All Department Publications

Found 88 results
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Filters: Author is Blackwell, H. E.  [Clear All Filters]
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B
Blackwell HE. Bacterial crowd control with iron. Chemistry & BiologyChemistry & Biology. 2005;12:721-723.
Blackwell HE. Bacterial Crowd Control with Iron. Chemistry & Biology [Internet]. 2005;12:721 - 723. Available from: http://www.sciencedirect.com/science/article/pii/S1074552105002012
C
Blackwell HE, Zhao YD. Chemical genetic approaches to plant biology. Plant PhysiologyPlant Physiology. 2003;133:448-455.
Blackwell HE, Zhao YD. Chemical Genetic Approaches to Plant Biology. Plant Physiology [Internet]. 2003;133:448-455. Available from: http://www.plantphysiol.org/content/133/2/448.short
Praneenararat T, Palmer AG, Blackwell HE. Chemical methods to interrogate bacterial quorum sensing pathways. Org. Biomol. Chem. [Internet]. 2012;10:8189-8199. Available from: http://dx.doi.org/10.1039/C2OB26353J
Praneenararat T, Palmer AG, Blackwell HE. Chemical methods to interrogate bacterial quorum sensing pathways. Organic & Biomolecular Chemistry. 2012;10:8189-8199.
Buck ME, Breitbach AS, Belgrade SK, Blackwell HE, Lynn DM. Chemical Modification of Reactive Multilayered Films Fabricated from Poly(2-alkenyl azlactone)s: Design of Surfaces that Prevent or Promote Mammalian Cell Adhesion and Bacterial Biofilm Growth. Biomacromolecules. 2009;10:1564-1574.
Geske GD, Oneill JC, Miller DM, Wezeman RJ, Mattmann ME, Lin Q, Blackwell HE. Comparative analyses of N-acylated homoserine Lactones reveal unique structural features that dictate their ability to activate or inhibit quorum sensing. Chembiochem. 2008;9:389-400.
Stringer JR, Crapster AJ, Guzei IA, Blackwell HE. Construction of Peptoids with All Trans-Amide Backbones and Peptoid Reverse Turns via the Tactical Incorporation of N-Aryl Side Chains Capable of Hydrogen Bonding. Journal of Organic Chemistry. 2010;75:6068-6078.
Chan YY, Bian HS, Tan TMC, Mattmann ME, Geske GD, Igarashi J, Hatano T, Suga H, Blackwell HE, Chua KL. Control of quorum sensing by a Burkholderia pseudomallei multidrug efflux pump. Journal of Bacteriology. 2007;189:4320-4324.
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Palmer AG, Blackwell HE. Deciphering a protolanguage for bacteria-host communication. Nature Chemical Biology. 2008;4:452-454.
Blackwell HE, Perez L, Schreiber SL. Decoding products of diversity pathways from stock solutions derived from single polymeric macrobeads. Angewandte Chemie-International Edition. 2001;40:3421-+.
Crapster AJ, Stringer JR, Guzei IA, Blackwell HE. Design and Conformational Analysis of Peptoids Containing N-Hydroxy Amides Reveals a Unique Sheet-Like Secondary Structure. Biopolymers. 2011;96:604-616.
Fowler SA, Stacy DM, Blackwell HE. Design and synthesis of macrocyclic peptomers as mimics of a quorum sensing signal from Staphylococcus aureus. Organic Letters. 2008;10:2329-2332.
McInnis CE, Blackwell HE. Design, synthesis, and biological evaluation of abiotic, non-lactone modulators of LuxR-type quorum sensing. Bioorganic & Medicinal Chemistry. 2011;19:4812-4819.
Bowman MD, Jacobson MM, Blackwell HE. Discovery of Fluorescent Cyanopyridine and Deazalumazine Dyes Using Small Molecule Macroarrays. Organic Letters [Internet]. 2006;8:1645-1648. Available from: http://pubs.acs.org/doi/abs/10.1021/ol0602708
Bowman MD, Jacobson MM, Blackwell HE. Discovery of fluorescent cyanopyridine and deazalumazine dyes using small molecule macroarrays. Organic LettersOrganic Letters. 2006;8:1645-1648.
Spring DR, Krishnan S, Blackwell HE, Schreiber SL. Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform. Journal of the American Chemical Society. 2002;124:1354-1363.
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Campbell J, Blackwell HE. Efficient Construction of Diketopiperazine Macroarrays Through a Cyclative-Cleavage Strategy and Their Evaluation as Luminescence Inhibitors in the Bacterial Symbiont Vibrio fischeri. Journal of Combinatorial Chemistry. 2009;11:1094-1099.
Praneenararat T, Geske GD, Blackwell HE. Efficient Synthesis and Evaluation of Quorum-Sensing Modulators Using Small Molecule Macroarrays. Organic Letters. 2009;11:4600-4603.
