Buchberger AR, DeLaney K, Johnson J, Li LJ. Mass Spectrometry Imaging: A Review of Emerging Advancements and Future Insights. Analytical Chemistry. 2018;90:240-265.
Chen BM, Lietz CB, Li LJ. Coupling matrix-assisted ionization with high resolution mass spectrometry and electron transfer dissociation to characterize intact proteins and post-translational modifications. Analytical and Bioanalytical Chemistry. 2018;410:1007-1017.
Chen BM, Zhong XF, Feng Y, Snovida S, Xu M, Rogers J, et al.. Targeted MultiNotch MS3 Approach for Relative Quantification of N-Glycans Using Multiplexed Carbonyl-Reactive Isobaric Tags. Analytical Chemistry. 2018;90:1129-1135.
Chen BM, Ouyang CZ, Tian ZC, Xu M, Li LJ. A high resolution atmospheric pressure matrix-assisted laser desorption/ionization-quadrupole-orbitrap MS platform enables in situ analysis of biomolecules by multi-mode ionization and acquisition. Analytica Chimica Acta. 2018;1007:16-25.
Stallcop LE, Alvarez-Garcia YR, Reyes-Ramos AM, Ramos-Cruz KP, Morgan MM, Shi YT, et al.. Razor-printed sticker microdevices for cell-based applications. Lab on a Chip. 2018;18:451-462.
DeLaney K, Buchberger AR, Atkinson L, Grunder S, Mousley A, Li LJ. New techniques, applications and perspectives in neuropeptide research. Journal of Experimental Biology. 2018;221.
Chen ZW, Glover MS, Li LJ. Recent advances in ion mobility-mass spectrometry for improved structural characterization of glycans and glycoconjugates. Current Opinion in Chemical Biology. 2018;42:1-8.
Yao M, Chen BM, Zhao WP, Mehl JT, Li LJ, Zhu MS. LC-MS Differential Analysis for Fast and Sensitive Determination of Biotransformation of Therapeutic Proteins. Drug Metabolism and Disposition. 2018;46:451-457.
Pang XQ, Jia CX, Chen ZW, Li LJ. Structural Characterization of Monomers and Oligomers of D-Amino Acid-Containing Peptides Using T-Wave Ion Mobility Mass Spectrometry. Journal of the American Society for Mass Spectrometry. 2017;28:110-118.
Hao L, Johnson J, Lietz CB, Buchberger A, Frost D, Kao WJ, et al.. Mass Defect-Based N,N-Dimethyl Leucine Labels for Quantitative Proteomics and Amine Metabolomics of Pancreatic Cancer Cells. Analytical Chemistry. 2017;89:1138-1146.
Zhu YC, Takayama T, Wang BW, Kent A, Zhang MX, Binder BYK, et al.. Restenosis Inhibition and Re-differentiation of TGF beta/Smad3-activated Smooth Muscle Cells by Resveratrol. Scientific Reports. 2017;7.
Yu Q, Shi XD, Feng Y, Kent KC, Li LJ. Improving data quality and preserving HCD-generated reporter ions with EThcD for isobaric tag-based quantitative proteomics and proteome-wide PTM studies. Analytica Chimica Acta. 2017;968:40-49.
Zhang XM, Jiang S, Mitok KA, Li LJ, Attie AD, Martin TFJ. BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells. Journal of Cell Biology. 2017;216:2151-2166.
Yu Q, Wang B, Chen Z, Urabe G, Glover MS, Shi X, et al.. Electron-Transfer/Higher-Energy Collision Dissociation (EThcD)-Enabled Intact Glycopeptide/Glycoproteome Characterization. Journal of the American Society for Mass Spectrometry. 2017;:Ahead of Print.
Chen Z, Zhong X, Tie C, Chen B, Zhang X, Li LJ. Development of a hydrophilic interaction liquid chromatography coupled with matrix-assisted laser desorption/ionization-mass spectrometric imaging platform for N-glycan relative quantitation using stable-isotope labeled hydrazide reagents. Analytical and Bioanalytical Chemistry. 2017;409:4437-4447.
Gemperline E, Horn HA, DeLaney K, Currie CR, Li LJ. Imaging with Mass Spectrometry of Bacteria on the Exoskeleton of Fungus-Growing Ants. ACS Chemical Biology. 2017;12:1980-1985.
Yu Q, Canales A, Glover MS, Das R, Shi XD, Liu Y, et al.. Targeted Mass Spectrometry Approach Enabled Discovery of O-Glycosylated Insulin and Related Signaling Peptides in Mouse and Human Pancreatic Islets. Analytical Chemistry. 2017;89:9184-9191.
Chen RB, Liu Y, Zhuang H, Yang BC, Hei KW, Xiao MM, et al.. Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation. Nucleic Acids Research. 2017;45:9947-9959.
Ye H, Wang JX, Tian ZC, Ma FF, Dowell J, Bremer Q, et al.. Quantitative Mass Spectrometry Reveals Food Intake-Induced Neuropeptide Level Changes in Rat Brain: Functional Assessment of Selected Neuropeptides as Feeding Regulators. Molecular & Cellular Proteomics. 2017;16:1922-1937.
Cheloha RW, Chen BM, Kumar NN, Watanabe T, Thorne RG, Li LJ, et al.. Development of Potent, Protease-Resistant Agonists of the Parathyroid Hormone Receptor with Broad beta Residue Distribution. Journal of Medicinal Chemistry. 2017;60:8816-8833.
