|
Buchanan EG, James WH, Choi SH, Guo L, Gellman SH, Muller CW, et al. Single-conformation infrared spectra of model peptides in the amide I and amide II regions: Experiment-based determination of local mode frequencies and inter-mode coupling. Journal of Chemical Physics. 2012;137. |
|
Chae PS, Rasmussen SGF, Rana RR, Gotfryd K, Kruse AC, Manglik A, et al. A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane ProteinsMMINS P, 1994, BIOPHYSICAL CHEMISTRY, V53, P27. Chemistry-A European Journal. 2012;18:9485-9490. |
|
Guo L, Zhang WC, Guzei IA, Spencer LC, Gellman SH. New Preorganized gamma-Amino Acids as Foldamer Building Blocks. Organic Letters. 2012;14:2582-2585. |
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Guo L, Zhang WC, Guzei IA, Spencer LC, Gellman SH. Helical secondary structures in 2:1 and 1:2 alpha/gamma-peptide foldamers. Tetrahedron. 2012;68:4413-4417. |
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Haase HS, Peterson-Kaufman KJ, Levengood SKL, Checco JW, Murphy WL, Gellman SH. Extending Foldamer Design beyond alpha-Helix Mimicry: alpha/beta-Peptide Inhibitors of Vascular Endothelial Growth Factor Signaling. Journal of the American Chemical Society. 2012;134:7652-7655. |
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Liu RH, Masters KS, Gellman SH. Polymer Chain Length Effects on Fibroblast Attachment on Nylon-3-Modified Surfaces. Biomacromolecules. 2012;13:1100-1105. |
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Mortenson DE, Satyshur KA, Guzei IA, Forest KT, Gellman SH. Quasiracemic Crystallization as a Tool To Assess the Accommodation of Noncanonical Residues in Nativelike Protein Conformations. Journal of the American Chemical Society. 2012;134:2473-2476. |
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Zhang JH, Markiewicz MJ, Weisblum B, Stahl SS, Gellman SH. Functionally Diverse Nylon-3 Copolymers from Readily Accessible beta-Lactams. Acs Macro Letters. 2012;1:714-717. |
|
Johnson LM, Mortenson DE, Yun HG, Horne WS, Ketas TJ, Lu M, et al. Enhancement of alpha-Helix Mimicry by an alpha/beta-Peptide Foldamer via Incorporation of a Dense Ionic Side-Chain Array. Journal of the American Chemical Society. 2012;134:7317-7320. |
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Liu RH, Vang KZ, Kreeger PK, Gellman SH, Masters KS. Experimental and computational analysis of cellular interactions with nylon-3-bearing substrates. Journal of Biomedical Materials Research Part A. 2012;100A:2750-2759. |
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Steinkruger JD, Bartlett GJ, Hadley EB, Fay L, Woolfson DN, Gellman SH. The d '-d-d ' Vertical Triad Is Less Discriminating Than the a '-a-a ' Vertical Triad in the Antiparallel Coiled-Coil Dimer Motif. Journal of the American Chemical Society. 2012;134:2626-2633. |
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Zhang J, Markiewicz MJ, Mowery BP, Weisblurn B, Stahl SS, Gellman SH. C-Terminal Functionalization of Nylon-3 Polymers: Effects of C-Terminal Groups on Antibacterial and Hemolytic Activities. Biomacromolecules. 2012;13:323-331. |
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Boersma MD, Haase HS, Peterson-Kaufman KJ, Lee EF, Clarke OB, Colman PM, et al. Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain. J Am Chem Soc. 2012;134(1):315-23. |
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Almeida AM, Li R, Gellman SH. Parallel β-sheet secondary structure is stabilized and terminated by interstrand disulfide cross-linking. J Am Chem Soc. 2012;134(1):75-8. |
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Steinkruger JD, Bartlett GJ, Woolfson DN, Gellman SH. Strong contributions from vertical triads to helix-partner preferences in parallel coiled coils. J Am Chem Soc. 2012;134(38):15652-5. |
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Woys AM, Almeida AM, Wang L, Chiu C-C, McGovern M, De Pablo JJ, et al. Parallel β-Sheet Vibrational Couplings Revealed by 2D IR Spectroscopy of an Isotopically Labeled Macrocycle: Quantitative Benchmark for the Interpretation of Amyloid and Protein Infrared Spectra. J Am Chem Soc. 2012;134(46):19118-28. |
|
Chae PS, Rana RR, Gotfryd K, Rasmussen SGF, Kruse AC, Cho KH, et al. Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study. Chem Commun (Camb). 2012; |
|
Acevedo-Velez C, Andre G, Dufrene YF, Gellman SH, Abbott NL. Single-Molecule Force Spectroscopy of beta-Peptides That Display Well-Defined Three-Dimensional Chemical Patterns. Journal of the American Chemical Society. 2011;133:3981-3988. |
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Buchanan EG, James, William H. III, Gutberlet A, Dean JC, Guo L, Gellman SH, et al. Single-conformation spectroscopy and population analysis of model gamma-peptides: New tests of amide stacking. Faraday Discussions. 2011;150:209-226. |
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Freire F, Almeida AM, Fisk JD, Steinkruger JD, Gellman SH. Impact of Strand Length on the Stability of Parallel-beta-Sheet Secondary Structure. Angewandte Chemie-International Edition. 2011;50:8735-8738. |
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Guo L, Zhang W, Reidenbach AG, Giuliano MW, Guzei IA, Spencer LC, et al. Characteristic Structural Parameters for the gamma-Peptide 14-Helix: Importance of Subunit Preorganization. Angewandte Chemie-International Edition. 2011;50:5843-5846. |
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Johnson LM, Horne SW, Gellman SH. Broad Distribution of Energetically Important Contacts across an Extended Protein Interface. Journal of the American Chemical Society. 2011;133:10038-10041. |
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Lee EF, Smith BJ, Horne SW, Mayer KN, Evangelista M, Colman PM, et al. Structural Basis of Bcl-x(L) Recognition by a BH3-Mimetic alpha/beta-Peptide Generated by Sequence-Based Design. Chembiochem. 2011;12:2025-2032. |
|
Pomerantz WC, Yuwono VM, Drake R, Hartgerink JD, Abbott NL, Gellman SH. Lyotropic Liquid Crystals Formed from ACHC-Rich beta-Peptides. Journal of the American Chemical Society. 2011;133:13604-13613. |
|
Rasmussen SGF, Choi H-J, Fung JJ, Pardon E, Casarosa P, Chae PS, et al. Structure of a nanobody-stabilized active state of the beta(2) adrenoceptor. Nature. 2011;469:175-U59. |
|
Rasmussen SGF, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, et al. Crystal structure of the beta(2) adrenergic receptor-Gs protein complex. Nature. 2011;477:549-U311. |
|
Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, et al. Structure and function of an irreversible agonist-beta(2) adrenoceptor complex. Nature. 2011;469:236-U129. |
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Sawada T, Gellman SH. Structural Mimicry of the alpha-Helix in Aqueous Solution with an Isoatomic alpha/beta/gamma-Peptide Backbone. Journal of the American Chemical Society. 2011;133:7336-7339. |
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Selao TT, Branca R, Chae PS, Lehtio J, Gellman SH, Rasmussen SGF, et al. Identification of Chromatophore Membrane Protein Complexes Formed under Different Nitrogen Availability Conditions in Rhodospirillum rubrum. Journal of Proteome Research. 2011;10:2703-2714. |
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Thiele CM, Pomerantz WC, Abbott NL, Gellman SH. Lyotropic liquid crystalline phases from helical β-peptides as alignment media. Chem Commun (Camb). 2011;47(1):502-4. |
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James WH, Buchanan EG, Guo L, Gellman SH, Zwier TS. Competition between amide stacking and intramolecular H bonds in γ-peptide derivatives: controlling nearest-neighbor preferences. J Phys Chem A. 2011;115(43):11960-70. |
|
James WH, Buchanan EG, Müller CW, Dean JC, Kosenkov D, Slipchenko LV, et al. Evolution of amide stacking in larger γ-peptides: triamide H-bonded cycles. J Phys Chem A. 2011;115(47):13783-98. |
|
Segman-Magidovich S, Lee M-R, Vaiser V, Struth B, Gellman SH, Rapaport H. Sheet-like assemblies of charged amphiphilic α/β-peptides at the air-water interface. Chemistry. 2011;17(52):14857-66. |
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Chae PS, Gotfryd K, Pacyna J, Miercke LJW, Rasmussen SGF, Robbins RA, et al. Tandem Facial Amphiphiles for Membrane Protein Stabilization. Journal of the American Chemical Society. 2010;132:16750-16752. |
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Chae PS, Guzei IA, Gellman SH. Crystallographic Characterization of N-Oxide Tripod Amphiphiles. Journal of the American Chemical Society. 2010;132:1953-1959. |
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Chae PS, Laible PD, Gellman SH. Tripod amphiphiles for membrane protein manipulation. Molecular Biosystems. 2010;6:89-94. |
