All Department Publications

Found 332 results
Author Title Type [ Year(Asc)]
Filters: Author is Raines, R. T.  [Clear All Filters]
2013
Chao TY, Raines RT. Fluorogenic label to quantify the cytosolic delivery of macromolecules. Molecular Biosystems. 2013;9:339-342.
Riccio G, D'Avino C, Raines RT, De Lorenzo C. A novel fully human antitumor ImmunoRNase resistant to the RNase inhibitor. Protein Engineering Design & Selection. 2013;26:243-248.
Caes BR, Palte MJ, Raines RT. Organocatalytic conversion of cellulose into a platform chemical. Chemical Science. 2013;4:196-199.
Arnold U, Huck BR, Gellman SH, Raines RT. Protein prosthesis: beta-peptides as reverse-turn surrogates. Protein Science. 2013;22:274-279.
2012
Sen SM, Binder JB, Raines RT, Maravelias CT. Conversion of biomass to sugars via ionic liquid hydrolysis: process synthesis and economic evaluation. Biofuels Bioproducts & Biorefining-Biofpr. 2012;6:444-452.
McGrath NA, Raines RT. Diazo compounds as highly tunable reactants in 1,3-dipolar cycloaddition reactions with cycloalkynes. Chemical Science. 2012;3:3237-3240.
Palte MJ, Raines RT. Interaction of Nucleic Acids with the Glycocalyx. Journal of the American Chemical Society. 2012;134:6218-6223.
Chattopadhyay S, Murphy CJ, McAnulty JF, Raines RT. Peptides that anneal to natural collagen in vitro and ex vivo. Organic & Biomolecular Chemistry. 2012;10:5892-5897.
Lukesh JC, Palte MJ, Raines RT. A Potent, Versatile Disulfide-Reducing Agent from Aspartic Acid. Journal of the American Chemical Society. 2012;134:4057-4059.
Lomax JE, Eller CH, Raines RT. RATIONAL DESIGN AND EVALUATION OF MAMMALIAN RIBONUCLEASE CYTOTOXINS. In: Wittrup KD, Verdine GL Vol. 502. San Diego: Elsevier Academic Press Inc; 2012. pp. 273-290.
Ellis GA, McGrath NA, Palte MJ, Raines RT. Ribonuclease-Activated Cancer Prodrug. Acs Medicinal Chemistry Letters. 2012;3:268-272.
Palte MJ, Davis AKF, McGrath NA, Spiegel CA, Raines RT. Ribonucleoside 3'-Phosphates as Pro-Moieties for an Orally Administered Drug. Chemmedchem. 2012;7:1361-1364.
Krow GR, Shoulders MD, Edupuganti R, Gandla D, Yu F, Sonnet PE, Sender M, Choudhary A, DeBrosse C, Ross CW, et al. Synthesis of 5-Fluoro- and 5-Hydroxymethanoprolines via Lithiation of N-BOC-methanopyrrolidines. Constrained C-gamma-Exo and C-gamma-Endo Flp and Hyp Conformer Mimics. Journal of Organic Chemistry. 2012;77:5331-5344.
Levine MN, Raines RT. Trimethyl lock: a trigger for molecular release in chemistry, biology, and pharmacology. Chemical Science. 2012;3:2412-2420.
Desai KK, Raines RT. tRNA Ligase Catalyzes the GTP-Dependent Ligation of RNA with 3 '-Phosphate and 5 '-Hydroxyl Termini. Biochemistry. 2012;51:1333-1335.
2011
Sundlass NK, Raines RT. Arginine Residues Are More Effective than Lysine Residues in Eliciting the Cellular Uptake of Onconase. Biochemistry. 2011;50:10293-10299.
Cuchillo CM, Victoria Nogues M, Raines RT. Bovine Pancreatic Ribonuclease: Fifty Years of the First Enzymatic Reaction Mechanism. Biochemistry. 2011;50:7835-7841.
McGrath NA, Raines RT. Chemoselectivity in Chemical Biology: Acyl Transfer Reactions with Sulfur and Selenium. Accounts of Chemical Research. 2011;44:752-761.
Chattopadhyay S, Guthrie KM, Teixeira L, Li L, Kiessling LL, Dubielzig RR, Murphy CJ, McAnulty JF, Raines RT. Collagen Mimetic Peptides Enable Cutaneous Wound Assessment and Expedite Healing. Biopolymers. 2011;96:427-427.
Caes BR, Raines RT. Conversion of Fructose into 5-(Hydroxymethyl)furfural in Sulfolane. Chemsuschem. 2011;4:353-356.
Ma L, Sundlass NK, Raines RT, Cui Q. Disruption and Formation of Surface Salt Bridges Are Coupled to DNA Binding by the Integration Host Factor: A Computational Analysis. Biochemistry. 2011;50:266-275.
Choudhary A, Raines RT. An Evaluation of Peptide-Bond Isosteres. Chembiochem. 2011;12:1801-1807.
Thiyagarajan N, Smith BD, Raines RT, Acharya RK. Functional and structural analyses of N-acylsulfonamide-linked dinucleoside inhibitors of RNase A. FEBS Journal. 2011;278:541-549.
Shoulders MD, Raines RT. Interstrand Dipole-Dipole Interactions Can Stabilize the Collagen Triple Helix. Journal of Biological Chemistry. 2011;286:22905-22912.
