secondary effects in flexible hydrogen bonding networks. Tetrahedron. 1997;53:9881-9890.
Gardner RR, Christianson LA, Gellman SH. Quantitative analysis of hydrophobically induced folding in a minimal model system. Journal of the American Chemical Society. 1997;119:5041-5042.
Appella DH, Christianson LA, Klein DA, Powell DR, Huang XL, Barchi JJ, et al.. Residue-based control of helix shape in beta-peptide oligomers. Nature. 1997;387:381-384.
Schenck HL, Dado GP, Gellman SH. Redox-triggered secondary structure changes in the aggregated states of a designed methionine-rich peptide. Journal of the American Chemical Society. 1996;118:12487-12494.
Rozema D, Gellman SH. Artificial chaperone-assisted refolding of denatured-reduced lysozyme: Modulation of the competition between renaturation and aggregation. Biochemistry. 1996;35:15760-15771.
Rozema D, Gellman SH. Artificial chaperone-assisted refolding of carbonic anhydrase B. Journal of Biological Chemistry. 1996;271:3478-3487.
Haque TS, Little JC, Gellman SH. Stereochemical requirements for beta-hairpin formation: Model studies with four-residue peptides and depsipeptides. Journal of the American Chemical Society. 1996;118:6975-6985.
Gellman SH, Haque TS, Newcomb LF. New evidence that the hydrophobic effect and dispersion are not major driving forces for nucleotide base stacking. Biophysical Journal. 1996;71:3523-3525.
Appella DH, Christianson LA, Karle IL, Powell DR, Gellman SH. beta-peptide foldamers: Robust Helix formation in a new family of beta-amino acid oligomers. Journal of the American Chemical Society. 1996;118:13071-13072.
Powell DR, Hanson PE, Gellman SH. (Z)-2-(Benzoyl-aci-nitro)-2-phenylacetonitrile. Acta Crystallographica - Section C - Crystal Structure Communications. 1996;C52:2945-2946.
Schladetzky KD, Haque TS, Gellman SH. Structural Characterization of Thiocyclophanes That Promote Edge-to-Face Aromatic-Aromatic Geometries. Journal of Organic Chemistry. 1995;60:4108-13.
Rozema D, Gellman SH. Artificial Chaperones: Protein Refolding via Sequential Use of Detergent and Cyclodextrin. Journal of the American Chemical Society. 1995;117:2373-4.
Newcomb LF, Haque TS, Gellman SH. Searching for Minimum Increments of Hydrophobic Collapse: Flexible Dinaphthyl Carboxylates. Journal of the American Chemical Society. 1995;117:6509-19.
D. McQuade T, Barrett DG, Desper JM, Hayashi RK, Gellman SH. Effects of Amphiphilic Topology on Self-Association in Solution, at the Air-Water Interface, and in the Solid State. Journal of the American Chemical Society. 1995;117:4862-9.
Gardner RR, Liang G-B, Gellman SH. An Achiral Dipeptide Mimetic That Promotes β-Hairpin Formation. Journal of the American Chemical Society. 1995;117:3280-1.
Gardner RR, Gellman SH. Evaluation of the Conformation-Directing Effects of Secondary Hydrogen-Bonding Interactions in Flexible Tetrapeptide Analogs. Journal of the American Chemical Society. 1995;117:10411-12.
Desper JM, Gellman SH. STRATEGIES FOR NONMACROCYCLIC POLYTHIOETHER LIGANDS - NEW PENTACOORDINATING ARCHITECTURES. Angewandte Chemie-International Edition. 1994;33:319-321.
Skwierczynski RD, Gellman SH. On the Hydrogen-Bonded Status of 2-Azacyclononanone and 2-Azacyclotridecanone in the Solid State. Journal of Physical Chemistry. 1994;98:3694-6.