Fouque KJD, Garabedian A, Porter J, Baird M, Pang XQ, Williams TD, et al.. Fast and Effective Ion Mobility-Mass Spectrometry Separation of D-Amino-Acid-Containing Peptides. Analytical Chemistry. 2017;89:11787-11794.
Liu FB, Ma FF, Wang YY, Hao L, Zeng H, Jia CX, et al.. PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis. Nature Cell Biology. 2017;19:1358-+.
Ma M, Zhao XY, Chen S, Zhao YY, Yang L, Feng Y, et al.. Strategy Based on Deglycosylation, Multiprotease, and Hydrophilic Interaction Chromatography for Large-Scale Profiling of Protein Methylation. Analytical Chemistry. 2017;89:12909-12917.
Adnani N, Chevrette MG, Adibhatla SN, Zhang F, Yu Q, Braun DR, et al.. Coculture of Marine Invertebrate-Associated Bacteria and Interdisciplinary Technologies Enable Biosynthesis and Discovery of a New Antibiotic, Keyicin. ACS Chemical Biology. 2017;12:3093-3102.
Frost DC, Buchberger AR, Li LJ. Mass Defect-Based Dimethyl Pyrimidinyl Ornithine (DiPyrO) Tags for Multiplex Quantitative Proteomics. Analytical Chemistry. 2017;89:10798-10805.
Hu CW, Worth M, Fan DC, Li BB, Li H, Lu L, et al.. Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase. Nature Chemical Biology. 2017;13:1267-+.
Lu JF, Zhong XF, Liu HS, Hao L, Huang CTL, Sherafat MA, et al.. Generation of serotonin neurons from human pluripotent stem cells. Nature Biotechnology. 2016;34:89-94.
Keil KP, Abler LL, Altmann HM, Bushman W, Marker PC, Li LJ, et al.. Influence of animal husbandry practices on void spot assay outcomes in C57BL/6J male mice. Neurourology and Urodynamics. 2016;35:192-198.
Chen BM, Lietz CB, Ouyang CZ, Zhong XF, Xu M, Li LJ. Matrix-assisted ionization vacuum for protein detection, fragmentation and PTM analysis on a high resolution linear ion trap-orbitrap platform. Analytica Chimica Acta. 2016;916:52-59.
Gemperline E, Keller C, Li LJ. Mass Spectrometry in Plant-omics. Analytical Chemistry. 2016;88:3422-3434.
Thomas S, Hao L, Ricke WA, Li LJ. Biomarker discovery in mass spectrometry-based urinary proteomics. Proteomics Clinical Applications. 2016;10:358-370.
Zhong XF, Hao L, Lu JF, Ye H, Zhang SC, Li LJ. Quantitative analysis of serotonin secreted by human embryonic stem cells-derived serotonergic neurons via pH-mediated online stacking-CE-ESI-MRM. Electrophoresis. 2016;37:1027-1030.
Jiang S, Liang ZD, Hao L, Li LJ. Investigation of signaling molecules and metabolites found in crustacean hemolymph via in vivo microdialysis using a multifaceted mass spectrometric platform. Electrophoresis. 2016;37:1031-1038.
Chesney AR, Booth CJ, Lietz CB, Li LJ, Pedersen JA. Peroxymonosulfate Rapidly Inactivates the Disease-Associated Prion Protein. Environmental Science & Technology. 2016;50:7095-7105.
Hullinger R, Li M, Wang JX, Peng YJ, Dowell JA, Bomba-Warczak E, et al.. Increased expression of AT-1/SLC33A1 causes an autistic-like phenotype in mice by affecting dendritic branching and spine formation. Journal of Experimental Medicine. 2016;213:1267-1284.
Hao L, Greer T, Page D, Shi YT, Vezina CM, Macoska JA, et al.. In-Depth Characterization and Validation of Human Urine Metabolomes Reveal Novel Metabolic Signatures of Lower Urinary Tract Symptoms. Scientific Reports. 2016;6.
Wang JX, Cunningham R, Zetterberg H, Asthana S, Carlsson C, Okonkwo O, et al.. Label-free quantitative comparison of cerebrospinal fluid glycoproteins and endogenous peptides in subjects with Alzheimer's disease, mild cognitive impairment, and healthy individuals. Proteomics Clinical Applications. 2016;10:1225-1241.
Gemperline E, Keller C, Jayaraman D, Maeda J, Sussman MR, Ane JM, et al.. Examination of Endogenous Peptides in Medicago truncatula Using Mass Spectrometry Imaging. Journal of Proteome Research. 2016;15:4403-4411.
Yu Q, Shi X, Greer T, Lietz CB, K. Kent C, Li LJ. Evaluation and Application of Dimethylated Amino Acids as Isobaric Tags for Quantitative Proteomics of the TGF-β/Smad3 Signaling Pathway. Journal of Proteome Research. 2016;15:3420-3431.
Jia C, Lietz CB, Yu Q, Li LJ. Site-specific Localization of D-Amino Acids in Bioactive Peptides by Ion Mobility Spectrometry. Neuromethods. 2016;114:43-53.
Lietz CB, Chen Z, Son CYun, Pang X, Cui Q, Li LJ. Multiple gas-phase conformations of proline-containing peptides: is it always cis/trans isomerization?. Analyst. 2016;141:4863-4869.
