All Faculty and Research Staff Publications

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2009
Shoulders MD, Raines RT. Modulating Collagen Triple-Helix Stability with 4-Chloro, 4-Fluoro, and 4-Methylprolines. Peptides for Youth. 2009 ;611:251-252.
Choudhary A, Gandla D, Krow GR, Raines RT. Nature of Amide Carbonyl-Carbonyl Interactions in Proteins. Journal of the American Chemical Society. 2009 ;131:7244-+.
Turcotte RF, Lavis LD, Raines RT. Onconase cytotoxicity relies on the distribution of its positive charge. FEBS Journal. 2009 ;276:4270-4281.
Shoulders MD, Kamer KJ, Raines RT. Origin of the stability conferred upon collagen by fluorination. Bioorganic & Medicinal Chemistry Letters. 2009 ;19:3859-3862.
Myers EL, Raines RT. A Phosphine-Mediated Conversion of Azides into Diazo Compounds. Angewandte Chemie-International Edition. 2009 ;48:2359-2363.
Tam A, Raines RT. Protein Engineering with the Traceless Staudinger Ligation. Methods in Enzymology. 2009 ;462:25-44.
Allen MJ, Wangkanont K, Raines RT, Kiessling LL. ROMP from ROMP: A New Approach to Graft Copolymer Synthesis. Macromolecules. 2009 ;42:4023-4027.
Dickson KA, Raines RT. Silencing an Inhibitor Unleashes a Cytotoxic Enzyme. Biochemistry. 2009 ;48:5051-5053.
Binder JB, Raines RT. Simple Chemical Transformation of Lignocellulosic Biomass into Furans for Fuels and Chemicals. Journal of the American Chemical Society. 2009 ;131:1979-1985.
Derewenda U, Boczek T, Gorres KL, Yu M, Hung LW, Cooper D, Joachimiak A, Raines RT, Derewenda ZS. Structure and Function of Bacillus subtilis YphP, a Prokaryotic Disulfide Isomerase with a CXC Catalytic Motif. Biochemistry. 2009 ;48:8664-8671.
2010
Shoulders MD, Kotch FW, Choudhary A, Guzei IA, Raines RT. The Aberrance of the 4S Diastereomer of 4-Hydroxyproline. Journal of the American Chemical Society. 2010 ;132:10857-10865.
Kalia J, Raines RT. Advances in Bioconjugation. Current Organic Chemistry. 2010 ;14:138-147.
Rutkoski TJ, Kink JA, Strong LE, Schilling CI, Raines RT. Antitumor Activity of Ribonuclease Multimers Created by Site-Specific Covalent Tethering. Bioconjugate Chemistry. 2010 ;21:1691-1702.
Martin LJ, Raines RT. Carpe Diubiquitin. Angewandte Chemie-International Edition. 2010 ;49:9042-9044.
Chao T-Y, Lavis LD, Raines RT. Cellular Uptake of Ribonuclease A Relies on Anionic Glycans. Biochemistry. 2010 ;49:10666-10673.
Binder JB, Raines RT. Fermentable sugars by chemical hydrolysis of biomass. Proceedings of the National Academy of Sciences of the United States of America. 2010 ;107:4516-4521.
Binder JB, Cefali AV, Blank JJ, Raines RT. Mechanistic insights on the conversion of sugars into 5-hydroxymethylfurfural. Energy & Environmental Science. 2010 ;3:765-771.
Choudhary A, Fry CG, Raines RT. Modulation of an n ->pi* interaction with alpha-fluoro groups. Arkivoc. 2010 :251-262.
Bartlett GJ, Choudhary A, Raines RT, Woolfson DN. n ->pi* interactions in proteins. Nature Chemical Biology. 2010 ;6:615-620.
Jakobsche CE, Choudhary A, Miller SJ, Raines RT. n -> pi(star) Interaction and n)(pi Pauli Repulsion Are Antagonistic for Protein Stability. Journal of the American Chemical Society. 2010 ;132:6651-+.
Krow GR, Liu N, Sender M, Lin G, Centafont R, Sonnet PE, De Brosse C, Ross, Charles W. III, Carroll PJ, Shoulders MD, et al. Oligomers of a 5-Carboxy-methanopyrrolidine beta-Amino Acid. A Search for Order. Organic Letters. 2010 ;12:5438-5441.
Gorres KL, Raines RT. Prolyl 4-hydroxylase. Critical Reviews in Biochemistry and Molecular Biology. 2010 ;45:106-124.
Shoulders MD, Satyshur KA, Forest KT, Raines RT. Stereoelectronic and steric effects in side chains preorganize a protein main chain. Proceedings of the National Academy of Sciences of the United States of America. 2010 ;107:559-564.
Choudhary A, Kamer KJ, Powner MW, Sutherland JD, Raines RT. A Stereoelectronic Effect in Prebiotic Nucleotide Synthesis. ACS Chemical Biology. 2010 ;5:655-657.
