All Faculty and Research Staff Publications

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Lockett MR, Carlisle JC, Le DV, Smith LM. Acyl Chloride-Modified Amorphous Carbon Substrates for the Attachment of Alcohol-, Thiol-, and Amine-Containing Molecules. Langmuir. 2009 ;25:5120-5126.
Lockett MR, Smith LM. Attaching Molecules to Chlorinated and Brominated Amorphous Carbon Substrates via Grignard Reactions. Langmuir. 2009 ;25:3340-3343.
Chen S, Phillips MF, Cerrina F, Smith LM. Controlling Oligonucleotide Surface Density in Light-Directed DNA Array Fabrication. Langmuir. 2009 ;25:6570-6575.
Lockett MR, Smith LM. Fabrication and Characterization of DNA Arrays Prepared on Carbon-on-Metal Substrates. Analytical Chemistry. 2009 ;81:6429-6437.
Krusemark CJ, Frey BL, Belshaw PJ, Smith LM. Modifying the Charge State Distribution of Proteins in Electrospray Ionization Mass Spectrometry by Chemical Derivatization. Journal of the American Society for Mass Spectrometry. 2009 ;20:1617-1625.
Chen SY, Smith LM. Photopatterned Thiol Surfaces for Biomolecule Immobilization. Langmuir. 2009 ;25:12275-12282.
Mandir JB, Lockett MR, Phillips MF, Allawi HT, Lyamichev VI, Smith LM. Rapid Determination of RNA Accessible Sites by Surface Plasmon Resonance Detection of Hybridization to DNA Arrays. Analytical Chemistry. 2009 ;81:8949-8956.
Jorabchi K, Smith LM. Single Droplet Separations and Surface Partition Coefficient Measurements Using Laser Ablation Mass Spectrometry. Analytical Chemistry. 2009 ;81:9682-9688.
Saracco SA, Hansson M, Scalf M, Walker JM, Smith LM, Vierstra RD. Tandem affinity purification and mass spectrometric analysis of ubiquitylated proteins in Arabidopsis. Plant Journal. 2009 ;59:344-358.
Lockett MR, Shortreed MR, Smith LM. Aldehyde-terminated amorphous carbon substrates for the fabrication of biomolecule arrays. Langmuir. 2008 ;24:9198-9203.
Lockett MR, Weibel SC, Phillips MF, Shortreed MR, Sun B, Corn RM, Hamers RJ, Cerrina F, Smith LM. Carbon-on-metal films for surface plasmon resonance detection of DNA arrays. Journal of the American Chemical Society. 2008 ;130:8611-8613.
Jorabchi K, Westphall MS, Smith LM. Charge assisted laser desorption/ionization mass spectrometry of droplets. Journal of the American Society for Mass Spectrometry. 2008 ;19:833-840.
Smith LM. Is charge reduction in ESI really necessary?. Journal of the American Society for Mass Spectrometry. 2008 ;19:629-631.
Murray JK, Sadowsky JD, Scalf M, Smith LM, Tomita Y, Gellman SH. Exploration of structure - Activity relationships among foldamer ligands for a specific protein binding site via parallel and split-and-mix library synthesis. Journal of Combinatorial Chemistry. 2008 ;10:204-215.
Lee JE, Mirza SP, Didier DN, Scalf M, Olivier M, Greene AS, Smith LM. Identification of Cell Surface Markers to Differentiate Rat Endothelial and Fibroblast Cells Using Lectin Arrays and LC-ESI-MS/MS. Analytical Chemistry. 2008 ;80:8269-8275.
Phillips MF, Lockett MR, Rodesch MJ, Shortreed MR, Cerrina F, Smith LM. In situ oligonucleotide synthesis on carbon materials: stable substrates for microarray fabrication. Nucleic Acids Research. 2008 ;36.
Frey BL, Krusemark CJ, Ledvina AR, Coon JJ, Belshaw PJ, Smith LM. Ion-ion reactions with fixed-charge modified proteins to produce ions in a single, very high charge state. International Journal of Mass Spectrometry. 2008 ;276:136-143.
Westphall MS, Jorabchi K, Smith LM. Mass spectrometry of acoustically levitated droplets. Analytical Chemistry. 2008 ;80:5847-5853.
Zhang X, Scalf M, Westphall MS, Smith LM. Membrane protein separation and analysis by supercritical fluid chromatography-mass spectrometry. Analytical Chemistry. 2008 ;80:2590-2598.
Freed JK, Shortreed MR, Kleefisch CJ, Smith LM, Greene AS. Revealing the role of phosphatidylserine in shear stress-mediated protection in endothelial cells. Endothelium-Journal of Endothelial Cell Research. 2008 ;15:225-230.
Levenstein ME, Berggren WT, Lee JE, Conard KR, Llanas RA, Wagner RJ, Smith LM, Thomson JA. Secreted Proteoglycans Directly Mediate Human Embryonic Stem Cell-Basic Fibroblast Growth Factor 2 Interactions Critical for Proliferation. Stem Cells. 2008 ;26:3099-3107.
Lockett MR, Phillips MF, Jarecki JL, Peelen D, Smith LM. A tetrafluorophenyl activated ester self-assembled monolayer for the immobilization of amine-modified oligonucleotides. Langmuir. 2008 ;24:69-75.