Hao L, Zhong XF, Greer T, Ye H, Li LJ. Relative quantification of amine-containing metabolites using isobaric N,N-dimethyl leucine (DiLeu) reagents via LC-ESI-MS/MS and CE-ESI-MS/MS. Analyst. 2015;140:467-475.
Greer T, Lietz CB, Xiang F, Li LJ. Novel isotopic N,N-Dimethyl Leucine (iDiLeu) Reagents Enable Absolute Quantification of Peptides and Proteins Using a Standard Curve Approach. Journal of the American Society for Mass Spectrometry. 2015;26:107-119.
Gemperline E, Jayaraman D, Maeda J, Ane JM, Li LJ. Multifaceted Investigation of Metabolites During Nitrogen Fixation in Medicago via High Resolution MALDI-MS Imaging and ESI-MS. Journal of the American Society for Mass Spectrometry. 2015;26:149-158.
Schmerberg CM, Liang ZD, Li LJ. Data-Independent MS/MS Quantification of Neuropeptides for Determination of Putative Feeding-Related Neurohormones in Microdialysate. ACS Chemical Neuroscience. 2015;6:174-180.
Frost DC, Greer T, Li LJ. High-Resolution Enabled 12-Plex DiLeu Isobaric Tags for Quantitative Proteomics. Analytical Chemistry. 2015;87:1646-1654.
Frost DC, Greer T, Xiang F, Liang ZD, Li LJ. Development and characterization of novel 8-plex DiLeu isobaric labels for quantitative proteomics and peptidomics. Rapid Communications in Mass Spectrometry. 2015;29:1115-1124.
Liang ZD, Schmerberg CM, Li LJ. Mass spectrometric measurement of neuropeptide secretion in the crab, Cancer borealis, by in vivo microdialysis. Analyst. 2015;140:3803-3813.
Gushue D, Herbst A, Li LJ, McKenzie D, Aiken J. Pre-clinical biomarkers of prion infection. Prion. 2015;9:S51-S52.
Ouyang CZ, Liang ZD, Li LJ. Mass spectrometric analysis of spatio-temporal dynamics of crustacean neuropeptides. Biochimica Et Biophysica Acta-Proteins and Proteomics. 2015;1854:798-811.
Cheng J, Li WX, Kang B, Zhou YW, Song JS, Dan SS, et al.. Tryptophan derivatives regulate the transcription of Oct4 in stem-like cancer cells. Nature Communications. 2015;6.
Zhong XF, Chen ZW, Snovida S, Liu Y, Rogers JC, Li LJ. Capillary Electrophoresis-Electrospray Ionization-Mass Spectrometry for Quantitative Analysis of Glycans Labeled with Multiplex Carbonyl-Reactive Tandem Mass Tags. Analytical Chemistry. 2015;87:6527-6534.
Greer T, Hao L, Nechyporenko A, Lee S, Vezina CM, Ricke WA, et al.. Custom 4-Plex DiLeu Isobaric Labels Enable Relative Quantification of Urinary Proteins in Men with Lower Urinary Tract Symptoms (LUTS). Plos One. 2015;10.
Jiang S, Zhang ZC, Li LJ. A one-step preparation method of monolithic enzyme reactor for highly efficient sample preparation coupled to mass spectrometry-based proteomics studies. Journal of Chromatography A. 2015;1412:75-81.
Ye H, Wang JX, Zhang ZC, Jia CX, Schmerberg C, Catherman AD, et al.. Defining the Neuropeptidome of the Spiny Lobster Panulirus interruptus Brain Using a Multidimensional Mass Spectrometry-Based Platform. Journal of Proteome Research. 2015;14:4776-4791.
Ouyang CZ, Chen BM, Li LJ. High Throughput In Situ DDA Analysis of Neuropeptides by Coupling Novel Multiplex Mass Spectrometric Imaging (MSI) with Gas-Phase Fractionation. Journal of the American Society for Mass Spectrometry. 2015;26:1992-2001.
Zhang YZ, Buchberger A, Muthuvel G, Li LJ. Expression and distribution of neuropeptides in the nervous system of the crab Carcinus maenas and their roles in environmental stress. Proteomics. 2015;15:3969-3979.
Cohen HCaitlin, Frost DC, Lieberthal TJacob, Li LJ, W. Kao J. Biomaterials differentially regulate Src kinases and phosphoinositide 3-kinase-γ in polymorphonuclear leukocyte primary and tertiary granule release. Biomaterials. 2015;50:47-55.
Buchberger A, Yu Q, Li LJ. Advances in Mass Spectrometric Tools for Probing Neuropeptides. Annual Review of Analytical Chemistry. 2015;8:485-509.
Frost DC, Li LJ. Recent Advances in Mass Spectrometry-Based Glycoproteomics. In: Donev R. 2014. pp. 71-123.
Zhong XF, Zhang ZC, Jiang S, Li LJ. Recent advances in coupling capillary electrophoresis- based separation techniques to ESI and MALDI-MS. Electrophoresis. 2014;35:1214-1225.
Ye H, Mandal R, Catherman A, Thomas PM, Kelleher NL, Ikonomidou C, et al.. Top-Down Proteomics with Mass Spectrometry Imaging: A Pilot Study towards Discovery of Biomarkers for Neurodevelopmental Disorders. Plos One. 2014;9.