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Chae PS, Rasmussen SGF, Rana RR, Gotfryd K, Chandra R, Goren MA, et al. Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins. Nature Methods. 2010;7:1003-U90. |
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Choi SH, Guzei IA, Spencer LC, Gellman SH. Crystallographic Characterization of 12-Helical Secondary Structure in beta-Peptides Containing Side Chain Groups. Journal of the American Chemical Society. 2010;132:13879-13885. |
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Dohm MT, Mowery BP, Czyzewski AM, Stahl SS, Gellman SH, Barron AE. Biophysical Mimicry of Lung Surfactant Protein B by Random Nylon-3 Copolymers. Journal of the American Chemical Society. 2010;132:7957-7967. |
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Guo L, Almeida AM, Zhang W, Reidenbach AG, Choi SH, Guzei IA, et al. Helix Formation in Preorganized beta/gamma-Peptide Foldamers: Hydrogen-Bond Analogy to the alpha-Helix without alpha-Amino Acid Residues. Journal of the American Chemical Society. 2010;132:7868-+. |
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James WH, Baquero EE, Choi SH, Gellman SH, Zwier TS. Laser Spectroscopy of Conformationally Constrained alpha/beta-Peptides: Ac-ACPC-Phe-NHMe and Ac-Phe-ACPC-NHMe. Journal of Physical Chemistry A. 2010;114:1581-1591. |
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Karlsson AJ, Flessner RM, Gellman SH, Lynn DM, Palecek SP. Polyelectrolyte Multilayers Fabricated from Antifungal beta-Peptides: Design of Surfaces that Exhibit Antifungal Activity Against Candida albicans. Biomacromolecules. 2010;11:2321-2328. |
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Price JL, Hadley EB, Steinkruger JD, Gellman SH. Detection and Analysis of Chimeric Tertiary Structures by Backbone Thioester Exchange: Packing of an alpha Helix against an alpha/beta-Peptide Helix. Angewandte Chemie-International Edition. 2010;49:366-369. |
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Price JL, Horne SW, Gellman SH. Structural Consequences of beta-Amino Acid Preorganization in a Self-Assembling alpha/beta-Peptide: Fundamental Studies of Foldameric Helix Bundles. Journal of the American Chemical Society. 2010;132:12378-12387. |
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Segman S, Lee M-R, Vaiser V, Gellman SH, Rapaport H. Highly Stable Pleated-Sheet Secondary Structure in Assemblies of Amphiphilic alpha/beta-Peptides at the Air-Water Interface. Angewandte Chemie-International Edition. 2010;49:716-719. |
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Steinkruger JD, Woolfson DN, Gellman SH. Side-Chain Pairing Preferences in the Parallel Coiled-Coil Dimer Motif: Insight on Ion Pairing between Core and Flanking Sites. Journal of the American Chemical Society. 2010;132:7586-+. |
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Thiele CM, Pomerantz WC, Abbott NL, Gellman SH. Lyotropic liquid crystalline phases from helical beta-peptides as alignment media. Chemical Communications. 2010;47:502-504. |
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Zhang J, Gellman SH, Stahl SS. Kinetics of Anionic Ring-Opening Polymerization of Variously Substituted beta-Lactams: Homopolymerization and Copolymerization. Macromolecules. 2010;43:5618-5626. |
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Choi SH, Guzei IA, Spencer LC, Gellman SH. Crystallographic Characterization of Helical Secondary Structures in 2:1 and 1:2 alpha/beta-Peptides. Journal of the American Chemical Society. 2009;131:2917-2924. |
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Freire F, Gellman SH. Macrocyclic Design Strategies for Small, Stable Parallel beta-Sheet Scaffolds. Journal of the American Chemical Society. 2009;131:7970-+. |
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Giuliano MW, Horne WS, Gellman SH. An alpha/beta-Peptide Helix Bundle with a Pure beta(3)-Amino Acid Core and a Distinctive Quaternary Structure. Journal of the American Chemical Society. 2009;131:9860-+. |
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Guo L, Chi Y, Almeida AM, Guzei IA, Parker BK, Gellman SH. Stereospecific Synthesis of Conformationally Constrained gamma-Amino Acids: New Foldamer Building Blocks That Support Helical Secondary Structure. Journal of the American Chemical Society. 2009;131:16018-+. |
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Horne WS, Johnson LM, Ketas TJ, Klasse PJ, Lu M, Moore JP, et al. Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers. Proceedings of the National Academy of Sciences of the United States of America. 2009;106:14751-14756. |
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James WH, Baquero EE, Shubert VA, Choi SH, Gellman SH, Zwier TS. Single-Conformation and Diastereomer Specific Ultraviolet and Infrared Spectroscopy of Model Synthetic Foldamers: alpha/beta-Peptides. Journal of the American Chemical Society. 2009;131:6574-6590. |
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James, William H. III, Mueller CW, Buchanan EG, Nix MGD, Guo L, Roskop L, et al. Intramolecular Amide Stacking and Its Competition with Hydrogen Bonding in a Small Foldamer. Journal of the American Chemical Society. 2009;131:14243-+. |
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James WH, Muller CW, Buchanan EG, Nix MGD, Guo L, Roskop L, et al. Intramolecular Amide Stacking and Its Competition with Hydrogen Bonding in a Small Foldamer. Journal of the American Chemical Society. 2009;131:14243-+. |
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Karlsson AJ, Pomerantz WC, Neilsen KJ, Gellman SH, Palecek SP. Effect of Sequence and Structural Properties on 14-Helical beta-Peptide Activity against Candida albicans Planktonic Cells and Biofilms. ACS Chemical Biology. 2009;4:567-579. |
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Lee EF, Sadowsky JD, Smith BJ, Czabotar PE, Peterson-Kaufman KJ, Colman PM, et al. High-Resolution Structural Characterization of a Helical alpha/beta-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-x(L). Angewandte Chemie-International Edition. 2009;48:4318-4322. |
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Lee M-R, Stahl SS, Gellman SH, Masters KS. Nylon-3 Copolymers that Generate Cell-Adhesive Surfaces Identified by Library Screening. Journal of the American Chemical Society. 2009;131:16779-16789. |
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Lu D, Windsor MA, Gellman SH, Keck JL. Peptide Inhibitors Identify Roles for SSB C-Terminal Residues in SSB/Exonuclease I Complex Formation. Biochemistry. 2009;48:6764-6771. |
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Miller CA, Gellman SH, Abbott NL, de Pablo JJ. Association of Helical beta-Peptides and their Aggregation Behavior from the Potential of Mean Force in Explicit Solvent. Biophysical Journal. 2009;96:4349-4362. |
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Mowery BP, Lindner AH, Weisblum B, Stahl SS, Gellman SH. Structure-activity Relationships among Random Nylon-3 Copolymers That Mimic Antibacterial Host-Defense Peptides. Journal of the American Chemical Society. 2009;131:9735-9745. |
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Muller MM, Windsor MA, Pomerantz WC, Gellman SH, Hilvert D. A Rationally Designed Aldolase Foldamer. Angewandte Chemie-International Edition. 2009;48:922-925. |
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Pomerantz WC, Hadley EB, Fry CG, Gellman SH. In Situ Monitoring of Backbone Thioester Exchange by F-19 NMR. Chembiochem. 2009;10:2177-2181. |
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Stephenson NA, Zhu J, Gellman SH, Stahl SS. Catalytic Transamidation Reactions Compatible with Tertiary Amide Metathesis under Ambient Conditions. Journal of the American Chemical Society. 2009;131:10003-10008. |
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Zhang JH, Kissounko DA, Lee SE, Gellman SH, Stahl SS. Access to Poly-beta-Peptides with Functionalized Side Chains and End Groups via Controlled Ring-Opening Polymerization of beta-Lactams. Journal of the American Chemical Society. 2009;131:1589-1597. |
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Freire F, Gellman SH. Macrocyclic design strategies for small, stable parallel beta-sheet scaffolds. J Am Chem Soc. 2009;131(23):7970-2. |
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Hoerter JM, Otte KM, Gellman SH, Cui Q, Stahl SS. Discovery and mechanistic study of Al-III-catalyzed transamidation of tertiary amides. Journal of the American Chemical Society. 2008;130:647-654. |
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Akkarawongsa R, Potocky TB, English EP, Gellman SH, Brandt CR. Inhibition of herpes simplex virus type 1 infection by cationic beta-peptides. Antimicrobial Agents and Chemotherapy. 2008;52:2120-2129. |