Chao T-Y, Raines RT. Mechanism of Ribonuclease A Endocytosis: Analogies to Cell-Penetrating Peptides. Biochemistry. 2011;50:8374-8382.
Ellis GA, Hornung ML, Raines RT. Potentiation of ribonuclease cytotoxicity by a poly(amidoamine) dendrimer. Bioorganic & Medicinal Chemistry Letters. 2011;21:2756-2758.
Choudhary A, Pua KH, Raines RT. Quantum mechanical origin of the conformational preferences of 4-thiaproline and its S-oxides. Amino Acids. 2011;41:181-186.
Watkins RW, Arnold U, Raines RT. Ribonuclease S redux. Chemical Communications. 2011;47:973-975.
Levine MN, Raines RT. Sensitive fluorogenic substrate for alkaline phosphatase. Analytical Biochemistry. 2011;418:247-252.
Caes BR, Binder JB, Blank JJ, Raines RT. Separable fluorous ionic liquids for the dissolution and saccharification of cellulose. Green Chemistry. 2011;13:2719-2722.
Choudhary A, Raines RT. Signature of n ->pi* interactions in alpha-helices. Protein Science. 2011;20:1077-1081.
Smith BD, Higgin JJ, Raines RT. Site-specific folate conjugation to a cytotoxic protein. Bioorganic & Medicinal Chemistry Letters. 2011;21:5029-5032.
Rutkoski TJ, Kink JA, Strong LE, Raines RT. Site-specific PEGylation endows a mammalian ribonuclease with antitumor activity. Cancer Biology & Therapy. 2011;12:208-214.
Lavis LD, Chao T-Y, Raines RT. Synthesis and utility of fluorogenic acetoxymethyl ethers. Chemical Science. 2011;2:521-530.
Krow GR, Edupuganti R, Gandla D, Yu F, Sender M, Sonnet PE, Zdilla MJ, DeBrosse C, Cannon KC, Ross, Charles W. III, et al. Synthesis of Conformationally Constrained 5-Fluoro- and 5-Hydroxymethanopyrrolidines. Ring-Puckered Mimics of Gauche- and Anti-3-Fluoro- and 3-Hydroxypyrrolidines. Journal of Organic Chemistry. 2011;76:3626-3634.
Pinkas DM, Ding S, Raines RT, Barron AE. Tunable, Post-translational Hydroxylation of Collagen Domains in Escherichia coli. ACS Chemical Biology. 2011;6:320-324.
2010
Shoulders MD, Kotch FW, Choudhary A, Guzei IA, Raines RT. The Aberrance of the 4S Diastereomer of 4-Hydroxyproline. Journal of the American Chemical Society. 2010;132:10857-10865.
Kalia J, Raines RT. Advances in Bioconjugation. Current Organic Chemistry. 2010;14:138-147.
Rutkoski TJ, Kink JA, Strong LE, Schilling CI, Raines RT. Antitumor Activity of Ribonuclease Multimers Created by Site-Specific Covalent Tethering. Bioconjugate Chemistry. 2010;21:1691-1702.
Martin LJ, Raines RT. Carpe Diubiquitin. Angewandte Chemie-International Edition. 2010;49:9042-9044.
Chao T-Y, Lavis LD, Raines RT. Cellular Uptake of Ribonuclease A Relies on Anionic Glycans. Biochemistry. 2010;49:10666-10673.
Binder JB, Raines RT. Fermentable sugars by chemical hydrolysis of biomass. Proceedings of the National Academy of Sciences of the United States of America. 2010;107:4516-4521.
Binder JB, Cefali AV, Blank JJ, Raines RT. Mechanistic insights on the conversion of sugars into 5-hydroxymethylfurfural. Energy & Environmental Science. 2010;3:765-771.
Choudhary A, Fry CG, Raines RT. Modulation of an n ->pi* interaction with alpha-fluoro groups. Arkivoc. 2010:251-262.
Bartlett GJ, Choudhary A, Raines RT, Woolfson DN. n ->pi* interactions in proteins. Nature Chemical Biology. 2010;6:615-620.
Jakobsche CE, Choudhary A, Miller SJ, Raines RT. n -> pi(star) Interaction and n)(pi Pauli Repulsion Are Antagonistic for Protein Stability. Journal of the American Chemical Society. 2010;132:6651-+.
Krow GR, Liu N, Sender M, Lin G, Centafont R, Sonnet PE, DeBrosse C, Ross, Charles W. III, Carroll PJ, Shoulders MD, et al. Oligomers of a 5-Carboxy-methanopyrrolidine beta-Amino Acid. A Search for Order. Organic Letters. 2010;12:5438-5441.
Gorres KL, Raines RT. Prolyl 4-hydroxylase. Critical Reviews in Biochemistry and Molecular Biology. 2010;45:106-124.
Shoulders MD, Satyshur KA, Forest KT, Raines RT. Stereoelectronic and steric effects in side chains preorganize a protein main chain. Proceedings of the National Academy of Sciences of the United States of America. 2010;107:559-564.
Choudhary A, Kamer KJ, Powner MW, Sutherland JD, Raines RT. A Stereoelectronic Effect in Prebiotic Nucleotide Synthesis. ACS Chemical Biology. 2010;5:655-657.

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