Publications

Renner LD, Zan JD, Hu LI, Martinez M, Resto PJ, Siegel AC, et al.. Detection of ESKAPE Bacterial Pathogens at the Point of Care Using Isothermal DNA-Based Assays in a Portable Degas-Actuated Microfluidic Diagnostic Assay Platform. Applied and Environmental Microbiology. 2017;83:13.
Hurley KA, Santos TMA, Fensterwald MR, Rajendran M, Moore JT, Balmond EI, et al.. Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase. Med. Chem. Commun. 2017;8:942-951.
Auer GK, Weibel DB. Bacterial Cell Mechanics. Biochemistry. 2017;56:3710-3724.
Wong F, Renner LD, Ozbaykal G, Paulose J, Weibel DB, van Teeffelen S, et al.. Mechanical strain sensing implicated in cell shape recovery in Escherichia coli. Nature Microbiology. 2017;2.
Mushenheim PC, Pendery JS, Weibel DB, Spagnolie SE, Abbott NL. Straining soft colloids in aqueous nematic liquid crystals. Proceedings of the National Academy of Sciences of the United States of America. 2016;113:5564-5569.
Lin TY, Weibel DB. Organization and function of anionic phospholipids in bacteria. Applied Microbiology and Biotechnology. 2016;100:4255-4267.
Hurley KA, Santos TMA, Nepomuceno GM, Huynh V, Shaw JT, Weibel DB. Targeting the Bacterial Division Protein FtsZ. Journal of Medicinal Chemistry. 2016;59:6975-6998.
Zhang LL, Rajendram M, Weibel DB, Yethiraj A, Cui Q. Ionic Hydrogen Bonds and Lipid Packing Defects Determine the Binding Orientation and Insertion Depth of RecA on Multicomponent Lipid Bilayers. Journal of Physical Chemistry B. 2016;120:8424-8437.
Dufour YS, Gillet S, Frankel NW, Weibel DB, Emonet T. Direct Correlation between Motile Behavior and Protein Abundance in Single Cells. Plos Computational Biology. 2016;12.
Auer GK, Lee TK, Rajendram M, Cesar S, Miguel A, Huang KC, et al.. Mechanical Genomics Identifies Diverse Modulators of Bacterial Cell Stiffness. Cell Systems. 2016;2:402-411.
Mushenheim PC, Trivedi RR, Roy SS, Arnold MS, Weibel DB, Abbott NL. Effects of confinement, surface-induced orientations and strain on dynamical behaviors of bacteria in thin liquid crystalline films. Soft Matter. 2015;11:6821-6831.
Lin TY, Santos TMA, Kontur WS, Donohue TJ, Weibel DB. A Cardiolipin-Deficient Mutant of Rhodobacter sphaeroides Has an Altered Cell Shape and Is Impaired in Biofilm Formation. Journal of Bacteriology. 2015;197:3446-3455.
Crooks JA, Stilwell MD, Oliver PM, Zhong Z, Weibel DB. Decoding the Chemical Language of Motile Bacteria by Using High-Throughput Microfluidic Assays. Chembiochem. 2015;16:2151-2155.
Trivedi RR, Maeda R, Abbott NL, Spagnolie SE, Weibel DB. Bacterial transport of colloids in liquid crystalline environments. Soft Matter. 2015;11:8404-8408.
Liljander A, Yu MY, O'Brien E, Heller M, Nepper JF, Weibel DB, et al.. Field-Applicable Recombinase Polymerase Amplification Assay for Rapid Detection of Mycoplasma capricolum subsp capripneumoniae. Journal of Clinical Microbiology. 2015;53:2810-2815.
Rajendram M, Zhang LL, Reynolds BJ, Auer GK, Tuson HH, Ngo KV, et al.. Anionic Phospholipids Stabilize RecA Filament Bundles in Escherichia coli. Molecular Cell. 2015;60:374-384.
Zhou MQ, Eun YJ, Guzei IA, Weibel DB. Structure-Activity Studies of Divin: An Inhibitor of Bacterial Cell Division. Acs Medicinal Chemistry Letters. 2013;4:880-885.
Tuson HH, Weibel DB. Bacteria-surface interactions. Soft Matter. 2013;9:4368-4380.
Tuson HH, Copeland MF, Carey S, Sacotte R, Weibel DB. Flagellum Density Regulates Proteus mirabilis Swarmer Cell Motility in Viscous Environments. Journal of Bacteriology. 2013;195:368-377.
