All Faculty and Research Staff Publications

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Horng JC, Hawk AJ, Zhao Q, Benedict ES, Burke SD, Raines RT. Macrocyclic scaffold for the collagen triple helix. Organic Letters. 2006 ;8:4735.
Kalia J, Raines RT. Reactivity of intein thioesters: Appending a functional group to a protein. Chembiochem. 2006 ;7:1375.
Shoulders MD, Hodges JA, Raines RT. Reciprocity of steric and stereoelectronic effects in the collagen triple helix. Journal of the American Chemical Society. 2006 ;128:8112.
Johnson RJ, Lin SR, Raines RT. A ribonuclease zymogen activated by the NS3 protease of the hepatitis C virus. FEBS Journal. 2006 ;273:5457.
Kotch FW, Raines RT. Self-assembly of synthetic collagen triple helices. Proceedings of the National Academy of Sciences of the United States of America. 2006 ;103:3028-3033.
Eckenroth B, Harris K, Turanov AA, Gladyshev VN, Raines RT, Hondal RJ. Semisynthesis and characterization of mammalian thioredoxin reductase. Biochemistry. 2006 ;45:5158-5170.
Soellner MB, Tam A, Raines RT. Staudinger ligation of peptides at non-glycyl residues. Journal of Organic Chemistry. 2006 ;71:9824-9830.
Horng JC, Raines RT. Stereoelectronic effects on polyproline conformation. Protein Science. 2006 ;15:74-83.
Kiessling LL, Wedde SG, Raines RT. Symbiosis: Chemical biology at Wisconsin. ACS Chemical Biology. 2006 ;1:481-484.
Fuchs SM, Raines RT. Arginine grafting to endow cell permeability. ACS Chemical Biology. 2007 ;2:167-170.
Kalia J, Raines RT. Catalysis of imido group hydrolysis in a maleimide conjugate. Bioorganic & Medicinal Chemistry Letters. 2007 ;17:6286-6289.
Johnson JR, Chao T-Y, Lavis LD, Raines RT. Cytotoxic ribonucleases: The dichotomy of coulombic forces. Biochemistry. 2007 ;46:10308-10316.
Kalia J, Abbott NL, Raines RT. General method for site-specific protein immobilization by staudinger ligation. Bioconjugate Chemistry. 2007 ;18:1064-1069.
Johnson JR, Lin SR, Raines RT. Genetic selection reveals the role of a buried, conserved polar residue. Protein Science. 2007 ;16:1609-1616.
Horng J-C, Kotch FW, Raines RT. Is glycine a surrogate for a D-amino acid in the collagen triple helix?. Protein Science. 2007 ;16:208-215.
Fuchs SM, Rutkoski TJ, Kung VM, Groeschl RT, Raines RT. Increasing the potency of a cytotoxin with an arginine graft. Protein Engineering Design & Selection. 2007 ;20:505-509.
Johnson JR, McCoy JG, Bingman CA, Phillips, Jr. GN, Raines RT. Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein. Journal of Molecular Biology. 2007 ;368:434-449.
Johnson JR, Lavis LD, Raines RT. Intraspecies regulation of ribonucleolytic activity. Biochemistry. 2007 ;46:13131-13140.
Shoulders MD, Raines RT. Modulating collagen triple helix stability with 4-chloro-, 4-fluoro-, and 4-methylprolines. Biopolymers. 2007 ;88:593-593.
Jewell CM, Fuchs SM, Flessner RM, Raines RT, Lynn DM. Multilayered films fabricated from an oligoarginine-conjugated protein promote efficient surface-mediated protein transduction. Biomacromolecules. 2007 ;8:857-863.
Binder JB, Blank JJ, Raines RT. Olefin metathesis in homogenous aqueous media catalyzed by conventional ruthenium catalysts. Organic Letters. 2007 ;9:4885-4888.
Tam A, Arnold U, Soellner MB, Raines RT. Protein prosthesis: 1,5-disubstituted[1,2,3]triazoles as cis-peptide bond surrogates. Journal of the American Chemical Society. 2007 ;129:12670-+.
