All Faculty and Research Staff Publications

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Bertozzi CR, Kiessling LL. Chemical glycobiology. Science. 2001 ;291:2357-2364.
Gestwicki JE, Strong LE, Borchardt SL, Cairo CW, Schnoes AM, Kiessling LL. Designed potent multivalent chemoattractants for Escherichia coli. Bioorganic & Medicinal Chemistry. 2001 ;9:2387-2393.
Lamanna AC, Gestwicki JE, Adler J, Kiessling LL. Effects of multivalent, chemotactically active, saccharide polymers on bacterial swarmer cell dedifferentiation. Biochemistry. 2001 ;40:8657-8658.
Hinklin RJ, Kiessling LL. Glycosyl sulfonylcarbamates: New glycosyl donors with tunable reactivity. Journal of the American Chemical Society. 2001 ;123:3379-3380.
Nilsson BL, Kiessling LL, Raines RT. High-yielding Staudinger ligation of a phosphinothioester and azide to form a peptide. Organic Letters. 2001 ;3:9-12.
Marlow AL, Kiessling LL. Improved chemical synthesis of UDP-galactofuranose. Organic Letters. 2001 ;3:2517-2519.
Kiessling LL, Young T, Mortell KH. Multivalency in protein-carbohydrate recognition. Glycoscience. 2001 ;2:1817-1861.
Lowe TL, Strzelec A, Kiessling LL, Murphy RM. Structure-function relationships for inhibitors of beta-amyloid toxicity containing the recognition sequence KLVFF. Biochemistry. 2001 ;40:7882-7889.
Steinmann JG, Phillips JH, Sanders WJ, Kiessling LL. Synthesis of cyclic sulfates by halocyclization. Organic Letters. 2001 ;3:3557-3559.
Gestwicki JE, Lamanna AC, Harshey RM, McCarter LL, Kiessling LL, Adler J. Evolutionary conservation of methyl-accepting chemotaxis protein location in Bacteria and Archaea. Journal of Bacteriology. 2000 ;182:6499-6502.
Maki N, Gestwicki JE, Lake EM, Kiessling LL, Adler J. Motility and chemotaxis of filamentous cells of Escherichia coli. Journal of Bacteriology. 2000 ;182:4337-4342.
Kiessling LL, Strong LE, Gestwicki JE. Principles for multivalent ligand design. Annual Reports in Medicinal Chemistry, Vol 35. 2000 ;35:321-330.
Nilsson BL, Kiessling LL, Raines RT. Staudinger ligation: A peptide from a thioester and azide. Organic Letters. 2000 ;2:1939-1941.
Burke SD, Zhao Q, Schuster MC, Kiessling LL. Synergistic formation of soluble lectin clusters by a templated multivalent saccharide ligand. Journal of the American Chemical Society. 2000 ;122:4518-4519.
Gordon EJ, Gestwicki JE, Strong LE, Kiessling LL. Synthesis of end-labeled multivalent ligands for exploring cell-surface-receptor-ligand interactions. Chemistry & Biology. 2000 ;7:9-16.
Kiessling LL, Gestwicki JE, Strong LE. Synthetic multivalent ligands in the exploration of cell-surface interactions. Current Opinion in Chemical Biology. 2000 ;4:696-703.
Gestwicki JE, Strong LE, Kiessling LL. Tuning chemotactic responses with synthetic multivalent ligands. Chemistry & Biology. 2000 ;7:583-591.
Gestwicki JE, Strong LE, Kiessling LL. Visualization of single multivalent receptor-ligand complexes by transmission electron microscopy. Angewandte Chemie-International Edition. 2000 ;39:4567-+.
Hegg EL, Deal KA, Kiessling LL, Burstyn JN. Hydrolysis of double-stranded and single-stranded RNA in hairpin structures by the copper(II) macrocycle Cu( 9 aneN(3))Cl-2. Inorganic Chemistry. 1997 ;36:1715-1718.
Manning DD, Strong LE, Hu X, Beck PJ, Kiessling LL. Neoglycopolymer inhibitors of the selectins. Tetrahedron. 1997 ;53:11937-11952.
Schuster MC, Mortell KH, Hegeman AD, Kiessling LL. Neoglycopolymers produced by aqueous ring-opening metathesis polymerization: Decreasing saccharide density increases activity. Journal of Molecular Catalysis A-Chemical. 1997 ;116:209-216.
Pohl NL, Kiessling LL. Para-chlorobenzyl protecting groups as stabilizers of the glycosidic linkage: Synthesis of the 3'-O-sulfated Lewis X trisaccharide. Tetrahedron Letters. 1997 ;38:6985-6988.
Kurutz JW, Kiessling LL. Solution conformation of Lewis a-derived selectin ligands is unaffected by anionic substituents at the 3'- and 6'-positions. Glycobiology. 1997 ;7:337-347.
Manning DD, Hu X, Beck P, Kiessling LL. Synthesis of sulfated neoglycopolymers: Selective P-selectin inhibitors. Journal of the American Chemical Society. 1997 ;119:3161-3162.
Sanders WJ, Manning DD, Koeller KM, Kiessling LL. Synthesis of sulfated trisaccharide ligands for the selectins. Tetrahedron. 1997 ;53:16391-16422.
Kanai M, Mortell KH, Kiessling LL. Varying the size of multivalent ligands: The dependence of concanavalin a binding on neoglycopolymer length. Journal of the American Chemical Society. 1997 ;119:9931-9932.
Bruning J, Kiessling LL. Convergent synthesis of sulfated bivalent glycopeptides as selectin ligands. Tetrahedron Letters. 1996 ;37:2907-2910.
Weatherman RV, Kiessling LL. Fluorescence anisotropy assays reveal affinities of C- and O-glycosides for concanavalin A. Journal of Organic Chemistry. 1996 ;61:534-538.
Sanders WJ, Katsumoto TR, Bertozzi CR, Rosen SD, Kiessling LL. L-selectin-carbohydrate interactions: Relevant modifications of the Lewis x trisaccharide. Biochemistry. 1996 ;35:14862-14867.
Schueller CM, Manning DD, Kiessling LL. Preparation of (R)-(+)-7-oxabicyclo 2.2.1 hept-5-ene-exo-2-carboxylic acid, a precursor to substrates for the ring opening metathesis polymerization. Tetrahedron Letters. 1996 ;37:8853-8856.
Dantzman CL, Kiessling LL. Reactivity of a 2'-thio nucleotide analog. Journal of the American Chemical Society. 1996 ;118:11715-11719.
Mortell KH, Weatherman RV, Kiessling LL. Recognition specificity of neoglycopolymers prepared by ring-opening metathesis polymerization. Journal of the American Chemical Society. 1996 ;118:2297-2298.
Weatherman RV, Mortell KI, Chervenak M, Kiessling LL, Toone EJ. Specificity of C-glycoside complexation by mannose glucose specific lectins. Biochemistry. 1996 ;35:3619-3624.
Ghanta J, Shen CL, Kiessling LL, Murphy RM. A strategy for designing inhibitors of beta-amyloid toxicity. Journal of Biological Chemistry. 1996 ;271:29525-29528.
Kiessling LL, Pohl NL. Strength in numbers: Non-natural polyvalent carbohydrate derivatives. Chemistry & Biology. 1996 ;3:71-77.
Manning DD, Bertozzi CR, Rosen SD, Kiessling LL. Tin-mediated phosphorylation: Synthesis and selectin binding of a phospho Lewis a analog. Tetrahedron Letters. 1996 ;37:1953-1956.