Binder JB, Blank JJ, Cefali AV, Raines RT. Synthesis of Furfural from Xylose and Xylan. Chemsuschem. 2010 ;3:1268-1272.
2011
Sundlass NK, Raines RT. Arginine Residues Are More Effective than Lysine Residues in Eliciting the Cellular Uptake of Onconase. Biochemistry. 2011 ;50:10293-10299.
Cuchillo CM, Victoria Nogues M, Raines RT. Bovine Pancreatic Ribonuclease: Fifty Years of the First Enzymatic Reaction Mechanism. Biochemistry. 2011 ;50:7835-7841.
McGrath NA, Raines RT. Chemoselectivity in Chemical Biology: Acyl Transfer Reactions with Sulfur and Selenium. Accounts of Chemical Research. 2011 ;44:752-761.
Chattopadhyay S, Guthrie KM, Teixeira L, Li L, Kiessling LL, Dubielzig RR, Murphy CJ, McAnulty JF, Raines RT. Collagen Mimetic Peptides Enable Cutaneous Wound Assessment and Expedite Healing. Biopolymers. 2011 ;96:427-427.
Caes BR, Raines RT. Conversion of Fructose into 5-(Hydroxymethyl)furfural in Sulfolane. Chemsuschem. 2011 ;4:353-356.
Ma L, Sundlass NK, Raines RT, Cui Q. Disruption and Formation of Surface Salt Bridges Are Coupled to DNA Binding by the Integration Host Factor: A Computational Analysis. Biochemistry. 2011 ;50:266-275.
Choudhary A, Raines RT. An Evaluation of Peptide-Bond Isosteres. Chembiochem. 2011 ;12:1801-1807.
Thiyagarajan N, Smith BD, Raines RT, Acharya RK. Functional and structural analyses of N-acylsulfonamide-linked dinucleoside inhibitors of RNase A. FEBS Journal. 2011 ;278:541-549.
Shoulders MD, Raines RT. Interstrand Dipole-Dipole Interactions Can Stabilize the Collagen Triple Helix. Journal of Biological Chemistry. 2011 ;286:22905-22912.
Chao T-Y, Raines RT. Mechanism of Ribonuclease A Endocytosis: Analogies to Cell-Penetrating Peptides. Biochemistry. 2011 ;50:8374-8382.
Choudhary A, Kamer KJ, Raines RT. An n→π* Interaction in Aspirin: Implications for Structure and Reactivity. Journal of Organic Chemistry. 2011 ;76:7933-7937.
Ellis GA, Hornung ML, Raines RT. Potentiation of ribonuclease cytotoxicity by a poly(amidoamine) dendrimer. Bioorganic & Medicinal Chemistry Letters. 2011 ;21:2756-2758.
Choudhary A, Pua KH, Raines RT. Quantum mechanical origin of the conformational preferences of 4-thiaproline and its S-oxides. Amino Acids. 2011 ;41:181-186.
Watkins RW, Arnold U, Raines RT. Ribonuclease S redux. Chemical Communications. 2011 ;47:973-975.
Levine MN, Raines RT. Sensitive fluorogenic substrate for alkaline phosphatase. Analytical Biochemistry. 2011 ;418:247-252.
Caes BR, Binder JB, Blank JJ, Raines RT. Separable fluorous ionic liquids for the dissolution and saccharification of cellulose. Green Chemistry. 2011 ;13:2719-2722.
Choudhary A, Raines RT. Signature of n ->pi* interactions in alpha-helices. Protein Science. 2011 ;20:1077-1081.
Smith BD, Higgin JJ, Raines RT. Site-specific folate conjugation to a cytotoxic protein. Bioorganic & Medicinal Chemistry Letters. 2011 ;21:5029-5032.
Rutkoski TJ, Kink JA, Strong LE, Raines RT. Site-specific PEGylation endows a mammalian ribonuclease with antitumor activity. Cancer Biology & Therapy. 2011 ;12:208-214.
Lavis LD, Chao T-Y, Raines RT. Synthesis and utility of fluorogenic acetoxymethyl ethers. Chemical Science. 2011 ;2:521-530.
Krow GR, Edupuganti R, Gandla D, Yu F, Sender M, Sonnet PE, Zdilla MJ, DeBrosse C, Cannon KC, Ross, Charles W. III, et al. Synthesis of Conformationally Constrained 5-Fluoro- and 5-Hydroxymethanopyrrolidines. Ring-Puckered Mimics of Gauche- and Anti-3-Fluoro- and 3-Hydroxypyrrolidines. Journal of Organic Chemistry. 2011 ;76:3626-3634.
Pinkas DM, Ding S, Raines RT, Barron AE. Tunable, Post-translational Hydroxylation of Collagen Domains in Escherichia coli. ACS Chemical Biology. 2011 ;6:320-324.

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