chrismiddleton
Postdoctoral Research Associate
with Prof. Martin T. Zanni
Department of Chemistry
University of Wisconsin - Madison
ctmiddle@chem.wisc.edu

researcherid.com/rid/A-6365-2008
curriculum vitae (pdf)
research

Current research includes the study of the misfolding and aggregation of human islet amyloid polypeptide (amylin), processes thought to lead to type II diabetes, using isotope labeling and two dimensional infrared spectroscopy.

recent publications
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Utilizing Lifetimes to Suppress Random Coil Features in 2D IR Spectra of Peptides
Chris T. Middleton, Lauren E. Buchanan, Emily B. Dunkelberger, Martin T. Zanni
Journal of Physical Chemistry Letters
2011
2
2357-2361
2DIR Spectroscopy of Human Amylin Fibrils Reflects Stable β-Sheet Structure
Lu Wang, Chris T. Middleton, Sadanand Singh, Allam S. Reddy, Ann M. Woys, David B. Strasfeld, Peter Marek, Daniel P. Raleigh, Juan J. de Pablo, Martin T. Zanni, James L. Skinner
Journal of the American Chemical Society
2011
133
16062-16071
Residue-specific structural kinetics of proteins through the union of isotope labeling, mid-IR pulse shaping, and coherent 2D IR spectroscopy
Chris T. Middleton, Ann Marie Woys, Sudipta S. Mukherjee, Martin T. Zanni
Methods
2010
50
12-22
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past research

Research with Prof. Bern Kohler, at Ohio State University (now at Montana State University), involved the time-resolved study of the photophysics of DNA bases and polymers; ground-state vibrational cooling and excited-state dynamics using femtosecond transient absorption in the UV, visible and mid-IR.

Research with Prof. Bruce S. Hudson, at Syracuse University, involved the study of the vibrational properties of organic moleucles through inelastic neutron scattering spectroscopy and computational methods.

Research with Prof. Shaul Mukamel, at the University of Rochester (now at the University of California, Irvine), involved theoretical study of excitonic coupling in light harvesting complexes using the Collective Electronic Oscillators approach.

other

citation search
A fast way to find articles from the journal name, volume and start page.

energy unit conversion tool
A quick script to do some energy unit conversions relevent to spectroscopy.

photos
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