Savage PB, Holmgren SK, Gellman SH. Anion and Ion Pair Complexation by a Macrocyclic Phosphine Oxide Disulfoxide. Journal of the American Chemical Society. 1994;116:4069-70.
Newcomb LF, Gellman SH. Aromatic Stacking Interactions in Aqueous Solution: Evidence That neither Classical Hydrophobic Effects nor Dispersion Forces Are Important. Journal of the American Chemical Society. 1994;116:4993-4.
Haque TS, Little JC, Gellman SH. "Mirror image" reverse turns promote β-hairpin formation. Journal of the American Chemical Society. 1994;116:4105-6.
Gallo EA, Gellman SH. Effect of a C-Terminal Cationic Group on the Competition between α-Helical Turn and β-Turn in a Model Depsipeptide. Journal of the American Chemical Society. 1994;116:11560-1.
Dado GP, Gellman SH. Intramolecular Hydrogen Bonding in Derivatives of β-Alanine and γ-Amino Butyric Acid; Model Studies for the Folding of Unnatural Polypeptide Backbones. Journal of the American Chemical Society. 1994;116:1054-62.
Barrett DG, Liang G-B, D. McQuade T, Desper JM, Schladetzky KD, Gellman SH. Synthetic Studies on the 1,6-Methano[10]annulene Skeleton: A New Route That Provides Derivatives Substituted at the Bridge and on the Annulene Ring. Journal of the American Chemical Society. 1994;116:10525-32.
Barrett DG, Gellman SH. Electrophile-induced Berson-Willcott rearrangement of 11-carboxyl-1,6-methano[10]annulene methyl ester. Tetrahedron Letters. 1994;35:2299-300.
Savage PB, Holmgren SK, Gellman SH. Optimization of a phosphine oxide disulfoxide array for multipoint hydrogen bonding to ammonium ions. Journal of the American Chemical Society. 1993;115:7900-1.
Savage PB, Gellman SH. Complexation of hexosammonium ions: evidence for contributions from OH···OH hydrogen bonds in a hydroxylic medium. Journal of the American Chemical Society. 1993;115:10448-9.
Liang GBai, Desper JM, Gellman SH. Effects of backbone rigidification on intramolecular hydrogen bonding in a family of diamides. Journal of the American Chemical Society. 1993;115:925-38.
Gallo EA, Gellman SH. Hydrogen-bond-mediated folding in depsipeptide models of β-turns and α-helical turns. Journal of the American Chemical Society. 1993;115:9774-88.
Desper JM, Vyvyan JR, Mayer MJ, Ochrymowycz LA, Gellman SH. Nickel(II) chelation by three bicyclic tetrathioethers: solution and solid-state data. Inorganic Chemistry. 1993;32:381-2.
Dado GP, Gellman SH. Structural and thermodynamic characterization of temperature-dependent changes in the folding pattern of a synthetic triamide. Journal of the American Chemical Society. 1993;115:4228-45.
Dado GP, Gellman SH. Redox control of secondary structure in a designed peptide. Journal of the American Chemical Society. 1993;115:12609-10.
Barrett DG, Gellman SH. Effects of amphiphile topology on aggregation properties: distinctive behavior of contrafacial amphiphiles. Journal of the American Chemical Society. 1993;115:9343-4.
Gellman SH, Powell DR, Desper JM. An unusual hydrogen bonding pattern in a crystallographically observed β-turn. Tetrahedron LettersTetrahedron Letters. 1992;33:1963-4.
Stein TM, Gellman SH. Synthesis and aggregation properties of a new family of amphiphiles with an unusual headgroup topology. Journal of the American Chemical Society. 1992;114:3943-50.
Savage PB, Desper JM, Gellman SH. Stereoselective oxidation of an eleven-membered heterocycle. Tetrahedron Letters. 1992;33:2107-10.
Liang GBai, Rito CJ, Gellman SH. Variations in the turn-forming characteristics of N-acyl proline units. Biopolymers. 1992;32:293-301.