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Baquero EE, James, William H. III, Choi SH, Gellman SH, Zwier TS. Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta(3)-hPhe-NHMe and Ac-beta(3)-hTyr-NHMe. Journal of the American Chemical Society. 2008;130:4784-4794. |
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Baquero EE, James, William H. III, Choi SH, Gellman SH, Zwier TS. Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta(3)-hPhe-beta(3)-hAla-NHMe and Ac-beta(3)-hAla-beta(3)-hPhe-NHMe. Journal of the American Chemical Society. 2008;130:4795-4807. |
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Boersma MD, Sadowsky JD, Tomita YA, Gellman SH. Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein-protein recognition: Application to the Bim BH3 domain. Protein Science. 2008;17:1232-1240. |
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Chae PS, Wander MJ, Bowling AP, Laible PD, Gellman SH. Glycotripod amphiphiles for solubilization and stabilization of a membrane-protein superassembly: Importance of branching in the hydrophilic portion. Chembiochem. 2008;9:1706-1709. |
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Choi SH, Guzei IA, Spencer LC, Gellman SH. Crystallographic characterization of helical secondary structures in alpha/beta-peptides with 1 : 1 residue alternation. Journal of the American Chemical Society. 2008;130:6544-6550. |
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Epand RF, Mowery BP, Lee SE, Stahl SS, Lehrer RI, Gellman SH, et al. Dual mechanism of bacterial lethality for a cationic sequence-random copolymer that mimics host-defense antimicrobial peptides. Journal of Molecular Biology. 2008;379:38-50. |
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Freire F, Fisk JD, Peoples AJ, Ivancic M, Guzei IA, Gellman SH. Diacid linkers that promote parallel beta-sheet secondary structure in water. Journal of the American Chemical Society. 2008;130:7839-+. |
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Hadley EB, Testa OD, Woolfson DN, Gellman SH. Preferred side-chain constellations at antiparallel coiled-coil interfaces. Proceedings of the National Academy of Sciences of the United States of America. 2008;105:530-535. |
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Horne SW, Boersma MD, Windsor MA, Gellman SH. Sequence-based design of alpha/beta-peptide foldamers that mimic BH3 domains. Angewandte Chemie-International Edition. 2008;47:2853-2856. |
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Horne WS, Gellman SH. Foldamers with Heterogeneous Backbones. Accounts of Chemical Research. 2008;41:1399-1408. |
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Horne SW, Price JL, Gellman SH. Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly. Proceedings of the National Academy of Sciences of the United States of America. 2008;105:9151-9156. |
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Lee MR, Stahl SS, Gellman SH. Synthesis of beta-Lactams Bearing Functionalized Side Chains from a Readily Available Precursor. Organic Letters. 2008;10:5317-5319. |
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Miller CA, Gellman SH, Abbott NL, De Pablo JJ. Mechanical stability of helical beta-peptides and a comparison of explicit and implicit solvent models. Biophysical Journal. 2008;95:3123-3136. |
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Miller CA, Hernandez-Ortiz JP, Abbott NL, Gellman SH, De Pablo JJ. Dipole-induced self-assembly of helical beta-peptides. Journal of Chemical Physics. 2008;129. |
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Murray JK, Sadowsky JD, Scalf M, Smith LM, Tomita Y, Gellman SH. Exploration of structure - Activity relationships among foldamer ligands for a specific protein binding site via parallel and split-and-mix library synthesis. Journal of Combinatorial Chemistry. 2008;10:204-215. |
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Peterson KJ, Sadowsky JD, Scheef EA, Pal S, Kourentzi KD, Willson RC, et al. A fluorescence polarization assay for identifying ligands that bind to vascular endothelial growth factor. Analytical Biochemistry. 2008;378:8-14. |
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Pizzey CL, Pomerantz WC, Sung B-J, Yuwono VM, Gellman SH, Hartgerink JD, et al. Characterization of nanofibers formed by self-assembly of beta-peptide oligomers using small angle x-ray scattering. Journal of Chemical Physics. 2008;129. |
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Pomerantz WC, Yuwono VM, Pizzey CL, Hartgerink JD, Abbott NL, Gellman SH. Nanofibers and lyotropic liquid crystals from a class of self-assembling beta-peptides. Angewandte Chemie-International Edition. 2008;47:1241-1244. |
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Vaz E, Pomerantz WC, Geyer M, Gellman SH, Brunsveld L. Comparison of Design Strategies for Promotion of beta-Peptide 14-Helix Stability in Water. Chembiochem. 2008;9:2254-2259. |
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Pomerantz WC, Grygiel TLR, Lai JR, Gellman SH. Distinctive Circular Dichroism Signature for 14-Helix-Bundle Formation by β-Peptides. Organic Letters [Internet]. 2008;10:1799-1802. Available from: http://pubs.acs.org/doi/abs/10.1021/ol800622e |
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Zhu X, Koenig P, Gellman SH, Yethiraj A, Cui Q. Establishing Effective Simulation Protocols for β- and α/β-Peptides. II. Molecular Mechanical (MM) Model for a Cyclic β-Residue. The Journal of Physical Chemistry B [Internet]. 2008;112:5439-5448. Available from: http://pubs.acs.org/doi/abs/10.1021/jp077601y |
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Chi Y, Guo L, Kopf NA, Gellman SH. Enantioselective organocatalytic Michael addition of aldehydes to nitroethylene: efficient access to gamma2-amino acids. J Am Chem Soc. 2008;130(17):5608-9. |
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Peterson KJ, Sadowsky JD, Scheef EA, Pal S, Kourentzi KD, Willson RC, et al. A fluorescence polarization assay for identifying ligands that bind to vascular endothelial growth factor. Anal Biochem. 2008;378(1):8-14. |
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Kissounko DA, Hoerter JM, Guzei IA, Cui Q, Gellman SH, Stahl SS. Ti-IV-mediated reactions between primary amines and secondary carboxamides: Amidine formation versus transamidation. Journal of the American Chemical Society. 2007;129:1776-1783. |
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Bell CM, Kissounko DA, Gellman SH, Stahl SS. Catalytic metathesis of simple secondary amides. Angewandte Chemie-International Edition. 2007;46:761-763. |
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Chi Y, English EP, Pomerantz WC, Horne SW, Joyce LA, Alexander LR, et al. Practical synthesis of enantiomerically pure beta(2)-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes. Journal of the American Chemical Society. 2007;129:6050-6055. |
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Choi SH, Guzei IA, Gellman SH. Helical secondary structures in alpha/beta-peptides by crystallographic characterization. Biopolymers. 2007;88:607-607. |
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Choi SH, Guzei IA, Gellman SH. Crystallographic Characterization of the alpha/ss-Peptide 14/15-Helix. Journal of the American Chemical Society. 2007;129:13780-+. |
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Cornilescu G, Hadley EB, Woll MG, Markley JL, Gellman SH, Cornilescu CC. Solution structure of a small protein containing a fluorinated side chain in the core. Protein Science. 2007;16:14-19. |
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Mowery BP, Lee SE, Kissounko DA, Epand RF, Epand RM, Weisblum B, et al. Mimicry of antimicrobial host-defense peptides by random copolymers. Journal of the American Chemical Society. 2007;129:15474-+. |
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Murray JK, Gellman SH. Targeting protein-protein interactions: Lessons from p53/MDM2. Biopolymers. 2007;88:657-686. |
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Murray JK, Gellman SH. Parallel synthesis of peptide libraries using microwave irradiation. Nature Protocols. 2007;2:624-631. |
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Pomerantz WC, Cadwell KD, Hsu Y-J, Gellman SH, Abbott NL. Sequence dependent behavior of amphiphilic beta-peptides on gold surfaces. Chemistry of Materials. 2007;19:4436-4441. |
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Pomerantz WC, Pizzey C, Yuwono V, Paramanov S, Hartgerink J, Gellman SH, et al. Lyotropic liquid crystals from designed helical beta peptides. Biopolymers. 2007;88:570-570. |
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Potocky TB, Silvius J, Menon AK, Gellman SH. HeLa cell entry by guanidinium-rich beta-peptides: Importance of specific cation-cell surface interactions. Chembiochem. 2007;8:917-926. |
