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Dr. Nese KURT YILMAZ

Home Town:
Kirklareli, Turkey

Position in lab:
Assistant Scientist

Email:
kurt@chem.wisc.edu

Started in lab:
Summer, 2002

Previous education:
PhD, Chemical Engineering, Bogazici University, Istanbul, Turkey

Research Interests:
Folding/misfolding of proteins and interactions with Hsp70 chaperones
and
Mechanisms of protein folding and misfolding, impact of chain truncation on polypeptide conformation and folding kinetics

Selected publications:
Kurt, Cavagnero, S. "Nonnative Helical Motif in a Chaperone-Bound Protein Fragment" Biophys. J. 94, 48-50 (2008).

Eun, Y.-J., Kurt, N., Sekhar, A., Cavagnero, S. "Thermodynamic and Kinetic Characterization of ApoHmpH, a Fast-Folding Bacterial Globin" J. Mol. Biol. 376, 879-897 (2008).

Cavagnero S and Kurt N "Folding and Misfolding as a Function of Polypeptide Chain Elongation: Conformational Trends and Implications for Intracellular Events" in Misbehaving Proteins: Protein (Mis)Folding, Aggregation and Stability, editors RM Murphy and AM Tsai, Springer, ISBN: 0387305084 (2006).

Kurt, N., Rajagopalan, S., Cavagnero, S. 'Effect of Hsp70 Chaperone on the Folding and Misfolding of Polypeptides Modeling an Elongating Protein Chain', J. Mol. Bio., Vol. 355, Iss.4, 809-820 (2006).

Chow, C.K., Kurt, N., Murphy, R.M., Cavagnero, S. 'Structural Characterization of Apomyoglobin Self-Associated Species in Aqueous Buffer and Urea Solution', Biophys. J., Vol. 90, 298-309 (2006).

Kurt, N., Cavagnero, S. 'The Burial of Solvent-Accessible Surface Area is a Predictor of Polypeptide Folding and Misfolding as a Function of Chain Elongation', J. Am. Chem. Soc., Vol. 127, Iss. 45, 15690-15691 (2005).

Kurt N, Haliloglu T and Schiffer CA "Structure-Based Prediction of Potential Binding and Non-Binding Peptides to HIVProtease" Biophysical Journal Vol. 85, Iss. 2, 853-863 (2003).

Kurt N, Scott WRP, Haliloglu T and Schiffer CA "Cooperative Fluctuations of Unliganded and Substrate-Bound HIV-1 Protease: A Structure-Based Analysis on a Variety of Conformations from Crystallography and Molecular Dynamics Simulations" Proteins: Structure, Function and Genetics, Vol. 51, Iss. 3, 409-422 (2003).