All Faculty and Research Staff Publications

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Beerman TA, Gawron LS, Shin S, Shen B, McHught MM. C-1027, A Radiomimetic Enediyne Anticancer Drug, Preferentially Targets Hypoxic Cells. Cancer Research. 2009 ;69:593-598.
Van Lanen SG, Lin SJ, Horsman GP, Shen B. Characterization of SgcE6, the flavin reductase component supporting FAD-dependent halogenation and hydroxylation in the biosynthesis of the enediyne antitumor antibiotic C-1027. FEMS Microbiology Letters. 2009 ;300:237-241.
Chen YH, Wendt-Pienkoski E, Rajski SR, Shen B. In Vivo Investigation of the Roles of FdmM and FdmM1 in Fredericamycin Biosynthesis Unveiling a New Family of Oxygenases. Journal of Biological Chemistry. 2009 ;284:24735-24743.
Lim SK, Ju JH, Zazopoulos E, Jiang H, Seo JW, Chen YH, Feng ZY, Rajski SR, Farnet CM, Shen B. iso-Migrastatin, Migrastatin, and Dorrigocin Production in Streptomyces platensis NRRL 18993 Is Governed by a Single Biosynthetic Machinery Featuring an Acyltransferase-less Type I Polyketide Synthase. Journal of Biological Chemistry. 2009 ;284:29746-29756.
Cooke HA, Guenther EL, Luo YG, Shen B, Bruner SD. Molecular Basis of Substrate Promiscuity for the SAM-Dependent O-Methyltransferase NcsB1, Involved in the Biosynthesis of the Enediyne Antitumor Antibiotic Neocarzinostatin. Biochemistry. 2009 ;48:9590-9598.
Adler JT, Cook M, Luo YG, Pitt SC, Ju JH, Li WL, Shen B, Kunnimalaiyaan M, Chen H. Tautomycetin and tautomycin suppress the growth of medullary thyroid cancer cells via inhibition of glycogen synthase kinase-3 beta. Molecular Cancer Therapeutics. 2009 ;8:914-920.
Liu W, Christenson SD, Standage S, Shen B. Biosynthesis of the enediyne antitumor antibiotic C-1027. ScienceScience. 2002 ;297:1170-1173.
Shen B, Du LC, Sanchez C, Edwards DJ, Chen M, Murrell JM. Cloning and characterization of the bleomycin biosynthetic gene cluster from Streptomyces verticillus ATCC15003. Journal of Natural Products. 2002 ;65:422-431.
Kwon HJ, Smith WC, Scharon AJ, Hwang SH, Kurth MJ, Shen B. C-O bond formation by polyketide synthases. ScienceScience. 2002 ;297:1327-1330.
Shen SSP, Shen B, Ong CT, Xu ZT. Collision of uniform soliton trains in asymmetric systems. Dynamics of Continuous Discrete & Impulsive Systems-Series B-Applications & Algorithms. 2002 ;9:131-138.
Shen B, Ormsby AH, Shen C, Dumot JA, Shao YW, Bevins CL, Gramlich TL. Cytokeratin expression patterns in noncardia, intestinal metaplasia-associated gastric adenocarcinoma - Implication for the evaluation of intestinal metaplasia and tumors at the esophagogastric junction. CancerCancer. 2002 ;94:820-831.
Laporte MM, Shen B, Tarczynski MC. Engineering for drought avoidance: expression of maize NADP-malic enzyme in tobacco results in altered stomatal function. Journal of Experimental Botany. 2002 ;53:699-705.
Shen B, Li CJ, Tarczynski MC. High free-methionine and decreased lignin content result from a mutation in the Arabidopsis S-adenosyl-L-methionine synthetase 3 gene. Plant JournalPlant Journal. 2002 ;29:371-380.
Chu RM, Zheng YD, Zhou YG, Han P, Shen B, Gu SL. Impact of dopants in GaN on the formation of two-dimensional electron gas in AlGaN/GaN heterostructure field-effect transistors. Applied Physics a-Materials Science & ProcessingApplied Physics a (Materials Science Processing). 2002 ;75:387-389.
Edgley M, D'Souza A, Moulder G, McKay S, Shen B, Gilchrist E, Moerman D, Barstead R. Improved detection of small deletions in complex pools of DNA - art. no. e52. Nucleic Acids ResearchNucleic Acids Res. 2002 ;30:E52.