Oliver PM, Crooks JA, Yoon EJ, Weibel DB. A Revised Model of Nonyl Acridine Orange Binding to Anionic Phospholipids. Biophysical Journal. 2013;104:373A-374A.
Jakiela S, S. Tomasz K, Cybulski O, Weibel DB, Garstecki P. Bacterial Growth and Adaptation in Microdroplet Chemostats. Angewandte Chemie-International Edition. 2013;.
Shkoporov AN, Efimov BA, Khokhlova EV, Chaplin AV, Kafarskaya LI, Durkin AS, et al.. Draft Genome Sequences of Two Pairs of Human Intestinal Bifidobacterium longum subsp. longum Strains, 44B and 1-6B and 35B and 2-2B, Consecutively Isolated from Two Children after a 5-Year Time Period. Genome announcements. 2013;1.
Foss MH, Eun YJ, Grove CI, Pauw DA, Sorto NA, Rensvold JW, et al.. Inhibitors of bacterial tubulin target bacterial membranes in vivo. Medchemcomm. 2013;4:112-119.
Eun Y-J, Zhou M, Kiekebusch D, Schlimpert S, Trivedi RR, Bakshi S, et al.. Divin: a small molecule inhibitor of bacterial divisome assembly. Journal of the American Chemical Society. 2013;135:9768-9776.
Tuson HH, Renner LD, Weibel DB. Polyacrylamide hydrogels as substrates for studying bacteria. Chemical Communications. 2012;48:1595-1597.
Tuson HH, Auer GK, Renner LD, Hasebe M, Tropini C, Salick M, et al.. Measuring the stiffness of bacterial cells from growth rates in hydrogels of tunable elasticity. Molecular Microbiology. 2012;84:874-891.
Renner LD, Weibel DB. MinD and MinE Interact with Anionic Phospholipids and Regulate Division Plane Formation in Escherichia coli. Journal of Biological Chemistry. 2012;287:38835-38844.
Kim MB, O'Brien TE, Moore JT, Anderson DE, Foss MH, Weibel DB, et al.. The Synthesis and Antimicrobial Activity of Heterocyclic Derivatives of Totarol. Acs Medicinal Chemistry Letters. 2012;3:818-822.
Hou S, Wieczorek SA, Kaminski TS, Ziebacz N, Tabaka M, Sorto NA, et al.. Characterization of Caulobacter crescentus FtsZ Protein Using Dynamic Light Scattering. Journal of Biological Chemistry. 2012;287:23878-23886.
Ho JY, Cira NJ, Crooks JA, Baeza J, Weibel DB. Rapid Identification of ESKAPE Bacterial Strains Using an Autonomous Microfluidic Device. Plos One. 2012;7.
Eun YJ, Foss MH, Kiekebusch D, Pauw DA, Westler WM, Thanbichler M, et al.. DCAP: A Broad-Spectrum Antibiotic That Targets the Cytoplasmic Membrane of Bacteria. Journal of the American Chemical Society. 2012;134:11322-11325.
Cira NJ, Ho JY, Dueck ME, Weibel DB. A self-loading microfluidic device for determining the minimum inhibitory concentration of antibiotics. Lab on a Chip. 2012;12:1052-1059.
Churski K, Kaminski TS, Jakiela S, Kamysz W, Baranska-Rybak W, Weibel DB, et al.. Rapid screening of antibiotic toxicity in an automated microdroplet system. Lab on a Chip. 2012;12:1629-1637.
Renner LD, Weibel DB. Physicochemical regulation of biofilm formation. Mrs Bulletin. 2011;36:347-355.
Renner LD, Weibel DB. Cardiolipin microdomains localize to negatively curved regions of Escherichia coli membranes. Proceedings of the National Academy of Sciences of the United States of America. 2011;108:6264-6269.
Renner LD, Weibel DB. The Role of Cardiolipin Domains in Protein Localization in Bacterial Cells. Biophysical Journal. 2011;100:526-526.
Foss MH, Hurley KA, Sorto NA, Lackner LL, Thornton KM, Shaw JT, et al.. N-Benzyl-3-sulfonamidopyrrolidines Are a New Class of Bacterial DNA Gyrase Inhibitors. Acs Medicinal Chemistry Letters. 2011;2:289-292.
Foss MH, Eun YJ, Weibel DB. Chemical-Biological Studies of Subcellular Organization in Bacteria. Biochemistry. 2011;50:7719-7734.
