All Faculty and Research Staff Publications

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Aronoff MR, VanVeller B, Raines RT. Detection of Boronic Acids through Excited-State Intramolecular Proton-Transfer Fluorescence. Organic Letters. 2013 ;15:5382-5385.
VanVeller B, Aronoff MR, Raines RT. A divalent protecting group for benzoxaboroles. Rsc Advances. 2013 ;3:21331-21334.
Marshall CJ, Agarwal N, Kalia J, Grosskopf VA, McGrath NA, Abbott NL, Raines RT, Shusta EV. Facile Chemical Functionalization of Proteins through Intein-Linked Yeast Display. Bioconjugate Chemistry. 2013 ;24:1634-1644.
Chao TY, Raines RT. Fluorogenic label to quantify the cytosolic delivery of macromolecules. Molecular Biosystems. 2013 ;9:339-342.
Levine MN, Hoang TT, Raines RT. Fluorogenic Probe for Constitutive Cellular Endocytosis. Chemistry & Biology. 2013 ;20:614-618.
Rutkoski TJ, Kink JA, Strong LE, Raines RT. Human Ribonuclease with a Pendant Poly(Ethylene Glycol) Inhibits Tumor Growth in Mice. Transl Oncol. 2013 ;6:392-397.
Bartlett GJ, Newberry RW, VanVeller B, Raines RT, Woolfson DN. Interplay of Hydrogen Bonds and n ->pi* Interactions in Proteins. Journal of the American Chemical Society. 2013 ;135:18682-18688.
Kamer KJ, Choudhary A, Raines RT. Intimate Interactions with Carbonyl Groups: Dipole-Dipole or n ->pi*?. Journal of Organic Chemistry. 2013 ;78:2099-2103.
Choudhary A, Fry CG, Kamer KJ, Raines RT. An n -> pi* interaction reduces the electrophilicity of the acceptor carbonyl group. Chemical Communications. 2013 ;49:8166-8168.
Newberry RW, VanVeller B, Guzei IA, Raines RT. n ->pi* Interactions of Amides and Thioamides: Implications for Protein Stability. Journal of the American Chemical Society. 2013 ;135:7843-7846.
Newberry RW, Raines RT. n ->pi(star) interactions in poly(lactic acid) suggest a role in protein folding. Chemical Communications. 2013 ;49:7699-7701.
Riccio G, D'Avino C, Raines RT, De Lorenzo C. A novel fully human antitumor ImmunoRNase resistant to the RNase inhibitor. Protein Engineering Design & Selection. 2013 ;26:243-248.
Caes BR, Palte MJ, Raines RT. Organocatalytic conversion of cellulose into a platform chemical. Chemical Science. 2013 ;4:196-199.
Arnold U, Huck BR, Gellman SH, Raines RT. Protein prosthesis: beta-peptides as reverse-turn surrogates. Protein Science. 2013 ;22:274-279.
Guzei IA, Choudhary A, Raines RT. Pyramidalization of a carbonyl C atom in (2S)-N-(selenoacetyl)proline methyl ester. Acta Crystallographica Section E. 2013 ;69:o805-o806.
Caes BR, Van Oosbree TR, Lu FC, Ralph J, Maravelias CT, Raines RT. Simulated Moving Bed Chromatography: Separation and Recovery of Sugars and Ionic Liquid from Biomass Hydrolysates. Chemsuschem. 2013 ;6:2083-2089.
Desai KK, Bingman CA, Phillips GN, Raines RT. Structures of the Noncanonical RNA Ligase RtcB Reveal the Mechanism of Histidine Guanylylation. Biochemistry. 2013 ;52:2518-2525.
Lukesh JC, VanVeller B, Raines RT. Thiols and Selenols as Electron-Relay Catalysts for Disulfide-Bond Reduction. Angewandte Chemie-International Edition. 2013 ;52:12901-12904.
Ellis GA, Palte MJ, Raines RT. Boronate-Mediated Biologic Delivery. Journal of the American Chemical SocietyJournal of the American Chemical Society. 2012 ;134:3631-3634.
Choudhary A, Kamer KJ, Raines RT. A conserved interaction with the chromophore of fluorescent proteins. Protein Science. 2012 ;21:171-177.
Sen SM, Binder JB, Raines RT, Maravelias CT. Conversion of biomass to sugars via ionic liquid hydrolysis: process synthesis and economic evaluation. Biofuels Bioproducts & Biorefining. 2012 ;6:444-452.
McGrath NA, Raines RT. Diazo compounds as highly tunable reactants in 1,3-dipolar cycloaddition reactions with cycloalkynes. Chemical Science. 2012 ;3:3237-3240.
Palte MJ, Raines RT. Interaction of Nucleic Acids with the Glycocalyx. Journal of the American Chemical Society. 2012 ;134:6218-6223.
Chattopadhyay S, Murphy CJ, McAnulty JF, Raines RT. Peptides that anneal to natural collagen in vitro and ex vivo. Organic & Biomolecular Chemistry. 2012 ;10:5892-5897.
Lukesh JC, Palte MJ, Raines RT. A Potent, Versatile Disulfide-Reducing Agent from Aspartic Acid. Journal of the American Chemical Society. 2012 ;134:4057-4059.