Sturm RM, Lietz CB, Li LJ. Improved isobaric tandem mass tag quantification by ion mobility mass spectrometry. Rapid Communications in Mass Spectrometry. 2014;28:1051-1060.
Jia CX, Lietz CB, Yu Q, Li LJ. Site-Specific Characterization of D-Amino Acid Containing Peptide Epimers by Ion Mobility Spectrometry. Analytical Chemistry. 2014;86:2972-2981.
Gushue DL, Herbst A, Li LJ, McKenzie D, Aiken J. Identification of ante-mortem prion disease biomarkers. Prion. 2014;8:78-78.
Gemperline E, Laha K, Scarlett CO, Pearce RA, Li LJ. Measurement of NMDA receptor antagonist, CPP, in mouse plasma and brain tissue following systemic administration using ion-pair LC-MS/MS. Analytical Methods. 2014;6:6389-6396.
Katsumura KR, Yang CX, Boyer ME, Li LJ, Bresnick EH. Molecular basis of crosstalk between oncogenic Ras and the master regulator of hematopoiesis GATA-2. Embo Reports. 2014;15:938-947.
Gemperline E, Rawson S, Li LJ. Optimization and Comparison of Multiple MALDI Matrix Application Methods for Small Molecule Mass Spectrometric Imaging. Analytical Chemistry. 2014;86:10030-10035.
Lietz CB, Yu Q, Li LJ. Large-Scale Collision Cross-Section Profiling on a Traveling Wave Ion Mobility Mass Spectrometer. Journal of the American Society for Mass Spectrometry. 2014;25:2009-2019.
Yang CX, Zhong XF, Li LJ. Recent advances in enrichment and separation strategies for mass spectrometry-based phosphoproteomics. Electrophoresis. 2014;35:3418-3429.
Gemperline E, Li LJ. MALDI-Mass Spectrometric Imaging for the Investigation of Metabolites in Medicago truncatula Root Nodules. Jove-Journal of Visualized Experiments. 2014;.
Jia CX, Yu Q, Wang JX, Li LJ. Qualitative and quantitative top-down mass spectral analysis of crustacean hyperglycemic hormones in response to feeding. Proteomics. 2014;14:1185-1194.
Jia CX, Wu Z, Lietz CB, Liang ZD, Cui Q, Li LJ. Gas-Phase Ion Isomer Analysis Reveals the Mechanism of Peptide Sequence Scrambling. Analytical Chemistry. 2014;86:2917-2924.
Gemperline E, Chen BM, Li LJ. Challenges and recent advances in mass spectrometric imaging of neurotransmitters. Bioanalysis. 2014;6:525-540.
Chen RB, Ouyang CZ, Xiao MM, Li LJ. In situ identification and mapping of neuropeptides from the stomatogastric nervous system of Cancer borealis. Rapid Communications in Mass Spectrometry. 2014;28:2437-2444.
Chen BM, Lietz CB, Li LJ. In Situ Characterization of Proteins Using Laserspray Ionization on a High-Performance MALDI-LTQ-Orbitrap Mass Spectrometer. Journal of the American Society for Mass Spectrometry. 2014;25:2177-2180.
Chen RB, Xiao MM, Buchberger A, Li LJ. Quantitative Neuropeptidomics Study of the Effects of Temperature Change in the Crab Cancer borealis. Journal of Proteome Research. 2014;13:5767-5776.
Zhang ZC, Kuang J, Li LJ. Liquid chromatography-matrix-assisted laser desorption/ionization mass spectrometric imaging with sprayed matrix for improved sensitivity, reproducibility and quantitation. Analyst. 2013;138:6600-6606.
Zhang ZC, Jiang S, Li LJ. Semi-automated liquid chromatography-mass spectrometric imaging platform for enhanced detection and improved data analysis of complex peptides. Journal of Chromatography A. 2013;1293:44-50.
Zhang J, Lanham KA, Heideman W, Peterson RE, Li LJ. Statistically Enhanced Spectral Counting Approach to TCDD Cardiac Toxicity in the Adult Zebrafish Heart. Journal of Proteome Research. 2013;12:3093-3103.
Ye H, Wang JX, Greer T, Strupat K, Li LJ. Visualizing Neurotransmitters and Metabolites in the Central Nervous System by High Resolution and High Accuracy Mass Spectrometric Imaging. ACS Chemical Neuroscience. 2013;4:1049-1056.
Ye H, Hui LM, Kellersberger K, Li LJ. Mapping of Neuropeptides in the Crustacean Stomatogastric Nervous System by Imaging Mass Spectrometry. Journal of the American Society for Mass Spectrometry. 2013;24:134-147.
Ye H, Gemperline E, Venkateshwaran M, Chen RB, Delaux PM, Howes-Podoll M, et al.. MALDI mass spectrometry-assisted molecular imaging of metabolites during nitrogen fixation in the Medicago truncatula-Sinorhizobium meliloti symbiosis. Plant Journal. 2013;75:130-145.
Ye H, Gemperline E, Li LJ. A vision for better health: Mass spectrometry imaging for clinical diagnostics. Clinica Chimica Acta. 2013;420:11-22.
Sturm RM, Greer T, Woodards N, Gemperline E, Li LJ. Mass Spectrometric Evaluation of Neuropeptidomic Profiles upon Heat Stabilization Treatment of Neuroendocrine Tissues in Crustaceans. Journal of Proteome Research. 2013;12:743-752.