Flickinger ST, Copeland MF, Downes EM, Braasch AT, Tuson HH, Eun YJ, et al.. Quorum Sensing between Pseudomonas aeruginosa Biofilms Accelerates Cell Growth. Journal of the American Chemical Society. 2011;133:5966-5975.
Eun YJ, Utada AS, Copeland MF, Takeuchi S, Weibel DB. Encapsulating Bacteria in Agarose Microparticles Using Microfluidics for High-Throughput Cell Analysis and Isolation. ACS Chemical Biology. 2011;6:260-266.
Foss MH, Weibel DB. Oligochlorophens Are Potent Inhibitors of Bacillus anthracis. Antimicrobial Agents and Chemotherapy. 2010;54:3988-3990.
Copeland MF, Flickinger ST, Tuson HH, Weibel DB. Studying the Dynamics of Flagella in Multicellular Communities of Escherichia coli by Using Biarsenical Dyes. Applied and Environmental Microbiology. 2010;76:1241-1250.
Muralimohan A, Eun YJ, Bhattacharyya B, Weibel DB. Dissecting microbiological systems using materials science. Trends in Microbiology. 2009;17:100-108.
Garstecki P, Tierno P, Weibel DB, Sagues F, Whitesides GM. Propulsion of flexible polymer structures in a rotating magnetic field. Journal of Physics-Condensed Matter. 2009;21.
Eun YJ, Weibel DB. Fabrication of Microbial Biofilm Arrays by Geometric Control of Cell Adhesion. Langmuir. 2009;25:4643-4654.
Copeland MF, Weibel DB. Bacterial swarming: a model system for studying dynamic self-assembly. Soft Matter. 2009;5:1174-1187.
Cabeen MT, Charbon G, Vollmer W, Born P, Ausmees N, Weibel DB, et al.. Bacterial cell curvature through mechanical control of cell growth. EMBO Journal. 2009;28:1208-1219.
Bean GJ, Fllckinger ST, Westler WM, McCully ME, Sept D, Weibel DB, et al.. A22 Disrupts the Bacterial Actin Cytoskeleton by Directly Binding and Inducing a Low-Affinity State in MreB. Biochemistry. 2009;48:4852-4857.
Winkleman A, McCarty LS, Zhu T, Weibel DB, Suo ZG, Whitesides GM. Templated self-assembly over patterned electrodes by an applied electric field: Geometric constraints and diversity of materials. Journal of Microelectromechanical Systems. 2008;17:900-910.
Weibel DB. Building communities one bacterium at a time. Proceedings of the National Academy of Sciences of the United States of America. 2008;105:18075-18076.
Krishnamurthy VM, Kaufman GK, Urbach AR, Gitlin I, Gudiksen KL, Weibel DB, et al.. Carbonic anhydrase as a model for biophysical and physical-organic studies of proteins and protein-ligand binding. Chemical Reviews. 2008;108:946-1051.
Weibel DB, Siegel AC, Lee A, George AH, Whitesides GM. Pumping fluids in microfluidic systems using the elastic deformation of poly(dimethylsiloxane). Lab on a Chip. 2007;7:1832-1836.
Weibel DB, DiLuzio WR, Whitesides GM. Microfabrication meets microbiology. Nature Reviews Microbiology. 2007;5:209-218.
Siegel AC, Bruzewicz DA, Weibel DB, Whitesides GM. Microsolidics: Fabrication of three-dimensional metallic microstructures in poly(dimethylsiloxane). Advanced Materials. 2007;19:727-+.
Garner EC, Campbell CS, Weibel DB, Mullins RD. Reconstitution of DNA segregation driven by assembly of a prokaryotic actin homolog. Science. 2007;315:1270-1274.
Weibel DB, Whitesides GM. Applications of microfluidics in chemical biology. Current Opinion in Chemical Biology. 2006;10:584-591.
Siegel AC, Shevkoplyas SS, Weibel DB, Bruzewicz DA, Martinez AW, Whitesides GM. Cofabrication of electromagnets and microfluldic systems in poly(dimethylsiloxane). Angewandte Chemie-International Edition. 2006;45:6877-6882.
Schroeder FC, del Campo ML, Grant JB, Weibel DB, Smedley SR, Bolton KL, et al.. Pinoresinol: A lignol of plant origin serving for defense in a caterpillar. Proceedings of the National Academy of Sciences of the United States of America. 2006;103:15497-15501.