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Price JL, Home WS, Gellman SH. Heterogeneous helix-bundle quaternary structure formed by alpha/beta-peptide foldamers and alpha-peptides. Biopolymers. 2007;88:568-568. |
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Price JL, Horne SW, Gellman SH. Discrete heterogeneous quaternary structure formed by alpha/beta-peptide foldamers and alpha-peptides. Journal of the American Chemical Society. 2007;129:6376-+. |
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Sadowsky JD, Douglas Fairlie W, Hadley EB, Lee H-S, Umezawa N, Nikolovska-Coleska Z, et al. (alpha/beta+alpha)-Peptide antagonists of BH3 Domain/Bcl-x(L) recognition: Toward general strategies for foldamer-based inhibition of protein-protein interactions. Journal of the American Chemical Society. 2007;129:139-154. |
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Sadowsky JD, Murray JK, Tomita Y, Gellman SH. Exploration of backbone space in foldamers containing alpha- and beta-amino acid residues: Developing protease-resistant oligomers that bind tightly to the BH3-recognition cleft of Bcl-x(L). Chembiochem. 2007;8:903-916. |
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Schmitt MA, Weisblum B, Gellman SH. Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides. Journal of the American Chemical Society. 2007;129:417-428. |
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Horne SW, Price JL, Keck JL, Gellman SH. Helix Bundle Quaternary Structure from α/β-Peptide Foldamers. Journal of the American Chemical Society [Internet]. 2007;129:4178-4180. Available from: http://pubs.acs.org/doi/abs/10.1021/ja070396f |
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Lee M-R, Raguse TL, Schinnerl M, Pomerantz WC, Wang X, Wipf P, et al. Origins of the high 14-helix propensity of cyclohexyl-rigidified residues in beta-peptides. Org Lett. 2007;9(9):1801-4. |
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Tang L, Hopper ED, Tong Y, Sadowsky JD, Peterson KJ, Gellman SH, et al. H/D exchange- and mass spectrometry-based strategy for the thermodynamic analysis of protein-ligand binding. Anal Chem. 2007;79(15):5869-77. |
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Hadley EB, Witek AM, Freire F, Peoples AJ, Gellman SH. Thermodynamic analysis of beta-sheet secondary structure by backbone thioester exchange. Angew Chem Int Ed Engl. 2007;46(37):7056-9. |
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Yu SM, McQuade DT, Quinn MA, Hackenberger CPR, Krebs MP, Polans AS, et al. An improved tripod amphiphile for membrane protein solubilization. Protein Science. 2006;8:58-65. |
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Pal S, Wu J, Murray JK, Gellman SH, Wozniak MA, Keely PJ, et al. An antiangiogenic neurokinin-B/thromboxane A2 regulatory axis. Journal of Cell Biology. 2006;174:1047. |
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Rathore N, Gellman SH, de Pablo JJ. Thermodynamic stability of beta-peptide helices and the role of cyclic residues. Biophysical Journal. 2006;91:3425-3435. |
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Schmitt MA, Choi SH, Guzei IA, Gellman SH. New helical foldamers: Heterogeneous backbones with 1 : 2 and 2 : 1 alpha :beta-amino acid residue patterns. Journal of the American Chemical Society. 2006;128:4538-4539. |
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Woll MG, Hadley EB, Mecozzi S, Gellman SH. Stabilizing and destabilizing effects of phenylalanine -> F-5-phenylalanine mutations on the folding of a small protein. Journal of the American Chemical Society. 2006;128:15932-15933. |
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Lai JR, Epand RF, Weisblum B, Epand RM, Gellman SH. Roles of salt and conformation in the biological and physicochemical behavior of protegrin-1 and designed analogues: Correlation of antimicrobial, hemolytic, and lipid bilayer-perturbing activities. Biochemistry. 2006;45:15718-15730. |
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Hadley EB, Gellman SH. An antiparallel alpha-helical coiled-coil model system for rapid assessment of side-chain recognition at the hydrophobic interface. Journal of the American Chemical Society. 2006;128:16444-16445. |
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Epand RF, Schmitt MA, Gellman SH, Epand RM. Role of membrane lipids in the mechanism of bacterial species selective toxicity by two α/β-antimicrobial peptides. Biochimica et Biophysica Acta (BBA) - Biomembranes [Internet]. 2006;1758:1343 - 1350. Available from: http://www.sciencedirect.com/science/article/pii/S0005273606000356 |
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English EP, Chumanov RS, Gellman SH, Compton T. Rational development of beta-peptide inhibitors of human cytomegalovirus entry. J Biol Chem. 2006;281(5):2661-7. |
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Murray JK, Gellman SH. Microwave-assisted parallel synthesis of a 14-helical beta-peptide library. J Comb Chem. 2006;8(1):58-65. |
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Hoerter JM, Otte KM, Gellman SH, Stahl SS. Mechanism of Al(III)-catalyzed transamidation of unactivated secondary carboxamides. J Am Chem Soc. 2006;128(15):5177-83. |
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Chi Y, Gellman SH. Enantioselective organocatalytic aminomethylation of aldehydes: a role for ionic interactions and efficient access to beta2-amino acids. J Am Chem Soc. 2006;128(21):6804-5. |
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Fisk JD, Schmitt MA, Gellman SH. Thermodynamic analysis of autonomous parallel beta-sheet formation in water. J Am Chem Soc. 2006;128(22):7148-9. |
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Pomerantz WC, Abbott NL, Gellman SH. Lyotropic liquid crystals from designed helical beta-peptides. J Am Chem Soc. 2006;128(27):8730-1. |
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Karlsson AJ, Pomerantz WC, Weisblum B, Gellman SH, Palecek SP. Antifungal activity from 14-helical beta-peptides. J Am Chem Soc. 2006;128(39):12630-1. |
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Lai JR, Epand RF, Weisblum B, Epand RM, Gellman SH. Roles of salt and conformation in the biological and physicochemical behavior of protegrin-1 and designed analogues: correlation of antimicrobial, hemolytic, and lipid bilayer-perturbing activities. Biochemistry. 2006;45(51):15718-30. |
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Hadley EB, Gellman SH. An antiparallel alpha-helical coiled-coil model system for rapid assessment of side-chain recognition at the hydrophobic interface. J Am Chem Soc. 2006;128(51):16444-5. |
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De Stasio G, Schmitt MA, Gellman SH. Spectromicroscopy at the organic-inorganic interface in biominerals. American Journal of Science. 2005;305:673-686. |
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Gelman MA, Gellman SH. Using constrained b-amino acid residues to control b-peptide shape and function. Enantioselective Synthesis of b-Amino Acids (2nd Edition). 2005;:527-591. |
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Gellman SH. Structure and function in foldamers. Polymer Preprints (American Chemical Society, Division of Polymer Chemistry). 2005;46:169. |
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Kissounko DA, Guzei IA, Gellman SH, Stahl SS. Titanium(IV)-Mediated Conversion of Carboxamides to Amidines and Implications for Catalytic Transamidation. Organometallics. 2005;24:5208-5210. |
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Schmitt MA, Choi SH, Guzei IA, Gellman SH. Residue Requirements for Helical Folding in Short α/β-Peptides: Crystallographic Characterization of the 11-Helix in an Optimized Sequence. Journal of the American Chemical Society [Internet]. 2005;127:13130-13131. Available from: http://pubs.acs.org/doi/abs/10.1021/ja0536163 |
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Potocky TB, Menon AK, Gellman SH. Effects of conformational stability and geometry of guanidinium display on cell entry by beta-peptides. J Am Chem Soc. 2005;127(11):3686-7. |
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Espinosa JF, Syud FA, Gellman SH. An autonomously folding beta-hairpin derived from the human YAP65 WW domain: attempts to define a minimum ligand-binding motif. Biopolymers. 2005;80(2-3):303-11. |
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Murray JK, Gellman SH. Application of microwave irradiation to the synthesis of 14-helical beta-peptides. Org Lett. 2005;7(8):1517-20. |
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Huck BR, Gellman SH. Synthesis of 2,2-disubstituted pyrrolidine-4-carboxylic acid derivatives and their incorporation into beta-peptide oligomers. J Org Chem. 2005;70(9):3353-62. |