Sturm RM, Greer T, Chen RB, Hensen B, Li LJ. Comparison of NIMS and MALDI platforms for neuropeptide and lipid mass spectrometric imaging in C. borealis brain tissue. Analytical Methods. 2013;5:1623-1628.
Schmerberg CM, Li LJ. Function-Driven Discovery of Neuropeptides with Mass Spectrometry-Based Tools. Protein and Peptide Letters. 2013;20:681-694.
Schmerberg CM, Li LJ. Mass Spectrometric Detection of Neuropeptides Using Affinity-Enhanced Microdialysis with Antibody-Coated Magnetic Nanoparticles. Analytical Chemistry. 2013;85:915-922.
Rodgers EW, Krenz WD, Jiang XY, Li LJ, Baro DJ. Dopaminergic tone regulates transient potassium current maximal conductance through a translational mechanism requiring D1Rs, cAMP/PKA, Erk and mTOR
. Bmc Neuroscience. 2013;14.
Ma D, Cao WF, Kapur A, Felder M, Scarlett CO, Patankar MS, et al.. Differential expression of proteins in naive and IL-2 stimulated primary human NK cells identified by global proteomic analysis. Journal of Proteomics. 2013;91:151-163.
Lietz CB, Gemperline E, Li LJ. Qualitative and quantitative mass spectrometry imaging of drugs and metabolites. Advanced Drug Delivery Reviews. 2013;65:1074-1085.
Jia CX, Lietz CB, Ye H, Hui LM, Yu Q, Yoo S, et al.. A multi-scale strategy for discovery of novel endogenous neuropeptides in the crustacean nervous system. Journal of Proteomics. 2013;91:1-12.
Hui LM, D'Andrea BT, Jia CX, Liang ZD, Christie AE, Li LJ. Mass spectrometric characterization of the neuropeptidome of the ghost crab Ocypode ceratophthalma (Brachyura, Ocypodidae). General and Comparative Endocrinology. 2013;184:22-34.
Cunningham R, Jany P, Messing A, Li LJ. Protein Changes in Immunodepleted Cerebrospinal Fluid from a Transgenic Mouse Model of Alexander Disease Detected Using Mass Spectrometry. Journal of Proteome Research. 2013;12:719-728.
Zhang ZC, Wang JH, Hui LM, Li LJ. Poly(glycidyl methacrylate-divinylbenzene) based immobilized pH gradient capillary isoelectric focusing coupling with MALDI mass spectrometry for enhanced neuropeptide analysis. Electrophoresis. 2012;33:661-665.
Zhang ZC, Jia CX, Li LJ. Neuropeptide analysis with liquid chromatography-capillary electrophoresis-mass spectrometric imaging. Journal of Separation Science. 2012;35:1779-1784.
Ma D, Li LJ. Searching for reliable premortem protein biomarkers for prion diseases: progress and challenges to date. Expert Review of Proteomics. 2012;9:267-280.
Jiang XY, Chen RB, Wang JH, Metzler A, Tlusty M, Li LJ. Mass Spectral Charting of Neuropeptidomic Expression in the Stomatogastric Ganglion at Multiple Developmental Stages of the Lobster Homarus americanus. ACS Chemical Neuroscience. 2012;3:439-450.
Jia CX, Hui LM, Cao WF, Lietz CB, Jiang XY, Chen RB, et al.. High-definition De Novo Sequencing of Crustacean Hyperglycemic Hormone (CHH)-family Neuropeptides. Molecular & Cellular Proteomics. 2012;11:1951-1964.
Hui LM, Xiang F, Zhang YZ, Li LJ. Mass spectrometric elucidation of the neuropeptidome of a crustacean neuroendocrine organ. Peptides. 2012;36:230-239.
Cunningham R, Wang JX, Wellner D, Li LJ. Investigation and reduction of sub-microgram peptide loss using molecular weight cut-off fractionation prior to mass spectrometric analysis. Journal of Mass Spectrometry. 2012;47:1327-1332.
Ye H, Greer T, Li LJ. Probing neuropeptide signaling at the organ and cellular domains via imaging mass spectrometry. Journal of Proteomics. 2012;75:5014-5026.
Sturm R, Sheynkman G, Booth C, Smith LM, Pedersen JA, Li LJ. Absolute Quantification of Prion Protein (90-231) Using Stable Isotope-Labeled Chymotryptic Peptide Standards in a LC-MRM AQUA Workflow. Journal of the American Society for Mass Spectrometry. 2012;23:1522-1533.
Zhang Z, Wang J, Hui L, Li LJ. Membrane-assisted capillary isoelectric focusing coupling with matrix-assisted laser desorption/ionization-Fourier transform mass spectrometry for neuropeptide analysis. Journal of Chromatography A. 2011;1218:5336-5343.
Ye H, Greer T, Li LJ. From pixel to voxel: a deeper view of biological tissue by 3D mass spectral imaging. Bioanalysis. 2011;3:313-332.
Wei X, Herbst A, Ma D, Aiken J, Li LJ. A Quantitative Proteomic Approach to Prion Disease Biomarker Research: Delving into the Glycoproteome. Journal of Proteome Research. 2011;10:2687-2702.