Bowman MD, Jacobson MM, Pujanauski BG, Blackwell HE. Efficient synthesis of small molecule macroarrays: optimization of the macroarray synthesis platform and examination of microwave and conventional heating methods. TetrahedronTetrahedron. 2006;62:4715-4727.
Bowman MD, Jacobsen M, Pujanauski BG, Blackwell HE. Efficient synthesis of small molecule macroarrays: optimization of the macroarray synthesis platform and examination of microwave and conventional heating methods. Tetrahedron [Internet]. 2006;62:4715 - 4727. Available from: http://www.sciencedirect.com/science/article/pii/S0040402006002699
Geske GD, Mattmann ME, Blackwell HE. Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators. Bioorganic & Medicinal Chemistry Letters. 2008;18:5978-5981.
Geske GD, O'Neill JC, Blackwell HE. Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria. Chemical Society Reviews. 2008;37:1432-1447.
Frei R, Breitbach AS, Blackwell HE. Expedient construction of small molecule macroarrays via sequential palladium- and copper-mediated reactions and their ex situ biological testing. Chemical Science. 2012;3:1555-1561.
Gorske BC, Jewell SA, Guerard EJ, Blackwell HE. Expedient Synthesis and Design Strategies for New Peptoid Construction. Organic Letters [Internet]. 2005;7:1521-1524. Available from: http://pubs.acs.org/doi/abs/10.1021/ol0502984
Gorske BC, Jewell SA, Guerard EJ, Blackwell HE. Expedient synthesis and design strategies for new peptoid construction. Organic LettersOrganic Letters. 2005;7:1521-1524.
Blackwell HE, Clemons PA, Schreiber SL. Exploiting site-site interactions on solid support to generate dimeric molecules. Organic Letters. 2001;3:1185-1188.
Stringer JR, Crapster AJ, Guzei IA, Blackwell HE. Extraordinarily Robust Polyproline Type I Peptoid Helices Generated via the Incorporation of α-Chiral Aromatic N-1-Naphthylethyl Side Chains. Journal of the American Chemical Society [Internet]. 2011;133:15559-15567. Available from: http://pubs.acs.org/doi/abs/10.1021/ja204755p
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Grozinger CM, Chao ED, Blackwell HE, Moazed D, Schreiber SL. Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening. Journal of Biological Chemistry. 2001;276:38837-38843.
Borlee BR, Geske GD, Blackwell HE, Handelsman J. Identification of Synthetic Inducers and Inhibitors of the Quorum-Sensing Regulator LasR in Pseudomonas aeruginosa by High-Throughput Screening. Applied and Environmental Microbiology. 2010;76:8255-8258.
Stringer JR, Bowman MD, Weisblum B, Blackwell HE. Improved Small-Molecule Macroarray Platform for the Rapid Synthesis and Discovery of Antibacterial Chalcones. ACS Combinatorial Science. 2011;13:175-180.
Gorske BC, Blackwell HE. Interception of quorum sensing in Staphylococcus aureus: a new niche for peptidomimetics. Org. Biomol. Chem. [Internet]. 2006;4:1441-1445. Available from: http://dx.doi.org/10.1039/B517681F
Gorske BC, Blackwell HE. Interception of quorum sensing in Staphylococcus aureus: a new niche for peptidomimetics (vol 4, pg 1441, 2006). Organic & Biomolecular ChemistryOrganic & Biomolecular Chemistry. 2006;4:2050.
Blackwell HE, Fuqua C. Introduction to Bacterial Signals and Chemical Communication. Chemical Reviews. 2011;111:1-3.
Lindemann A, Pessi G, Schaefer AL, Mattmann ME, Christensen QH, Kessler A, Hennecke H, Blackwell HE, Greenberg PE, Harwood CS. Isovaleryl-homoserine lactone, an unusual branched-chain quorum-sensing signal from the soybean symbiont Bradyrhizobium japonicum. Proceedings of the National Academy of Sciences of the United States of America. 2011;108:16765-16770.
Guzei IA, Gorske BC, Blackwell HE. {ıt N}-[1-(Penta{\-}fluoro{\-}phenyl){\-}ethyl]{\-}acetamide}. Acta Crystallographica Section C [Internet]. 2006;62:o286–o288. Available from: http://dx.doi.org/10.1107/S0108270106012121
Guzei IA, Spencer LC, Lin Q, Blackwell HE. {ıt N}-{(Amino{\-}carbon{\-}yl)[(ıt S})-4-nitro{\-}benz{\-}yl]meth{\-}yl}-ıt N}-{[(ıt R})-cyclo{\-}hexyl](cyclo{\-}hexylamino{\-}carbon{\-}yl)meth{\-}yl}propanamide methanol solvate}. Acta Crystallographica Section E [Internet]. 2007;63:o1892–o1894. Available from: http://dx.doi.org/10.1107/S1600536807012299

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