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Eldred SE, Pancost MR, Otte KM, Rozema D, Stahl SS, Gellman SH. Effects of side chain configuration and backbone spacing on the gene delivery properties of lysine-derived cationic polymers. Bioconjug Chem. 2005;16(3):694-9. |
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Theisen MJ, Potocky TB, McQuade TD, Gellman SH, Chiu ML. Crystallization of bacteriorhodopsin solubilized by a tripod amphiphile. Biochim Biophys Acta. 2005;1751(2):213-6. |
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Chi Y, Peelen TJ, Gellman SH. A rapid 1H NMR assay for enantiomeric excess of alpha-substituted aldehydes. Org Lett. 2005;7(16):3469-72. |
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Porter EA, Weisblum B, Gellman SH. Use of parallel synthesis to probe structure-activity relationships among 12-helical beta-peptides: evidence of a limit on antimicrobial activity. J Am Chem Soc. 2005;127(32):11516-29. |
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Peelen TJ, Chi Y, Gellman SH. Enantioselective organocatalytic Michael additions of aldehydes to enones with imidazolidinones: cocatalyst effects and evidence for an enamine intermediate. J Am Chem Soc. 2005;127(33):11598-9. |
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Sadowsky JD, Schmitt MA, Lee H-S, Umezawa N, Wang S, Tomita Y, et al. Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition. J Am Chem Soc. 2005;127(34):11966-8. |
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Chi Y, Gellman SH. Diphenylprolinol methyl ether: a highly enantioselective catalyst for Michael addition of aldehydes to simple enones. Org Lett. 2005;7(19):4253-6. |
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Murray JK, Farooqi B, Sadowsky JD, Scalf M, Freund WA, Smith LM, et al. Efficient synthesis of a beta-peptide combinatorial library with microwave irradiation. J Am Chem Soc. 2005;127(38):13271-80. |
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Epand RF, Schmitt MA, Gellman SH, Sen A, Auger M, Hughes DW, et al. Bacterial species selective toxicity of two isomeric alpha/beta-peptides: role of membrane lipids. Mol Membr Biol. 2005;22(6):457-69. |
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Hayen A, Schmitt MA, Ngassa FN, Thomasson KA, Gellman SH. Two helical conformations from a single foldamer backbone: "split personality" in short alpha/beta-peptides. Angew Chem Int Ed Engl. 2004;43(4):505-10. |
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Gelman MA, Weisblum B, Lynn DM, Gellman SH. Biocidal activity of polystyrenes that are cationic by virtue of protonation. Org Lett. 2004;6(4):557-60. |
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Langenhan JM, Gellman SH. Effects of alternative side chain pairings and reverse turn sequences on antiparallel sheet structure in beta-peptide hairpins. Org Lett. 2004;6(6):937-40. |
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Schmitt MA, Weisblum B, Gellman SH. Unexpected relationships between structure and function in alpha,beta-peptides: antimicrobial foldamers with heterogeneous backbones. J Am Chem Soc. 2004;126(22):6848-9. |
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Epand RF, Raguse TL, Gellman SH, Epand RM. Antimicrobial 14-helical beta-peptides: potent bilayer disrupting agents. Biochemistry. 2004;43(29):9527-35. |
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Lai JR, Fisk JD, Weisblum B, Gellman SH. Hydrophobic core repacking in a coiled-coil dimer via phage display: insights into plasticity and specificity at a protein-protein interface. J Am Chem Soc. 2004;126(34):10514-5. |
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Woll MG, Gellman SH. Backbone thioester exchange: a new approach to evaluating higher order structural stability in polypeptides. J Am Chem Soc. 2004;126(36):11172-4. |
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Peelen TJ, Chi Y, English EP, Gellman SH. Synthesis of 4,4-disubstituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into 12-helical beta-peptides. Org Lett. 2004;6(24):4411-4. |
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Gellman SH. Structure and function in b-peptide foldamers. Polymer Preprints (American Chemical Society, Division of Polymer Chemistry). 2003;44:461. |
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Brückner A M, Garcia M, Marsh A, Gellman SH, Diederichsen U. Synthesis of Novel Nucleo-β-Amino Acids and Nucleobase-Functionalized β-Peptides. European Journal of Organic Chemistry [Internet]. 2003;2003:3555–3561. Available from: http://dx.doi.org/10.1002/ejoc.200300269 |
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Schinnerl M, Murray J K, Langenhan J M, Gellman SH. Asymmetric Synthesis of a New Helix-Forming β-Amino Acid: trans-4-Aminopiperidine-3-carboxylic Acid. European Journal of Organic Chemistry [Internet]. 2003;2003:721–726. Available from: http://dx.doi.org/10.1002/ejoc.200390112 |
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Syud FA, Stanger HE, Mortell HS, Espinosa JF, Fisk JD, Fry CG, et al. Influence of strand number on antiparallel beta-sheet stability in designed three- and four-stranded beta-sheets. J Mol Biol. 2003;326(2):553-68. |
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Lee H-S, Park J-S, Kim BM, Gellman SH. Efficient synthesis of enantiomerically pure beta2-amino acids via chiral isoxazolidinones. J Org Chem. 2003;68(4):1575-8. |
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Lai JR, Gellman SH. Reinvestigation of the proposed folding and self-association of the Neuropeptide Head Activator. Protein Sci. 2003;12(3):560-6. |
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Epand RF, Umezawa N, Porter EA, Gellman SH, Epand RM. Interactions of the antimicrobial beta-peptide beta-17 with phospholipid vesicles differ from membrane interactions of magainins. Eur J Biochem. 2003;270(6):1240-8. |
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Eldred SE, Stone DA, Gellman SH, Stahl SS. Catalytic transamidation under moderate conditions. J Am Chem Soc. 2003;125(12):3422-3. |
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Raguse TL, Lai JR, Gellman SH. Environment-independent 14-helix formation in short beta-peptides: striking a balance between shape control and functional diversity. J Am Chem Soc. 2003;125(19):5592-3. |
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Langenhan JM, Guzei IA, Gellman SH. Parallel sheet secondary structure in beta-peptides. Angew Chem Int Ed Engl. 2003;42(21):2402-5. |
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Park J-S, Lee H-S, Lai JR, Kim BM, Gellman SH. Accommodation of alpha-substituted residues in the beta-peptide 12-helix: expanding the range of substitution patterns available to a foldamer scaffold. J Am Chem Soc. 2003;125(28):8539-45. |
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Langenhan JM, Gellman SH. Preparation of protected syn-alpha,beta-dialkyl beta-amino acids that contain polar side chain functionality. J Org Chem. 2003;68(16):6440-3. |
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Brückner AM, Chakraborty P, Gellman SH, Diederichsen U. Molecular architecture with functionalized beta-peptide helices. Angew Chem Int Ed Engl. 2003;42(36):4395-9. |
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Gelman MA, Richter S, Cao H, Umezawa N, Gellman SH, Rana TM. Selective binding of TAR RNA by a Tat-derived beta-peptide. Org Lett. 2003;5(20):3563-5. |
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Potocky TB, Menon AK, Gellman SH. Cytoplasmic and nuclear delivery of a TAT-derived peptide and a beta-peptide after endocytic uptake into HeLa cells. J Biol Chem. 2003;278(50):50188-94. |
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Huck BR, Fisk JD, Guzei IA, Carlson HA, Gellman SH. Secondary structural preferences of 2,2-disubstituted pyrrolidine-4-carboxylic acid oligomers: beta-peptide foldamers that cannot form internal hydrogen bonds. J Am Chem Soc. 2003;125(30):9035-7. |
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Raguse T L, Lai J R, Gellman SH. Evidence that the β-Peptide 14-Helix is Stabilized by β3-Residues with Side-Chain Branching Adjacent to the β-Carbon Atom. Helvetica Chimica Acta [Internet]. 2002;85:4154–4164. Available from: http://dx.doi.org/10.1002/hlca.200290001 |
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Knight SMG, Umezawa N, Lee H-S, Gellman SH, Kay BK. A fluorescence polarization assay for the identification of inhibitors of the p53-DM2 protein-protein interaction. Anal Biochem. 2002;300(2):230-6. |
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Umezawa N, Gelman MA, Haigis MC, Raines RT, Gellman SH. Translocation of a beta-peptide across cell membranes. J Am Chem Soc. 2002;124(3):368-9. |
