chrismiddleton
Postdoctoral Research Associate
with Prof. Martin T. Zanni
Department of Chemistry
University of Wisconsin - Madison
ctmiddle@chem.wisc.edu

researcherid.com/rid/A-6365-2008
curriculum vitae (pdf)
research

Current research includes the study of the misfolding and aggregation of human islet amyloid polypeptide (amylin), processes thought to lead to type 2 diabetes, using isotope labeling and two-dimensional infrared spectroscopy.

Read more about my most recent paper in this article from Chemical & Engineering News.

Listen to me talk about our research on Wisconsin Life, Wisconsin Public Radio

Check out this video about our research, produced by the University of Wisconsin-Madison:

recent publications
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Two-dimensional infrared spectroscopy reveals the complex behaviour of an amyloid fibril inhibitor
Chris T. Middleton, Peter Marek, Ping Cao, Chi-cheng Chiu, Sadanand Singh, Ann Marie Woys, Juan J. de Pablo, Daniel P. Raleigh & Martin T. Zanni
Nature Chemistry
2012
4
355-360
Utilizing Lifetimes to Suppress Random Coil Features in 2D IR Spectra of Peptides
Chris T. Middleton, Lauren E. Buchanan, Emily B. Dunkelberger, Martin T. Zanni
Journal of Physical Chemistry Letters
2011
2
2357-2361
2DIR Spectroscopy of Human Amylin Fibrils Reflects Stable β-Sheet Structure
Lu Wang, Chris T. Middleton, Sadanand Singh, Allam S. Reddy, Ann M. Woys, David B. Strasfeld, Peter Marek, Daniel P. Raleigh, Juan J. de Pablo, Martin T. Zanni, James L. Skinner
Journal of the American Chemical Society
2011
133
16062-16071
view all publications
past research

Research with Prof. Bern Kohler, at Ohio State University (now at Montana State University), involved the time-resolved study of the photophysics of DNA bases and polymers; ground-state vibrational cooling and excited-state dynamics using femtosecond transient absorption in the UV, visible and mid-IR.

Research with Prof. Bruce S. Hudson, at Syracuse University, involved the study of the vibrational properties of organic moleucles through inelastic neutron scattering spectroscopy and computational methods.

Research with Prof. Shaul Mukamel, at the University of Rochester (now at the University of California, Irvine), involved theoretical study of excitonic coupling in light harvesting complexes using the Collective Electronic Oscillators approach.

other

citation search
A fast way to find articles from the journal name, volume and start page.

energy unit conversion tool
A quick script to do some energy unit conversions relevent to spectroscopy.

photos
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