Wang J, Ye H, Zhang Z, Xiang F, Girdaukas G, Li LJ. Advancing Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometric Imaging for Capillary Electrophoresis Analysis of Peptides. Analytical Chemistry. 2011;83:3462-3469.
Szabo TM, Chen R, Goeritz ML, Maloney RT, Tang LS, Li LJ, et al.. Distribution and Physiological Effects of B-Type Allatostatins (Myoinhibitory Peptides, MIPs) in the Stomatogastric Nervous System of the Crab Cancer borealis. Journal of Comparative Neurology. 2011;519:2658-2676.
Hui L, Cunningham R, Zhang Z, Cao W, Jia C, Li LJ. Discovery and Characterization of the Crustacean Hyperglycemic Hormone Precursor Related Peptides (CPRP) and Orcokinin Neuropeptides in the Sinus Glands of the Blue Crab Callinectes sapidus Using Multiple Tandem Mass Spectrometry Techniques. Journal of Proteome Research. 2011;10:4219-4229.
Zhang J, Lanham KA, Peterson RE, Heideman W, Li LJ. Characterization of the adult zebrafish cardiac proteome using online pH gradient strong cation exchange-RP 2D LC coupled with ESI MS/MS. Journal of Separation Science. 2010;33:1462-1471.
Xiang F, Ye H, Chen R, Fu Q, Li LJ. N,N-Dimethyl Leucines as Novel Isobaric Tandem Mass Tags for Quantitative Proteomics and Peptidomics. Analytical Chemistry. 2010;82:2817-2825.
Wei X, Dulberger C, Li LJ. Characterization of Murine Brain Membrane Glycoproteins by Detergent Assisted Lectin Affinity Chromatography. Analytical Chemistry. 2010;82:6329-6333.
Wang J, Zhang Y, Xiang F, Zhang Z, Li LJ. Combining capillary electrophoresis matrix-assisted laser desorption/ionization mass spectrometry and stable isotopic labeling techniques for comparative crustacean peptidomics. Journal of Chromatography A. 2010;1217:4463-4470.
Ma M, Gard AL, Xiang F, Wang J, Davoodian N, Lenz PH, et al.. Combining in silico transcriptome mining and biological mass spectrometry for neuropeptide discovery in the Pacific white shrimp Litopenaeus vannamei. Peptides. 2010;31:27-43.
Herbst A, Wei X, Ma D, Li LJ, Aiken J. Quantitative Proteomic Analysis of Prion Infected Mouse Plasma. Prion. 2010;4:218-218.
Chen R, Li LJ. Mass spectral imaging and profiling of neuropeptides at the organ and cellular domains. Analytical and Bioanalytical Chemistry. 2010;397:3185-3193.
Chen R, Jiang X, Conaway MCPrieto, Mohtashemi I, Hui L, Viner R, et al.. Mass Spectral Analysis of Neuropeptide Expression and Distribution in the Nervous System of the Lobster Homarus americanus. Journal of Proteome Research. 2010;9:818-832.
Chen R, Hui L, Cape SS, Wang J, Li LJ. Comparative Neuropeptidomic Analysis of Food Intake via a Multifaceted Mass Spectrometric Approach. ACS Chemical Neuroscience. 2010;1:204-214.
Thomas-Virnig CL, Centanni JM, Johnston CE, He LK, Schlosser SJ, Van Winkle KF, et al.. Inhibition of Multidrug-resistant Acinetobacter baumannii by Nonviral Expression of hCAP-18 in a Bioengineered Human Skin Tissue. Molecular Therapy. 2009;17:562-569.
Ma MM, Szabo TM, Jia CX, Marder E, Li LJ. Mass spectrometric characterization and physiological actions of novel crustacean C-type allatostatins. Peptides. 2009;30:1660-1668.
Ma MM, Chen RB, Ge Y, He H, Marshall AG, Li LJ. Combining Bottom-Up and Top-Down Mass Spectrometric Strategies for De Novo Sequencing of the Crustacean Hyperglycemic Hormone from Cancer borealis. Analytical Chemistry. 2009;81:240-247.
Ma MM, Bors EK, Dickinson ES, Kwiatkowski MA, Sousa GL, Henry RP, et al.. Characterization of the Carcinus maenas neuropeptidome by mass spectrometry and functional genomics. General and Comparative Endocrinology. 2009;161:320-334.
Ma M, Sturm RM, Kutz-Naber KK, Fu Q, Li LJ. Immunoaffinity-based mass spectrometric characterization of the FMRFamide-related peptide family in the pericardial organ of Cancer borealis. Biochemical and Biophysical Research Communications. 2009;390:325-330.
Dowell JA, Johnson JA, Li LJ. Identification of Astrocyte Secreted Proteins with a Combination of Shotgun Proteomics and Bioinformatics. Journal of Proteome Research. 2009;8:4135-4143.
Cho YK, Chen I, Wei X, Li LJ, Shusta EV. A yeast display immunoprecipitation method for efficient isolation and characterization of antigens. Journal of Immunological Methods. 2009;341:117-126.
Chen RB, Hui LM, Sturm RM, Li LJ. Three Dimensional Mapping of Neuropeptides and Lipids in Crustacean Brain by Mass Spectral Imaging. Journal of the American Society for Mass Spectrometry. 2009;20:1068-1077.