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Hilario J, Kubelka J, Syud FA, Gellman SH, Keiderling TA. Spectroscopic characterization of selected beta- sheet hairpin models. Biopolymers. 2002;67(4-5):233-6. |
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Espinosa JF, Syud FA, Gellman SH. Analysis of the factors that stabilize a designed two-stranded antiparallel beta-sheet. Protein Sci. 2002;11(6):1492-505. |
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LePlae PR, Fisk JD, Porter EA, Weisblum B, Gellman SH. Tolerance of acyclic residues in the beta-peptide 12-helix: access to diverse side-chain arrays for biological applications. J Am Chem Soc. 2002;124(24):6820-1. |
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Porter EA, Weisblum B, Gellman SH. Mimicry of host-defense peptides by unnatural oligomers: antimicrobial beta-peptides. J Am Chem Soc. 2002;124(25):7324-30. |
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Arnold U, Hinderaker MP, Nilsson BL, Huck BR, Gellman SH, Raines RT. Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turn. J Am Chem Soc. 2002;124(29):8522-3. |
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Porter EA, Wang X, Schmitt MA, Gellman SH. Synthesis and 12-helical secondary structure of beta-peptides containing (2R,3R)-aminoproline. Org Lett. 2002;4(19):3317-9. |
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Lai JR, Huck BR, Weisblum B, Gellman SH. Design of non-cysteine-containing antimicrobial beta-hairpins: structure-activity relationship studies with linear protegrin-1 analogues. Biochemistry. 2002;41(42):12835-42. |
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Woll MG, Fisk JD, LePlae PR, Gellman SH. Stereoselective synthesis of 3-substituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into short 12-helical beta-peptides that fold in water. J Am Chem Soc. 2002;124(42):12447-52. |
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Raguse TL, Porter EA, Weisblum B, Gellman SH. Structure-activity studies of 14-helical antimicrobial beta-peptides: probing the relationship between conformational stability and antimicrobial potency. J Am Chem Soc. 2002;124(43):12774-85. |
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Lee HS, LePlae PR, Porter EA, Gellman SH. An efficient route to either enantiomer of orthogonally protected trans-3-aminopyrrolidine-4-carboxylic acid. J Org Chem. 2001;66(10):3597-9. |
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Fisk JD, Gellman SH. A parallel beta-sheet model system that folds in water. J Am Chem Soc. 2001;123(2):343-4. |
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McKay SL, Haptonstall B, Gellman SH. Beyond the hydrophobic effect: attractions involving heteroaromatic rings in aqueous solution. J Am Chem Soc. 2001;123(6):1244-5. |
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Lee HS, Syud FA, Wang X, Gellman SH. Diversity in short beta-peptide 12-helices: high-resolution structural analysis in aqueous solution of a hexamer containing sulfonylated pyrrolidine residues. J Am Chem Soc. 2001;123(31):7721-2. |
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Langenhan JM, Fisk JD, Gellman SH. Evaluation of hydrogen bonding complementarity between a secondary sulfonamide and an alpha-amino acid residue. Org Lett. 2001;3(16):2559-62. |
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LePlae PR, Umezawa N, Lee HS, Gellman SH. An efficient route to either enantiomer of trans-2-aminocyclopentanecarboxylic acid. J Org Chem. 2001;66(16):5629-32. |
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Syud FA, Stanger HE, Gellman SH. Interstrand side chain--side chain interactions in a designed beta-hairpin: significance of both lateral and diagonal pairings. J Am Chem Soc. 2001;123(36):8667-77. |
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Stanger HE, Syud FA, Espinosa JF, Giriat I, Muir T, Gellman SH. Length-dependent stability and strand length limits in antiparallel beta -sheet secondary structure. Proc Natl Acad Sci U S A. 2001;98(21):12015-20. |
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Cheng RP, Gellman SH, DeGrado WF. beta-Peptides: from structure to function. Chem Rev. 2001;101(10):3219-32. |
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Raguse TL, Lai JR, LePlae PR, Gellman SH. Toward beta-peptide tertiary structure: self-association of an amphiphilic 14-helix in aqueous solution. Org Lett. 2001;3(24):3963-6. |
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Fisk JD, Powell DR, Gellman SH. Control of Hairpin Formation via Proline Configuration in Parallel β-Sheet Model Systems. Journal of the American Chemical Society [Internet]. 2000;122:5443-5447. Available from: http://pubs.acs.org/doi/abs/10.1021/ja9929483 |
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Christianson LA, Lucero MJ, Appella DH, Klein DA, Gellman SH. Improved treatment of cyclic β-amino acids and successful prediction of β-peptide secondary structure using a modified force field: AMBER*C. Journal of Computational Chemistry [Internet]. 2000;21:763–773. Available from: http://dx.doi.org/10.1002/(SICI)1096-987X(20000715)21:9<763::AID-JCC5>3.0.CO;2-C |
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Chung YJ, Huck BR, Christianson LA, Stanger HE, Krauthäuser S, Powell DR, et al. Stereochemical Control of Hairpin Formation in β-Peptides Containing Dinipecotic Acid Reverse Turn Segments. Journal of the American Chemical Society [Internet]. 2000;122:3995-4004. Available from: http://pubs.acs.org/doi/abs/10.1021/ja993416p |
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Porter EA, Wang X, Lee H-S, Weisblum B, Gellman SH. Antibiotics: Non-Haemolytic β-Amino Acid Oligomers. Nature. 2000; |
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Barchi JJ, Huang X, Appella DH, Christianson LA, Durell SR, Gellman SH. Solution Conformations of Helix-Forming β-Amino Acid Homooligomers. Journal of the American Chemical Society [Internet]. 2000;122:2711-2718. Available from: http://pubs.acs.org/doi/abs/10.1021/ja9930014 |
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McQuade DT, Quinn MA, Yu SM, Polans AS, Krebs MP, Gellman SH. Rigid Amphiphiles for Membrane Protein Manipulation. Angew Chem Int Ed Engl. 2000;39(4):758-761. |
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Gardner RR, McKay SL, Gellman SH. Solvent-dependent stabilization of the E configuration of propargylic secondary amides. Org Lett. 2000;2(15):2335-8. |
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Espinosa JF, Gellman SH. A Designed beta-Hairpin Containing a Natural Hydrophobic Cluster. Angew Chem Int Ed Engl. 2000;39(13):2330-2333. |
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Appella DH, LePlae PR, Raguse TL, Gellman SH. (R,R,R)-2,5-diaminocylohexanecarboxylic acid, a building block for water-soluble, helix-forming beta-peptides. J Org Chem. 2000;65(15):4766-9. |
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Huck BR, Fisk JD, Gellman SH. Promotion of sheet formation in alpha-peptide strands by a beta-peptide reverse turn. Org Lett. 2000;2(17):2607-10. |
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Yu SM, McQuade DT, Quinn MA, Hackenberger CP, Krebs MP, Polans AS, et al. An improved tripod amphiphile for membrane protein solubilization. Protein Sci. 2000;9(12):2518-27. |
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Appella DH, Barchi JJ, Durell SR, Gellman SH. Formation of short, stable helices in aqueous solution by beta-amino acid hexamers. Journal of the American Chemical Society. 1999;121:2309-2310. |
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Appella DH, Christianson LA, Karle IL, Powell DR, Gellman SH. Synthesis and characterization of trans-2-aminocyclohexanecarboxylic acid oligomers: An unnatural helical secondary structure and implications for beta-peptide tertiary structure. Journal of the American Chemical Society. 1999;121:6206-6212. |
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Appella DH, Christianson LA, Klein DA, Richards MR, Powell DR, Gellman SH. Synthesis and structural characterization of helix-forming beta-peptides: trans-2-aminocyclopentanecarboxylic acid oligomers. Journal of the American Chemical Society. 1999;121:7574-7581. |
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Daugherty DL, Gellman SH. A fluorescence assay for leucine zipper dimerization: Avoiding unintended consequences of fluorophore attachment. Journal of the American Chemical Society. 1999;121:4325-4333. |
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Gardner RR, Liang GB, Gellman SH. beta-turn and beta-hairpin mimicry with tetrasubstituted alkenes. Journal of the American Chemical Society. 1999;121:1806-1816. |