Liang GBai, Rito CJ, Gellman SH. Thermodynamic analysis of β-turn formation in Pro-Ala, Pro-Gly, and Pro-Val model peptides in methylene chloride. Journal of the American Chemical Society. 1992;114:4440-2.
Gallo EA, Gellman SH. NH···π hydrogen bonding in a norbornenyl diamide. Tetrahedron Letters. 1992;33:7485-8.
Dado GP, Gellman SH. On the use of AM1 calculations for the study of intramolecular hydrogen bonding phenomena in simple amides. Journal of the American Chemical Society. 1992;114:3138-9.
Dado GP, Desper JM, Holmgren SK, Rito CJ, Gellman SH. Effects of covalent modifications on the solid-state folding and packing of N-malonylglycine derivatives. Journal of the American Chemical Society. 1992;114:4834-43.
Barrett DG, Liang GBai, Gellman SH. New synthesis of methano-bridged annulenes: access to highly substituted derivatives. Journal of the American Chemical Society. 1992;114:6915-16.
Liang GBai, Dado GP, Gellman SH. Anatomy of a stable intramolecularly hydrogen bonded folding pattern. Journal of the American Chemical Society. 1991;113:3994-5.
Gellman SH, Dado GP, Liang GBai, Adams BR. Conformation-directing effects of a single intramolecular amide-amide hydrogen bond: variable-temperature NMR and IR studies on a homologous diamide series. Journal of the American Chemical Society. 1991;113:1164-73.
Gellman SH, Dado GP. On the use of molecular mechanics calculations for the study of intramolecular hydrogen bonding phenomena. Tetrahedron Letters. 1991;32:7377-80.
Gellman SH. On the role of methionine residues in the sequence-independent recognition of nonpolar protein surfaces. Biochemistry. 1991;30:6633-6.
Desper JM, Gellman SH, Wolf, Jr. RE, Cooper SR. Enhanced nickel(II) chelation by gem-dimethyl-substituted macrocyclic tetrathioethers. Journal of the American Chemical Society. 1991;113:8663-71.
Desper JM, Gellman SH. Crystallographic evidence for multiple coordinating conformations in a family of macrocyclic chelators. Journal of the American Chemical Society. 1991;113:704-6.
Gellman SH, Adams BR, Dado GP. Temperature-dependent changes in the folding pattern of a simple triamide. Journal of the American Chemical Society. 1990;112:460-1.
Desper JM, Powell DR, Gellman SH. Molecular structure and conformation of two acyclic polythioethers: implications for the design of heavy metal chelators. Journal of the American Chemical Society. 1990;112:4321-4.
Desper JM, Gellman SH. Incremental preorganization of a chelating macrocycle. Journal of the American Chemical Society. 1990;112:6732-4.
Dado GP, Desper JM, Gellman SH. Hydrogen bonding in a family of triamides: conformation-directing effects in solution versus the solid state. Journal of the American Chemical Society. 1990;112:8630-2.
Gellman SH, Adams BR. Intramolecular hydrogen bonding in simple diamides. Tetrahedron Letters. 1989;30:3381-4.
Gellman SH, Petter R, Breslow R. Catalytic hydrolysis of a phosphate triester by tetracoordinated zinc complexes. Journal of the American Chemical Society. 1986;108:2388-94.
Svastits EW, Dawson JH, Breslow R, Gellman SH. Functionalized nitrogen atom transfer catalyzed by cytochrome P-450. Journal of the American Chemical Society. 1985;107:6427-8.
Breslow R, Gellman SH. Intramolecular nitrene carbon-hydrogen insertions mediated by transition-metal complexes as nitrogen analogs of cytochrome P-450 reactions. Journal of the American Chemical Society. 1983;105:6728-9.
Breslow R, Gellman SH. Tolylsulfonylamidation of cyclohexane by a cytochrome P-450 model. J. Chem. Soc., Chem. Commun. 1982;:1400-1.