Binder JB, Guzei IA, Raines RT. Salicylaldimine ruthenium alkylidene complexes: Metathesis catalysts tuned for protic solvents. Advanced Synthesis & Catalysis. 2007 ;349:395-404.
Lavis LD, Rutkoski TJ, Raines RT. Tuning the pK(a) of fluorescein to optimize binding assays. Analytical Chemistry. 2007 ;79:6775-6782.
Govindaraju T, Bertics PJ, Raines RT, Abbott NL. Using measurements of anchoring energies of liquid crystals on surfaces to quantify proteins captured by immobilized ligands. Journal of the American Chemical Society. 2007 ;129:11223-11231.
Tam A, Soellner MB, Raines RT. Water-soluble phosphinothiols for traceless Staudinger ligation and integration with expressed protein ligation. Journal of the American Chemical Society. 2007 ;129:11421-11430.
Shoulders MD, Guzei IA, Raines RT. 4-chloroprolines: Synthesis, conformational analysis, and effect on the collagen triple helix. Biopolymers. 2008 ;89:443-454.
Lavis LD, Raines RT. Bright ideas for chemical biology. ACS Chemical Biology. 2008 ;3:142-155.
Gorres KL, Edupuganti R, Krow GR, Raines RT. Conformational preferences of substrates for human prolyl 4-hydroxylase. Biochemistry. 2008 ;47:9447-9455.
Turcotte RF, Raines RT. Design and Characterization of an HIV-Specific Ribonuclease Zymogen. AIDS Research and Human Retroviruses. 2008 ;24:1357-1363.
Tam A, Soellner MB, Raines RT. Electronic and steric effects on the rate of the traceless Staudinger ligation. Organic & Biomolecular Chemistry. 2008 ;6:1173-1175.
Rutkoski TJ, Raines RT. Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity. Current Pharmaceutical Biotechnology. 2008 ;9:185-199.
Smith BD, Raines RT. Genetic selection for peptide inhibitors of angiogenin. Protein Engineering Design & Selection. 2008 ;21:289-294.
Yatzeck MM, Lavis LD, Chao TY, Chandran SS, Raines RT. A highly sensitive fluorogenic probe for cytochrome P450 activity in live cells. Bioorganic & Medicinal Chemistry Letters. 2008 ;18:5864-5866.
Kalia J, Raines RT. Hydrolytic stability of hydrazones and oximes. Angewandte Chemie-International Edition. 2008 ;47:7523-7526.
Turcotte RF, Raines RT. Interaction of onconase with the human ribonuclease inhibitor protein. Biochemical and Biophysical Research Communications. 2008 ;377:512-514.
Raines RT. Jeremy R. Knowles (1935-2006). ACS Chemical Biology. 2008 ;3:262-264.
Binder JB, Raines RT. Olefin metathesis for chemical biology. Current Opinion in Chemical Biology. 2008 ;12:767-773.
Wennemers H, Raines RT. Peptides and peptidomimetics as prototypes Editorial overview. Current Opinion in Chemical Biology. 2008 ;12:690-691.
Chorghade MS, Mohapatra DK, Sahoo G, Gurjar MK, Mandlecha MV, Bhoite N, Moghe S, Raines RT. Practical syntheses of 4-fluoroprolines. Journal of Fluorine Chemistry. 2008 ;129:781-784.
Lee EJ, Raines RT. Ribonucleases as novel chemotherapeutics - The ranpirnase example. Biodrugs. 2008 ;22:53-58.
Gottlieb D, Morin SA, Jin S, Raines RT. Self-assembled collagen-like peptide fibers as templates for metallic nanowires. Journal of Materials Chemistry. 2008 ;18:3865-3870.
Kotch FW, Guzei IA, Raines RT. Stabilization of the collagen triple helix by O-methylation of hydroxyproline residues. Journal of the American Chemical Society. 2008 ;130:2952-2953.
Lee EJ, Bae E, Bingman CA, Phillips, Jr. GN, Raines RT. Structural basis for catalysis by onconase. Journal of Molecular Biology. 2008 ;375:165-177.
Levine MN, Lavis LD, Raines RT. Trimethyl lock: A stable chromogenic substrate for esterases. Molecules. 2008 ;13:204-211.