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Tao Liu, Ph.D.
Postdoctoral Fellow, School of
Pharmacy, UW-Madison
Email:
tliu8@wisc.edu |
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2002-2006 |
Ph.D.,
Pharm. Sci.,
University of Kentucky |
1996-1999 |
M.S., Biochemistry, Shandong Normal
University, China |
1992-1996 |
B.S.,
Biology, Shandong Normal University, China |
HONORS & AWARDS
Outstanding Academic Achievement (2001-2002), East
Tennessee State University
Peter G. Glavinos, Jr. Graduate Scholarship (2004),
University of Kentucky
Graduate School Academic Year fellowship (2005),
University of Kentucky
Travel award (2006), The 20th National Medicinal
Chemistry Symposium, Seattle
RESEARCH PRESENTATIONS
I. Carsten Fischer, Tao Liu, Andrew
McCormick, Fredilyn Lipata and Jürgen
Rohr (2003). The biosynthetic gene
cluster and biosynthetic key steps of
photoactivatable antitumor drug
gilvocarcin V. AACR-NCI-EORTC
International Conference ‘Molecular
Targets and Cancer Therapeutics’ Boston,
MA
II. Tao Liu, Carsten Fischer, Lili Zhu,
Lisa Greenwell, Jürgen Rohr (2004)
Elucidation of the biosynthetic pathway
of gilvocarcin V and generation of novel
analogues through combinatorial
biosynthesis. 56th Southeast Regional
Meeting of American Chemical Society
III. Tao Liu, Lili Zhu, Madan Kharel,
Carsten Fischer, Cynthia Mattingly, Val
R. Adams, and Jürgen Rohr (2005).
Derivatives of the photoactivatable
antitumor drug gilvocarcin V by
combinatorial biosynthesis. AACR Annual
meeting, San Dieago, CA
IV. Tao Liu, Jose. A. Salas, Carmen
Mendez and Jürgen Rohr (2005). Novel
Analogues of the anticancer drug
gilvocarcin V by combinatorial
biosynthesis. AAPS Annual Meeting and
Exposition, Nashville, TN
V. Madan Kharel, Tao Liu, Lili Zhu, and
Jürgen Rohr (2005). Post-PKS oxidative
reactions involved in jadomycin and
gilvocarcin biosynthesis. AAPS Annual
Meeting and Exposition, Nashville, TN
VI. Tao Liu and Jürgen Rohr (2006).
Novel gilvocarcin V derivatives by
combinatorial biosynthesis
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1. Bodan Ostash, Uwe Rix, Lily Remsing Rix,
Tao Liu, F Lombo, Andriy Luzhetskyy, Gromyko O, Chenchen
Wang, Alfredo F. Brana, Carmen Mendez, Jose. A. Salas, Viktor
Fedorenko, Jurgen Rohr (2004) Generation of new landomycins by
combinatorial biosynthetic manipulation of the LndGT4 gene of
the landomycin E cluster in S. globisporus. Chem Biol.
11(4):547-55.
2. Andriy Luzhetskyy, Tao Liu, Marta Fedoryshyn, Bohdan
Ostash, Viktor Fedorenko, Jürgen Rohr, Andreas Bechthold (2004).
Function of lanGT3, a glycosyltransferase gene involved in
landomycin A biosynthesis. Chembiochem. 5(11):1567-70.
3. Tao Liu, Carsten Fischer, Claus Beninga, and Jürgen
Rohr (2004). Oxidative rearrangement processes in the
biosynthesis of gilvocarcin V. J. Am. Chem. Soc.
126(39):12262-3.
4. Tao Liu, Madan Kharel, Carsten Fischer, Andrew
McCormick and Jürgen Rohr. Inactivation of gilGT encoding a C-Glycosyltransferase
and gilOIII encoding a p450 monooxygenase, shed light into the
biosynthetic pathway of Gilvocarcin V. ChemBioChem, 2006, 7(7),
1070
5. Tao Liu and Jürgen Rohr. Generation of gilvocarcins
with novel fucofuranose by inactivation of oxidoreductse GilU in
the biosynthesis of gilvocarcin. in preparation
6. Tao Liu, Carmen Mendez, Jose. A. Salas and Jürgen
Rohr. Altering glycosylation patterns of anticancer agent
gilvocarcins by combinatorial biosynthesis. In preparation.
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