Chen SY, Zheng T, Shortreed MR, Alexander C, Smith LM. Analysis of cell surface carbohydrate expression patterns in normal and tumorigenic human breast cell lines using lectin arrays. Analytical Chemistry. 2007 ;79:5698-5702.
Lee JE, Didier DN, Lockett MR, Scalf M, Greene AS, Olivier M, Smith LM. Characterization of vascular endothelial growth factor receptors on the endothelial cell surface during hypoxia using whole cell binding arrays. Analytical Biochemistry. 2007 ;369:241-247.
Hilger RT, Westphal MS, Smith LM. Controlling charge on levitating drops. Analytical Chemistry. 2007 ;79:6027-6030.
Kim HS, Qin H, Westphall MS, Smith LM, Blick RH. Field emission from a single nanomechanical pillar. Nanotechnology. 2007 ;18.
Zheng T, Yu H, Alexander CM, Beebe DJ, Smith LM. Lectin-modified microchannels for mammalian cell capture and purification. Biomedical Microdevices. 2007 ;9:611-617.
Lockett MR, Shortreed MR, Smith LM. Molecular beacon-style hybridization assay for quantitative analysis of surface invasive cleavage reactions. Analytical Chemistry. 2007 ;79:6031-6036.
Lamos SM, Shortreed MR, Frey BL, Belshaw PJ, Smith LM. Relative quantification of carboxylic acid metabolites by liquid chromatography - Mass spectrometry using isotopic variants of cholamine. Analytical Chemistry. 2007 ;79:5143-5149.
Qin H, Kim HS, Blick RH, Westphall MS, Smith LM. Subthreshold field emission from thin silicon membranes. Applied Physics Letters. 2007 ;91.
Sun B, Colavita PE, Kim H, Lockett M, Marcus MS, Smith LM, Hamers RJ. Covalent Photochemical Functionalization of Amorphous Carbon Thin Films for Integrated Real-Time Biosensing. Langmuir. 2006 ;22:9598-9605.
Zhang X, Scalf M, Berggren TW, Westphall MS, Smith LM. Identification of mammalian cell lines using MALDI-TOF and LC-ESI-MS/MS mass spectrometry. Journal of the American Society for Mass Spectrometry. 2006 ;17:490-499.
Shortreed MR, Lamos SM, Frey BL, Phillips MF, Patel M, Belshaw PJ, Smith LM. Ionizable isotopic labeling reagent for relative quantification of amine metabolites by mass spectrometry. Analytical Chemistry. 2006 ;78:6398-6403.
Lamos SM, Krusemark CJ, McGee CJ, Scalf M, Smith LM, Belshaw PJ. Mixed isotope photoaffinity reagents for identification of small-molecule targets by mass spectrometry. Angewandte Chemie-International Edition. 2006 ;45:4329-4333.
Smith LM. Nanostructures - The manifold faces of DNA. Nature. 2006 ;440:283-284.
Nie B, Shortreed MR, Smith LM. Quantitative detection of individual cleaved DNA molecules on surfaces using gold nanoparticles and scanning electron microscope imaging. Analytical Chemistry. 2006 ;78:1528-1534.
Peelen D, Kodoyianni V, Lee J, Zheng T, Shortreed MR, Smith LM. Specific capture of mammalian cells by cell surface receptor binding to ligand immobilized on gold thin films. Journal of Proteome Research. 2006 ;5:1580-1585.
Rabaglia ME, Gray-Keller MP, Frey BL, Shortreed MR, Smith LM, Attie AD. alpha-Ketoisocaproate-induced hypersecretion of insulin by islets from diabetes-susceptible mice. American Journal of Physiology - Endocrinology & Metabolism. 2005 ;289:E218-E224.
Frey BL, Lin Y, Westphall MS, Smith LM. Controlling gas-phase reactions for efficient charge reduction electrospray mass spectrometry of intact proteins. Journal of the American Society for Mass Spectrometry. 2005 ;16:1876-1887.
Murray JK, Farooqi B, Sadowsky JD, Scalf M, Freund WA, Smith LM, Chen JD, Gellman SH. Efficient synthesis of a beta-peptide combinatorial library with microwave irradiation. Journal of the American Chemical Society. 2005 ;127:13271-13280.
Peelen D, Smith LM. Immobilization of amine-modified oligonucleotides on aldehyde-terminated alkanethiol monolayers on gold. Langmuir. 2005 ;21:266-271.
Zheng T, Peelen D, Smith LM. Lectin arrays for profiling cell surface carbohydrate expression. Journal of the American Chemical Society. 2005 ;127:9982-9983.
Chen Y, Shortreed MR, Olivier M, Smith LM. Parallel single nucleotide polymorphism genotyping by surface invasive cleavage with universal detection. Analytical Chemistry. 2005 ;77:2400-2405.
Nie B, Shortreed MR, Smith LM. Scoring single-nucleotide polymorphisms at the single-molecule level by counting individual DNA cleavage events on surfaces. Analytical Chemistry. 2005 ;77:6594-6600.
Shortreed MR, Chang SB, Hong DG, Phillips M, Campion B, Tulpan DC, Andronescu M, Condon A, Hoos HH, Smith LM. A thermodynamic approach to designing structure-free combinatorial DNA word sets. Nucleic Acids Research. 2005 ;33:4965-4977.
Tulpan D, Andronescu M, Chang SB, Shortreed MR, Condon A, Hoos HH, Smith LM. Thermodynamically based DNA strand design. Nucleic Acids Research. 2005 ;33:4951-4964.