Schmidt JJ, McLlwain S, Page D, Christie AE, Li LJ. Combining MALDI-FTMS and bioinformatics for rapid peptidomic comparisons. Journal of Proteome Research. 2008;7:887-896.
Ma M, Chen R, Sousa GL, Bors EK, Kwiatkowski MA, Goiney CC, et al.. Mass spectral characterization of peptide transmitters/hormones in the nervous system and neuroendocrine organs of the American lobster Homarus americanus. General and Comparative Endocrinology. 2008;156:395-409.
Christie AE, Cashman CR, Brennan HR, Ma M, Sousa GL, Li LJ, et al.. Identification of putative crustacean neuropeptides using in silico analyses of publicly accessible expressed sequence tags. General and Comparative Endocrinology. 2008;156:246-264.
Zhao L, Shi X, Li LJ, Miller DJ. Dynamin 2 associates with complexins and is found in the acrosomal region of mammalian sperm. Molecular Reproduction and Development. 2007;74:750-757.
Saideman SR, Ma M, Kutz-Naber KK, Cook A, Torfs P, Schoofs L, et al.. Modulation of rhythmic motor activity by pyrokinin peptides. Journal of Neurophysiology. 2007;97:579-595.
Dickinson PS, Stevens JS, Rus S, Brennan HR, Goiney CC, Smith CM, et al.. Identification and cardiotropic actions of sulfakinin peptides in the American lobster Homarus americanus. Journal of Experimental Biology. 2007;210:2278-2289.
DeKeyser SS, Kutz-Naber KK, Schmidt JJ, Barrett-Wilt GA, Li LJ. Imaging mass spectrometry of neuropeptides in decapod crustacean neuronal tissues. Journal of Proteome Research. 2007;6:1782-1791.
Fu Q, Li LJ. Neutral loss of water from the b ions with histidine at the C-terminus and formation of the c ions involving lysine side chains. Journal of Mass Spectrometry. 2006;41:1600-1607.
Fu Q, Li LJ. Investigation of several unique tandem mass spectrometric fragmentation patterns of NFDEIDR, an orcokinin analog, and its N-terminal dimethylated form. Rapid Communications in Mass Spectrometry. 2006;20:553-562.
Yew JY, Kutz KK, Dikler S, Messinger L, Li LJ, Stretton AO. Mass spectrometric map of neuropeptide expression in Ascaris suum. Journal of Comparative Neurology. 2005;488:396-413.
Proekt A, Vilim FS, Alexeeva V, Brezina V, Friedman A, Jing J, et al.. Identification of a new neuropeptide precursor reveals a novel source of extrinsic modulation in the feeding system of Aplysia. Journal of Neuroscience. 2005;25:9637-9648.
Messinger DI, Kutz KK, Le T, Verley DR, Hsu YWA, Ngo CT, et al.. Identification and characterization of a tachykinin-containing neuroendocrine organ in the commissural ganglion of the crab Cancer productus. Journal of Experimental Biology. 2005;208:3303-3319.
Fu Q, Li LJ. De novo sequencing of neuropeptides using reductive isotopic methylation and investigation of ESI QTOF MS/MS fragmentation pattern of neuropeptides with N-terminal dimethylation. Analytical Chemistry. 2005;77:7783-7795.
Fu Q, Kutz KK, Schmidt JJ, Hsu YWA, Messinger DI, Cain SD, et al.. Hormone complement of the Cancer productus sinus gland and pericardial organ: An anatomical and mass spectrometric investigation [Review]. Journal of Comparative Neurology. 2005;493:607-626.
Fu Q, Goy MF, Li LJ. Identification of neuropeptides from the decapod crustacean sinus glands using nanoscale liquid chromatography tandem mass spectrometry. Biochemical and Biophysical Research Communications. 2005;337:765-778.
Fu Q, Christie AE, Li LJ. Mass spectrometric characterization of crustacean hyperglycemic hormone precursor-related peptides (CPRPs) from the sinus gland of the crab, Cancer productus. Peptides. 2005;26:2137-2150.
Kutz KK, Schmidt JJ, Li LJ. In situ tissue analysis of neuropeptides by MALDI FTMS in-cell accumulation. Analytical Chemistry. 2004;76:5630-5640.
Li LJ, Kelley WP, Billimoria CP, Christie AE, Pulver SR, Sweedler JV, et al.. Mass spectrometric investigation of the neuropeptide complement and release in the pericardial organs of the crab, Cancer borealis. Journal of Neurochemistry. 2003;87:642-656.
Hummon AB, Hummon NP, Corbin RW, Li LJ, Vilim FS, Weiss KR, et al.. From precursor to final peptides: A statistical sequence-based approach to predicting prohormone processing. Journal of Proteome Research. 2003;2:650-656.
Masselon C, Pasa-Tolic L, Li LJ, Anderson GA, Harkewicz R, Smith RD. Identification of tryptic peptides from large databases using multiplexed tandem mass spectrometry: simulations and experimental results. Proteomics. 2003;3:1279-1286.
Li LJ, Sweedler JV. Measuring neuropeptides with single-cell MALDI-MS. In: Silberring J, Ekman R. Mass Spectrometry And Hyphenated Techniques In Neuropeptide Research. New York: Wiley and Sons, Inc.; 2002. pp. 495-517.
Li LJ, Pulver SR, Kelley WP, Thirumalai V, Sweedler JV, Marder E. Orcokinin peptides in developing and adult crustacean stomatogastric nervous systems and pericardial organs. Journal of Comparative Neurology. 2002;444:227-244.