Lomax JE, Eller CH, Raines RT. RATIONAL DESIGN AND EVALUATION OF MAMMALIAN RIBONUCLEASE CYTOTOXINS. In: Wittrup KD, Verdine GL Methods in Enzymology. Vol. 502. Methods in Enzymology. San Diego: Elsevier Academic Press Inc; 2012. pp. 273-290.
Ellis GA, McGrath NA, Palte MJ, Raines RT. Ribonuclease-Activated Cancer Prodrug. Acs Medicinal Chemistry Letters. 2012 ;3:268-272.
Palte MJ, Davis AKF, McGrath NA, Spiegel CA, Raines RT. Ribonucleoside 3'-Phosphates as Pro-Moieties for an Orally Administered Drug. Chemmedchem. 2012 ;7:1361-1364.
Krow GR, Shoulders MD, Edupuganti R, Gandla D, Yu F, Sonnet PE, Sender M, Choudhary A, DeBrosse C, Ross CW, et al. Synthesis of 5-Fluoro- and 5-Hydroxymethanoprolines via Lithiation of N-BOC-methanopyrrolidines. Constrained C-gamma-Exo and C-gamma-Endo Flp and Hyp Conformer Mimics. Journal of Organic Chemistry. 2012 ;77:5331-5344.
Levine MN, Raines RT. Trimethyl lock: a trigger for molecular release in chemistry, biology, and pharmacology. Chemical Science. 2012 ;3:2412-2420.
Desai KK, Raines RT. tRNA Ligase Catalyzes the GTP-Dependent Ligation of RNA with 3 '-Phosphate and 5 '-Hydroxyl Termini. Biochemistry. 2012 ;51:1333-1335.
Sundlass NK, Raines RT. Arginine Residues Are More Effective than Lysine Residues in Eliciting the Cellular Uptake of Onconase. Biochemistry. 2011 ;50:10293-10299.
Cuchillo CM, Victoria Nogues M, Raines RT. Bovine Pancreatic Ribonuclease: Fifty Years of the First Enzymatic Reaction Mechanism. Biochemistry. 2011 ;50:7835-7841.
McGrath NA, Raines RT. Chemoselectivity in Chemical Biology: Acyl Transfer Reactions with Sulfur and Selenium. Accounts of Chemical Research. 2011 ;44:752-761.
Chattopadhyay S, Guthrie KM, Teixeira L, Li L, Kiessling LL, Dubielzig RR, Murphy CJ, McAnulty JF, Raines RT. Collagen Mimetic Peptides Enable Cutaneous Wound Assessment and Expedite Healing. Biopolymers. 2011 ;96:427-427.
Caes BR, Raines RT. Conversion of Fructose into 5-(Hydroxymethyl)furfural in Sulfolane. Chemsuschem. 2011 ;4:353-356.
Ma L, Sundlass NK, Raines RT, Cui Q. Disruption and Formation of Surface Salt Bridges Are Coupled to DNA Binding by the Integration Host Factor: A Computational Analysis. Biochemistry. 2011 ;50:266-275.
Choudhary A, Raines RT. An Evaluation of Peptide-Bond Isosteres. Chembiochem. 2011 ;12:1801-1807.
Thiyagarajan N, Smith BD, Raines RT, Acharya RK. Functional and structural analyses of N-acylsulfonamide-linked dinucleoside inhibitors of RNase A. FEBS Journal. 2011 ;278:541-549.
Shoulders MD, Raines RT. Interstrand Dipole-Dipole Interactions Can Stabilize the Collagen Triple Helix. Journal of Biological Chemistry. 2011 ;286:22905-22912.
Chao T-Y, Raines RT. Mechanism of Ribonuclease A Endocytosis: Analogies to Cell-Penetrating Peptides. Biochemistry. 2011 ;50:8374-8382.
Choudhary A, Kamer KJ, Raines RT. An n→π* Interaction in Aspirin: Implications for Structure and Reactivity. Journal of Organic Chemistry. 2011 ;76:7933-7937.
Ellis GA, Hornung ML, Raines RT. Potentiation of ribonuclease cytotoxicity by a poly(amidoamine) dendrimer. Bioorganic & Medicinal Chemistry Letters. 2011 ;21:2756-2758.
Choudhary A, Pua KH, Raines RT. Quantum mechanical origin of the conformational preferences of 4-thiaproline and its S-oxides. Amino Acids. 2011 ;41:181-186.
Watkins RW, Arnold U, Raines RT. Ribonuclease S redux. Chemical Communications. 2011 ;47:973-975.
Levine MN, Raines RT. Sensitive fluorogenic substrate for alkaline phosphatase. Analytical Biochemistry. 2011 ;418:247-252.
Caes BR, Binder JB, Blank JJ, Raines RT. Separable fluorous ionic liquids for the dissolution and saccharification of cellulose. Green Chemistry. 2011 ;13:2719-2722.
Choudhary A, Raines RT. Signature of n ->pi* interactions in alpha-helices. Protein Science. 2011 ;20:1077-1081.
Smith BD, Higgin JJ, Raines RT. Site-specific folate conjugation to a cytotoxic protein. Bioorganic & Medicinal Chemistry Letters. 2011 ;21:5029-5032.
Rutkoski TJ, Kink JA, Strong LE, Raines RT. Site-specific PEGylation endows a mammalian ribonuclease with antitumor activity. Cancer Biology & Therapy. 2011 ;12:208-214.