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Huck BR, Langenhan JM, Gellman SH. Non-hydrogen-bonded secondary structure in beta-peptides: Evidence from circular dichroism of (S)-pyrrolidine-3-carboxylic acid oligomers and (S)-nipecotic acid oligomers. Organic Letters. 1999;1:1717-1720. |
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Syud FA, Espinosa JF, Gellman SH. NMR-based quantification of beta-sheet populations in aqueous solution through use of reference peptides for the folded and unfolded states. Journal of the American Chemical Society. 1999;121:11577-11578. |
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Yang JH, Christianson LA, Gellman SH. Comparison of an HXH three-center hydrogen bond with alternative two-center hydrogen bonds in a model system. Organic Letters. 1999;1:11-13. |
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Applequist J, Bode KA, Appella DH, Christianson LA, Gellman SH. Theoretical and experimental circular dichroic spectra of the novel helical foldamer poly (1R,2R)-trans-2-aminocyclopentanecarboxylic acid. Journal of the American Chemical Society. 1998;120:4891-4892. |
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Chung YJ, Christianson LA, Stanger HE, Powell DR, Gellman SH. A beta-peptide reverse turn that promotes hairpin formation. Journal of the American Chemical Society. 1998;120:10555-10556. |
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Daugherty DL, Rozema D, Hanson PE, Gellman SH. Artificial chaperone-assisted refolding of citrate synthase. Journal of Biological Chemistry. 1998;273:33961-33971. |
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Gellman SH. Foldamers: A manifesto. Accounts of Chemical Research. 1998;31:173-180. |
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Gellman SH. Minimal model systems for beta sheet secondary structure in proteins. Current Opinion in Chemical Biology. 1998;2:717-725. |
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Hanson PE, Gellman SH. Mechanistic comparison of artificial-chaperone-assisted and unassisted refolding of urea-denatured carbonic anhydrase B. Folding and Design. 1998;3:457-468. |
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Schenck HL, Gellman SH. Use of a designed triple-stranded antiparallel beta-sheet to probe beta-sheet cooperativity in aqueous solution. Journal of the American Chemical Society. 1998;120:4869-4870. |
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Stanger HE, Gellman SH. Rules for antiparallel beta-sheet design: D-Pro-Gly is superior to L-Asn-Gly for beta-hairpin nucleation. Journal of the American Chemical Society. 1998;120:4236-4237. |
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Yang JH, Gellman SH. Energetic superiority of two-center hydrogen bonding relative to three-center hydrogen bonding in a model system. Journal of the American Chemical Society. 1998;120:9090-9091. |
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Gellman SH. Minimal model systems for beta sheet secondary structure in proteins. Curr Opin Chem Biol. 1998;2(6):717-25. |
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Appella DH, Christianson LA, Klein DA, Powell DR, Huang XL, Barchi JJ, et al. Residue-based control of helix shape in beta-peptide oligomers. Nature. 1997;387:381-384. |
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Gardner RR, Christianson LA, Gellman SH. Quantitative analysis of hydrophobically induced folding in a minimal model system. Journal of the American Chemical Society. 1997;119:5041-5042. |
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Gardner RR, Gellman SH. Secondary effects in flexible hydrogen bonding networks. Tetrahedron. 1997;53:9881-9890. |
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Gellman SH, Cowburn D, McDonnell JM. Hairpin turns. Chemical & Engineering News. 1997;75:6-6. |
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Haque TS, Gellman SH. Insights on beta-hairpin stability in aqueous solution from peptides with enforced type I' and type II' beta-turns. Journal of the American Chemical Society. 1997;119:2303-2304. |
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Holmgren SK, Savage PB, Desper JM, Schladetzky KD, Powell DR, Gellman SH. Steric control of oxidation selectivity in macrocyclic phosphine oxide-dithioethers. Tetrahedron. 1997;53:12249-12262. |
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Krauthauser S, Christianson LA, Powell DR, Gellman SH. Antiparallel sheet formation in beta-peptide foldamers: Effects of beta-amino acid substitution on conformational preference. Journal of the American Chemical Society. 1997;119:11719-11720. |
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McQuade DT, McKay SL, Powell DR, Gellman SH. Indifference to hydrogen bonding in a family of secondary amides. Journal of the American Chemical Society. 1997;119:8528-8532. |
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Yang J, Christianson LA, Gellman SH. Energetic superiority of two-center over three-center (bifurcated) hydrogen bonds in solution. FASEB Journal. 1997;11:A1324-A1324. |
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Appella DH, Christianson LA, Karle IL, Powell DR, Gellman SH. beta-peptide foldamers: Robust Helix formation in a new family of beta-amino acid oligomers. Journal of the American Chemical Society. 1996;118:13071-13072. |
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Gellman SH, Haque TS, Newcomb LF. New evidence that the hydrophobic effect and dispersion are not major driving forces for nucleotide base stacking. Biophysical Journal. 1996;71:3523-3525. |
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Haque TS, Little JC, Gellman SH. Stereochemical requirements for beta-hairpin formation: Model studies with four-residue peptides and depsipeptides. Journal of the American Chemical Society. 1996;118:6975-6985. |
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Rozema D, Gellman SH. Artificial chaperone-assisted refolding of carbonic anhydrase B. Journal of Biological Chemistry. 1996;271:3478-3487. |
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Rozema D, Gellman SH. Artificial chaperone-assisted refolding of denatured-reduced lysozyme: Modulation of the competition between renaturation and aggregation. Biochemistry. 1996;35:15760-15771. |
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Schenck HL, Dado GP, Gellman SH. Redox-triggered secondary structure changes in the aggregated states of a designed methionine-rich peptide. Journal of the American Chemical Society. 1996;118:12487-12494. |
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Powell DR, Hanson PE, Gellman SH. {(ıt Z})-2-(Benzoyl-ıt aci}-nitro)-2-phenylacetonitrile}. Acta Crystallographica Section C [Internet]. 1996;52:2945–2946. Available from: http://dx.doi.org/10.1107/S0108270196010827 |
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Gardner RR, Gellman SH. EVALUATION OF THE CONFORMATION-DIRECTING EFFECTS OF SECONDARY HYDROGEN-BONDING INTERACTIONS IN FLEXIBLE TETRAPEPTIDE ANALOGS. Journal of the American Chemical Society. 1995;117:10411-10412. |
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Gardner RR, Liang GB, Gellman SH. AN ACHIRAL DIPEPTIDE MIMETIC THAT PROMOTES BETA-HAIRPIN FORMATION. Journal of the American Chemical Society. 1995;117:3280-3281. |
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McQuade DT, Barrett DG, Desper JM, Hayashi RK, Gellman SH. EFFECTS OF AMPHIPHILIC TOPOLOGY ON SELF-ASSOCIATION IN SOLUTION, AT THE AIR-WATER-INTERFACE, AND IN THE SOLID-STATE. Journal of the American Chemical Society. 1995;117:4862-4869. |
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Newcomb LF, Haque TS, Gellman SH. SEARCHING FOR MINIMUM INCREMENTS OF HYDROPHOBIC COLLAPSE - FLEXIBLE DINAPHTHYL CARBOXYLATES. Journal of the American Chemical Society. 1995;117:6509-6519. |
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Rozema D, Gellman SH. ARTIFICIAL CHAPERONES - PROTEIN REFOLDING VIA SEQUENTIAL USE OF DETERGENT AND CYCLODEXTRIN. Journal of the American Chemical Society. 1995;117:2373-2374. |
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Schladetzky KD, Haque TS, Gellman SH. STRUCTURAL CHARACTERIZATION OF THIOCYCLOPHANES THAT PROMOTE EDGE-TO-FACE AROMATIC-AROMATIC GEOMETRIES. Journal of Organic Chemistry. 1995;60:4108-4113. |
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Barrett DG, Gellman SH. ELECTROPHILE-INDUCED BERSON-WILLCOTT REARRANGEMENT OF 11-CARBOXYL-1,6-METHANO 10 ANNULENE METHYL-ESTER. Tetrahedron Letters. 1994;35:2299-2300. |
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Barrett DG, Liang GB, McQuade DT, Desper JM, Schladetzky KD, Gellman SH. SYNTHETIC STUDIES ON THE 1,6-METHANO 10 ANNULENE SKELETON - A NEW ROUTE THAT PROVIDES DERIVATIVES SUBSTITUTED AT THE BRIDGE AND ON THE ANNULENE RING. Journal of the American Chemical Society. 1994;116:10525-10532. |