Xu SQ, Nie ZH, Seo M, Lewis P, Kumacheva E, Stone HA, et al.. Generation of monodisperse particles by using microfluidics: Control over size, shape, and composition. Angewandte Chemie-International Edition. 2005;44:724-728.
Weibel DB, Lee A, Mayer M, Brady SF, Bruzewicz D, Yang J, et al.. Bacterial printing press that regenerates its ink: Contact-printing bacteria using hydrogel stamps. Langmuir. 2005;21:6436-6442.
Weibel DB, Kruithof M, Potenta S, Sia SK, Lee A, Whitesides GM. Torque-actuated valves for microfluidics. Analytical Chemistry. 2005;77:4726-4733.
Weibel DB, Garstecki P, Whitesides GM. Combining microscience and neurobiology. Current Opinion in Neurobiology. 2005;15:560-567.
Weibel DB, Garstecki P, Ryan D, DiLuzio WR, Mayer M, Seto JE, et al.. Microoxen: Microorganisms to move microscale loads. Proceedings of the National Academy of Sciences of the United States of America. 2005;102:11963-11967.
Weibel DB, Boulatov R, Lee A, Ferrigno R, Whitesides GM. Modeling the anodic half-cell of a low-temperature coal fuel cell. Angewandte Chemie-International Edition. 2005;44:5682-5686.
Takeuchi S, Garstecki P, Weibel DB, Whitesides GM. An axisymmetric flow-focusing microfluidic device. Advanced Materials. 2005;17:1067-+.
Takeuchi S, DiLuzio WR, Weibel DB, Whitesides GM. Controlling the shape of filamentous cells of Escherichia coli. Nano Letters. 2005;5:1819-1823.
Stevens MM, Mayer M, Anderson DG, Weibel DB, Whitesides GM, Langer R. Direct patterning of mammalian cells onto porous tissue engineering substrates using agarose stamps. Biomaterials. 2005;26:7636-7641.
DiLuzio WR, Turner L, Mayer M, Garstecki P, Weibel DB, Berg HC, et al.. Escherichia coli swim on the right-hand side. Nature. 2005;435:1271-1274.
Schroeder FC, Weibel DB, Meinwald J. Chiral silylation reagents: Determining configuration via NMR-spectroscopic coanalysis. Organic Letters. 2004;6:3019-3022.
Williamson RT, Sosa ACB, Mitra A, Seaton PJ, Weibel DB, Schroeder FC, et al.. New silyl ether reagents for the absolute stereochemical determination of secondary alcohols. Organic Letters. 2003;5:1745-1748.
Weibel DB, Shevy LE, Schroeder FC, Meinwald J. Synthesis of mayolene-16 and mayolene-18: Larval defensive lipids from the European cabbage butterfly. Journal of Organic Chemistry. 2002;67:5896-5900.
Smedley SR, Schroeder FC, Weibel DB, Meinwald J, Lafleur KA, Renwick JA, et al.. Mayolenes: Labile defensive lipids from the glandular hairs of a caterpillar (Pieris rapae). Proceedings of the National Academy of Sciences of the United States of America. 2002;99:6822-6827.
Weibel DB, Oldham NJ, Feld B, Glombitza G, Dettner K, Boland W. Iridoid biosynthesis in staphylinid rove beetles (Coleoptera : Staphylinidae, Philonthinae). Insect Biochemistry and Molecular Biology. 2001;31:583-591.
Weibel DB, Walker TR, Schroeder FC, Meinwald J. Chiral silylation reagents for the determination of absolute configuration by NMR spectroscopy. Organic Letters. 2000;2:2381-2383.
Weibel DB, Attygalle AB, Shevy LE, Meinwald J. Cycloalkene budding: mass spectrometric studies of competitive and dual cycloalkene extrusion reactions from doubly unsaturated aldehyde N,N-dimethylhydrazones. Rapid Communications in Mass Spectrometry. 2000;14:1105-1109.
Weibel DB. Oxidodiperoxymolybdenum(pyridine) (hexamethylphorphoric triamide). Synlett. 2000;:1076-1076.
Weibel DB, Gevorgyan V, Yamamoto Y. Synthesis of polyether exomethylene paracyclophanes via an intramolecular Pd-catalyzed bis-enyne benzannulation protocol. Journal of Organic Chemistry. 1998;63:1217-1220.
Weibel DB, Yamamoto Y. Ruthenium-catalyzed cyclization of dienylalkynes via vinylidene intermediates: scope and limitations. Chemtracts. 1997;10:1034-1038.