Sweedler JV, Li LJ, Floyd P, Gilly W. Mass spectrometric survey of peptides in cephalopods with an emphasis on the FMRFamide-related peptides. Journal of Experimental Biology. 2000;203:3565-3573.
Li LJ, Romanova EV, Rubakhin SS, Alexeeva V, Weiss KR, Vilim FS, et al.. Peptide profiling of cells with multiple gene products: Combining immunochemistry and MALDI mass spectrometry with on-plate microextraction. Analytical Chemistry. 2000;72:3867-3874.
Li LJ, Garden RW, Sweedler JV. Single-cell MALDI: a new tool for direct peptide profiling. Trends in Biotechnology. 2000;18:151-160.
Rubakhin SS, Li LJ, Moroz TP, Sweedler JV. Characterization of the Aplysia californica cerebral ganglion F cluster. Journal of Neurophysiology. 1999;81:1251-1260.
Li LJ, Garden RW, Romanova EV, Sweedler JV. In situ sequencing of peptides from biological tissues and single cells using MALDI-PSD/CID analysis. Analytical Chemistry. 1999;71:5451-5458.
Li LJ, Garden RW, Floyd PD, Moroz TP, Gleeson JM, Sweedler JV, et al.. Egg-laying hormone peptides in the Aplysiidae family. Journal of Experimental Biology. 1999;202:2961-2973.
Garden RW, Moroz TP, Gleeson JM, Floyd PD, Li LJ, Rubakhin SS, et al.. Formation of N-pyroglutamyl peptides from N-Glu and N-Gln precursors in Aplysia neurons. Journal of Neurochemistry. 1999;72:676-681.
Floyd PD, Li LJ, Rubakhin SS, Sweedler JV, Horn CC, Kupfermann I, et al.. Insulin prohormone processing, distribution, and relation to metabolism in Aplysia californica. Journal of Neuroscience. 1999;19:7732-7741.
Floyd PD, Li LJ, Moroz TP, Sweedler JV. Characterization of peptides from Aplysia using microbore liquid chromatography with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry guided purification. Journal of Chromatography A. 1999;830:105-113.
Li LJ, Moroz TP, Garden RW, Floyd PD, Weiss KR, Sweedler JV. Mass spectrometric survey of interganglionically transported peptides in Aplysia. Peptides. 1998;19:1425-1433.
Garden RW, Shippy SA, Li LJ, Moroz TP, Sweedler JV. Proteolytic processing of the Aplysia egg-laying hormone prohormone. Proceedings of the National Academy of Sciences of the United States of America. 1998;95:3972-3977.
Schecter A, Li LJ. Dioxins, dibenzofurans, dioxin-like PCBs, and DDE in U.S. fast food, 1995. Chemosphere. 1997;34:1449-1457.
Jiang K, Li LJ, Chen Y, Jin J. Determination of PCDD/Fs and dioxin-like PCBs in Chinese commercial PCBs and emissions from a testing PCB incinerator. Chemosphere. 1997;34:941-950.
Schecter A, Paepke O, Lis A, Ball M, Rayan JJ, Olson JR, et al.. Decrease in milk and blood dioxin levels over two years in a mother nursing twins: estimates of decreased maternal and increased infant dioxin body burden from nursing. Chemosphere. 1996;32:543-9.
Jiang K, Li LJ, Chen Y. Dioxins in stack ash from PCB waste incinerator. Huanjing Kexue. 1996;17:68-71.
Schecter A, Li LJ, Olson JR. Dioxins in U.S. fast food. Organohalogen Compd. 1995;26:135-9.
Li LJ, Jiang K. Determination of toxic equivalents of PCDD/Fs in two Chinese commercial PCBs by 13C isotope dilution method. Huanjing Kexue Xuebao. 1995;15:433-9.
Li LJ, Jiang K. Determination of dioxin-like PCB (halocarbon) in both commercially available PCBs in China and stack ash from PCB incinerator. Huanjing Kexue. 1995;16:55-8.
Li LJ, Chen Y, Zhou Y, Wu J, Jiang K. Use of acid-base silica/alumina column and gas chromatography-mass spectrometry (GC/MS) methods for determination of residual PCBs in the solid wastes of an incinerator. Huanjing Huaxue. 1995;14:322-8.
Jin J, Li LJ, Jiang K. Toxicity of dioxin-like compounds. Shanghai Huanjing Kexue. 1995;14:29-32, 42.
Jiang K, Li LJ, Chen Y, Li S, Gong Y. Residual dioxins in Chinese schistosomiasis region and its eco-environmental risk. Chinese Science Bulletin. 1995;40:1740-7.
Jiang K, Chen Y, Li LJ. PCDD/Fs in sodium pentachlorophenate (Na - PCP) and human blood, milk and sediment samples from Chinese schistosomiasis areas. J. Environ. Sci. (China). 1995;7:52-9.
Li LJ, Chen Y, Chiu C, Poole G, Miles W, Jiang K. PCDD/Fs in sediment samples from Chinese schistosomiasis areas and potential human health effects. Organohalogen Compd. 1994;20:155-8.
Li LJ, Wu J, Chen Y, Jiang K. Determination of polychlorinated biphenyls in transformer oils. Huanjing Kexue. 1993;14:69-72.