Wang F, Zhang R, Tan WS, Xiu XQ, Lu DQ, Gu SL, Shen B, Shi Y, Wu XS, Zheng YD, et al. Influences of mask width, fill factor, HCl addition and C doping on wing tilts in the epitaxial laterally overgrown GaN films by hydride vapor phase epitaxy. Applied Physics Letters. 2002 ;80:4765-4767.
Lee SJ, Ma WY, Shen B. An interactive video delivery and caching system using video summarization. Computer CommunicationsComputer Communications. 2002 ;25:424-435.
Xi DJ, Zheng YD, Chen P, Zhao ZM, Xie SY, Jiang RL, Shen B, Gu SL, Zhang R. Interfacial properties of AlN/Si (111) grown by metal-organic chemical vapour deposition. Chinese Physics Letters. 2002 ;19:543-545.
Shi Y, Shen B, Bu HM, Yuan XL, Gu SL, Han P, Zhang R, Zheng YD. Investigation of switching kinetics of interface traps in metal-oxide-semiconductor-field-effect-transistors with ultra-narrow channels. Japanese Journal of Applied Physics Part 1-Regular Papers Short Notes & Review PapersJapanese Journal of Applied Physics Part 1-Regular Papers Short Notes & Review Papers. 2002 ;41:2363-2366.
Xu Y, Zhu JH, Shen B, Xue J. Investigation on fast determination of trace N-nitrosamines assisted by microwave radiation. Acta Chimica SinicaActa Chimica Sinica. 2002 ;60:876-881.
Shen B, Kwon HJ. Macrotetrolide biosynthesis: A novel type II polyketide synthase. Chemical Record: an Official Publication of the Chemical Society of JapanChemical Record: an Official Publication of the Chemical Society of Japan. 2002 ;2:389-396.
He HY, Williamson RT, Shen B, Graziani EI, Yang HY, Sakya SM, Petersen PJ, Carter GT. Mannopeptimycins, novel antibacterial glycopeptides from Streptomyces hygroscopicus, LL-AC98. Journal of the American Chemical Society. 2002 ;124:9729-9736.
Xi DJ, Zheng YD, Chen P, Zhao ZM, Xie SY, Shen B, Gu SL, Zhang R. Microstructures of AlGaN/AlN/Si (111) grown by metalorganic chemical vapor deposition. Physica Status Solidi A-Applied ResearchPhysica Status Solidi A-Applied Research. 2002 ;191:137-142.
Xie SY, Zheng YD, Chen P, Zhang R, Shen B, Chen H. Optical properties of Mg-implanted GaN. Applied Physics a-Materials Science & ProcessingApplied Physics a (Materials Science Processing). 2002 ;75:363-365.
Ghosh D, Porter E, Shen B, Lee SK, Wilk D, Drazba J, Yadav SP, Crabb JW, Ganz T, Bevins CL. Paneth cell trypsin is the processing enzyme for human defensin-5. Nature ImmunologyNature Immunology. 2002 ;3:583-590.
Jiang RL, Wang JZ, Chen P, Zhao ZM, Mei YF, Shen B, Zhang R, Wu XL, Zheng YD. Photocurrent property of GaN on the Si photodetector with a nearly polycrystalline alpha-Al2O3 buffer layer. Chinese Physics Letters. 2002 ;19:1553-1555.
Zhai JW, Shen B, Yao X, Zhang LY. Preparation and spectral properties of Nd2O3-doped silica-based glasses prepared by the sol-gel process. Ceramics InternationalCeramics International. 2002 ;28:737-740.
Wang L, Luo JR, Yin FX, Shen B, Qin PJ, Wang HZ, Fu P. Recent progress of HT-7 superconducting tokamak PFPS control system. 2002 ;60:421-426.
Inoue A, Shen B. Soft magnetic bulk glassy Fe-B-Si-Nb alloys with high saturation magnetization above 1.5 T. Materials TransactionsMaterials Transactions. 2002 ;43:766-769.
Adhikary DP, Shen B, Fama MED. A study of highwall mining panel stability. International Journal of Rock Mechanics & Mining SciencesInternational Journal of Rock Mechanics & Mining Sciences. 2002 ;39:643-659.