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Dado GP, Gellman SH. INTRAMOLECULAR HYDROGEN-BONDING IN DERIVATIVES OF BETA-ALANINE AND GAMMA-AMINO BUTYRIC-ACID - MODEL STUDIES FOR THE FOLDING OF UNNATURAL POLYPEPTIDE BACKBONES. Journal of the American Chemical Society. 1994;116:1054-1062. |
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Desper JM, Gellman SH. STRATEGIES FOR NONMACROCYCLIC POLYTHIOETHER LIGANDS - NEW PENTACOORDINATING ARCHITECTURES. Angewandte Chemie-International Edition in English. 1994;33:319-321. |
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Gallo EA, Gellman SH. EFFECT OF A C-TERMINAL CATIONIC GROUP ON THE COMPETITION BETWEEN ALPHA-HELICAL TURN AND BETA-TURN IN A MODEL DEPSIPEPTIDE. Journal of the American Chemical Society. 1994;116:11560-11561. |
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Haque TS, Little JC, Gellman SH. MIRROR-IMAGE REVERSE TURNS PROMOTE BETA-HAIRPIN FORMATION. Journal of the American Chemical Society. 1994;116:4105-4106. |
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Newcomb LF, Gellman SH. AROMATIC STACKING INTERACTIONS IN AQUEOUS-SOLUTION - EVIDENCE THAT NEITHER CLASSICAL HYDROPHOBIC EFFECTS NOR DISPERSION FORCES ARE IMPORTANT. Journal of the American Chemical Society. 1994;116:4993-4994. |
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Savage PB, Holmgren SK, Gellman SH. ANION AND ION-PAIR COMPLEXATION BY A MACROCYCLIC PHOSPHINE OXIDE DISULFOXIDE. Journal of the American Chemical Society. 1994;116:4069-4070. |
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Skwierczynski RD, Gellman SH. ON THE HYDROGEN-BONDED STATUS OF 2-AZACYCLONONANONE AND 2-AZACYCLOTRIDECANONE IN THE SOLID-STATE. Journal of Physical Chemistry. 1994;98:3694-3696. |
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Barrett DG, Gellman SH. EFFECTS OF AMPHIPHILE TOPOLOGY ON AGGREGATION PROPERTIES - DISTINCTIVE BEHAVIOR OF CONTRAFACIAL AMPHIPHILES. Journal of the American Chemical Society. 1993;115:9343-9344. |
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Dado GP, Gellman SH. STRUCTURAL AND THERMODYNAMIC CHARACTERIZATION OF TEMPERATURE-DEPENDENT CHANGES IN THE FOLDING PATTERN OF A SYNTHETIC TRIAMIDE. Journal of the American Chemical Society. 1993;115:4228-4245. |
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Dado GP, Gellman SH. REDOX CONTROL OF SECONDARY STRUCTURE IN A DESIGNED PEPTIDE. Journal of the American Chemical Society. 1993;115:12609-12610. |
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Desper JM, Vyvyan JR, Mayer MJ, Ochrymowycz LA, Gellman SH. NICKEL(II) CHELATION BY 3 BICYCLIC TETRATHIOETHERS - SOLUTION AND SOLID-STATE DATA. Inorganic Chemistry. 1993;32:381-382. |
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Gallo EA, Gellman SH. HYDROGEN-BOND-MEDIATED FOLDING IN DEPSIPEPTIDE MODELS OF BETA-TURNS AND ALPHA-HELICAL TURNS. Journal of the American Chemical Society. 1993;115:9774-9788. |
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Liang GB, Desper JM, Gellman SH. EFFECTS OF BACKBONE RIGIDIFICATION ON INTRAMOLECULAR HYDROGEN-BONDING IN A FAMILY OF DIAMIDES. Journal of the American Chemical Society. 1993;115:925-938. |
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Savage PB, Gellman SH. COMPLEXATION OF HEXOSAMMONIUM IONS - EVIDENCE FOR CONTRIBUTIONS FROM OH-CENTER-DOT-CENTER-DOT-CENTER-DOT-OH HYDROGEN-BONDS IN A HYDROXYLIC MEDIUM. Journal of the American Chemical Society. 1993;115:10448-10449. |
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Savage PB, Holmgren SK, Gellman SH. OPTIMIZATION OF A PHOSPHINE OXIDE DISULFOXIDE ARRAY FOR MULTIPOINT HYDROGEN-BONDING TO AMMONIUM-IONS. Journal of the American Chemical Society. 1993;115:7900-7901. |
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Savage PB, Holmgren SK, Desper JM, Gellman SH. Macrocycles containing sulfur and phosphorus: structure and complexation properties. ChemInform. 1993;24:no–no. |
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Barrett DG, Liang GB, Gellman SH. A NEW SYNTHESIS OF METHANOBRIDGED ANNULENES - ACCESS TO HIGHLY SUBSTITUTED DERIVATIVES. Journal of the American Chemical Society. 1992;114:6915-6916. |
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Dado GP, Desper JM, Holmgren SK, Rito CJ, Gellman SH. EFFECTS OF COVALENT MODIFICATIONS ON THE SOLID-STATE FOLDING AND PACKING OF N-MALONYLGLYCINE DERIVATIVES. Journal of the American Chemical Society. 1992;114:4834-4843. |
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Dado GP, Gellman SH. ON THE USE OF AM1 CALCULATIONS FOR THE STUDY OF INTRAMOLECULAR HYDROGEN-BONDING PHENOMENA IN SIMPLE AMIDES. Journal of the American Chemical Society. 1992;114:3138-3139. |
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Gallo EA, Gellman SH. N-H--PI HYDROGEN-BONDING IN A NORBORNENYL DIAMIDE. Tetrahedron Letters. 1992;33:7485-7488. |
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Gellman SH, Powell DR, Desper JM. AN UNUSUAL HYDROGEN-BONDING PATTERN IN A CRYSTALLOGRAPHICALLY OBSERVED BETA-TURN. Tetrahedron Letters. 1992;33:1963-1964. |
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Liang GB, Rito CJ, Gellman SH. VARIATIONS IN THE TURN-FORMING CHARACTERISTICS OF N-ACYL PROLINE UNITS. Biopolymers. 1992;32:293-301. |
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Liang GB, Rito CJ, Gellman SH. THERMODYNAMIC ANALYSIS OF BETA-TURN FORMATION IN PRO-ALA, PRO-GLY, AND PRO-VAL MODEL PEPTIDES IN METHYLENE-CHLORIDE. Journal of the American Chemical Society. 1992;114:4440-4442. |
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Savage PB, Desper JM, Gellman SH. STEREOSELECTIVE OXIDATION OF AN 11-MEMBERED HETEROCYCLE. Tetrahedron Letters. 1992;33:2107-2110. |
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Stein TM, Gellman SH. SYNTHESIS AND AGGREGATION PROPERTIES OF A NEW FAMILY OF AMPHIPHILES WITH AN UNUSUAL HEADGROUP TOPOLOGY. Journal of the American Chemical Society. 1992;114:3943-3950. |
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Desper JM, Gellman SH. CRYSTALLOGRAPHIC EVIDENCE FOR MULTIPLE COORDINATING CONFORMATIONS IN A FAMILY OF MACROCYCLIC CHELATORS. Journal of the American Chemical Society. 1991;113:704-706. |
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Desper JM, Gellman SH, Wolf RE, Cooper SR. ENHANCED NICKEL(II) CHELATION BY GEM-DIMETHYL-SUBSTITUTED MACROCYCLIC TETRATHIOETHERS. Journal of the American Chemical Society. 1991;113:8663-8671. |
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Gellman SH. ON THE ROLE OF METHIONINE RESIDUES IN THE SEQUENCE-INDEPENDENT RECOGNITION OF NONPOLAR PROTEIN SURFACES. Biochemistry. 1991;30:6633-6636. |
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Gellman SH, Dado GP. ON THE USE OF MOLECULAR MECHANICS CALCULATIONS FOR THE STUDY OF INTRAMOLECULAR HYDROGEN-BONDING PHENOMENA. Tetrahedron Letters. 1991;32:7377-7380. |
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Gellman SH, Dado GP, Liang GB, Adams BR. CONFORMATION-DIRECTING EFFECTS OF A SINGLE INTRAMOLECULAR AMIDE-AMIDE HYDROGEN-BOND - VARIABLE-TEMPERATURE NMR AND IR STUDIES ON A HOMOLOGOUS DIAMIDE SERIES. Journal of the American Chemical Society. 1991;113:1164-1173. |
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Liang GB, Dado GP, Gellman SH. ANATOMY OF A STABLE INTRAMOLECULARLY HYDROGEN-BONDED FOLDING PATTERN. Journal of the American Chemical Society. 1991;113:3994-3995. |
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Gellman SH, Dado GP. On the use of molecular mechanics calculations for the study of intramolecular hydrogen bonding phenomena. Tetrahedron Letters [Internet]. 1991;32:7377 - 7380. Available from: http://www.sciencedirect.com/science/article/pii/004040399180111I |
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Dado GP, Desper JM, Gellman SH. HYDROGEN-BONDING IN A FAMILY OF TRIAMIDES - CONFORMATION-DIRECTING EFFECTS IN SOLUTION VS THE SOLID-STATE. Journal of the American Chemical Society. 1990;112:8630-8632. |
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Desper JM, Gellman SH. INCREMENTAL PREORGANIZATION OF A CHELATING MACROCYCLE. Journal of the American Chemical Society. 1990;112:6732-6734. |
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Desper JM, Powell DR, Gellman SH. MOLECULAR-STRUCTURE AND CONFORMATION OF 2 ACYCLIC POLYTHIOETHERS - IMPLICATIONS FOR THE DESIGN OF HEAVY-METAL CHELATORS. Journal of the American Chemical Society. 1990;112:4321-4324. |
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Gellman SH, Adams BR, Dado GP. TEMPERATURE-DEPENDENT CHANGES IN THE FOLDING PATTERN OF A SIMPLE TRIAMIDE. Journal of the American Chemical Society. 1990;112:460-461. |
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Gellman SH, Adams BR. INTRAMOLECULAR HYDROGEN-BONDING IN SIMPLE DIAMIDES. Tetrahedron Letters. 1989;30:3381-3384. |
