All Department Publications

Found 175 results
Author Title Type [ Year(Asc)]
Filters: Author is Kiessling, L. L.  [Clear All Filters]
2012
Wong ML, Guzei IA, Kiessling LL. An Asymmetric Synthesis of L-Pyrrolysine. Organic Letters. 2012;14:1378-1381.
Brown CD, Rusek MS, Kiessling LL. Fluorosugar Chain Termination Agents as Probes of the Sequence Specificity of a Carbohydrate Polymerase. Journal of the American Chemical Society. 2012;134:6552-6555.
Musah S, Morin SA, Wrighton PJ, Zwick DB, Jin S, Kiessling LL. Glycosaminoglycan-binding hydrogels enable mechanical control of human pluripotent stem cell self-renewal. ACS Nano. 2012;6(11):10168-77.
Musah S, Morin SA, Wrighton PJ, Zwick DB, Jin S, Kiessling LL. Glycosaminoglycan-Binding Hydrogels Enable Mechanical Control of Human Pluripotent Stem Cell Self-Renewal. Acs Nano. 2012;6:10168-10177.
Prost LR, Grim JC, Tonelli M, Kiessling LL. Noncarbohydrate Glycomimetics and Glycoprotein Surrogates as DC-SIGN Antagonists and Agonists. ACS Chemical Biology. 2012;7:1603-1608.
May JF, Levengood MR, Splain RA, Brown CD, Kiessling LL. A Processive Carbohydrate Polymerase That Mediates Bifunctional Catalysis Using a Single Active Site. Biochemistry. 2012;51:1148-1159.
Mangold SL, Prost LR, Kiessling LL. Quinoxalinone inhibitors of the lectin DC-SIGN. Chemical Science. 2012;3:772-777.
Kiessling LL. Recasting Biomolecules for Function. ACS Chemical Biology [Internet]. 2012;7:1-2. Available from: http://pubs.acs.org/doi/abs/10.1021/cb300006r
Klim JR, Fowler AJ, Courtney AH, Wrighton PJ, Sheridan RTC, Wong ML, Kiessling LL. Small-Molecule-Modified Surfaces Engage Cells through the alpha(v)beta(3) Integrin. ACS Chemical Biology. 2012;7:518-525.
2010
Kiessling LL, Splain RA. Chemical Approaches to Glycobiology. Annual Review of Biochemistry [Internet]. 2010;79:619-653. Available from: http://www.annualreviews.org/doi/abs/10.1146/annurev.biochem.77.070606.100917
Underbakke ES, Kiessling LL. Classifying chemoreceptors: quantity versus quality. EMBO Journal. 2010;29:3435-3436.
Kiessling LL. Decoding Signals with Chemical Biology. ACS Chemical Biology [Internet]. 2010;5:1-2. Available from: http://pubs.acs.org/doi/abs/10.1021/cb100006u
Klim JR, Li L, Wrighton PJ, Piekarczyk MS, Kiessling LL. A defined glycosaminoglycan-binding substratum for human pluripotent stem cells. Nature Methods. 2010;7:989-U72.
Garber KCA, Wangkanont K, Carlson EE, Kiessling LL. A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN. Chemical Communications. 2010;46:6747-6749.
Derda R, Musah S, Orner BP, Klim JR, Li L, Kiessling LL. High-Throughput Discovery of Synthetic Surfaces That Support Proliferation of Pluripotent Cells. Journal of the American Chemical Society. 2010;132:1289-1295.
Li L, Orner BP, Huang T, Hinck AP, Kiessling LL. Peptide ligands that use a novel binding site to target both TGF-beta receptors. Molecular Biosystems. 2010;6:2392-2402.
Splain RA, Kiessling LL. Synthesis of galactofuranose-based acceptor substrates for the study of the carbohydrate polymerase GlfT2. Bioorganic & Medicinal Chemistry. 2010;18:3753-3759.
Jiarpinitnun C, Kiessling LL. Unexpected Enhancement in Biological Activity of a GPCR Ligand Induced by an Oligoethylene Glycol Substituent. Journal of the American Chemical Society. 2010;132:8844-+.
2009
Lamanna AC, Kiessling LL. Flow Cytometry Reveals that Multivalent Chemoattractants Effect Swarmer Cell Dedifferentiation. ACS Chemical Biology. 2009;4:828-833.
Kolonko EM, Pontrello JK, Mangold SL, Kiessling LL. General Synthetic Route to Cell-Permeable Block Copolymers via ROMP. Journal of the American Chemical Society. 2009;131:7327-7333.
Gruber TD, Borrok MJ, Westler WM, Forest KT, Kiessling LL. Ligand Binding and Substrate Discrimination by UDP-Galactopyranose Mutase. Journal of Molecular Biology. 2009;391:327-340.
Dykhuizen EC, Kiessling LL. Potent Ligands for Prokaryotic UDP-Galactopyranose Mutase That Exploit an Enzyme Subsite. Organic Letters. 2009;11:193-196.
Allen MJ, Wangkanont K, Raines RT, Kiessling LL. ROMP from ROMP: A New Approach to Graft Copolymer Synthesis. Macromolecules. 2009;42:4023-4027.
Courtney AH, Puffer EB, Pontrello JK, Yang ZQ, Kiessling LL. Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation. Proceedings of the National Academy of Sciences of the United States of America. 2009;106:2500-2505.
Borrok MJ, Zhu YM, Forest KT, Kiessling LL. Structure-Based Design of a Periplasmic Binding Protein Antagonist that Prevents Domain Closure. ACS Chemical Biology. 2009;4:447-456.
May JF, Splain RA, Brotschi C, Kiessling LL. A tethering mechanism for length control in a processive carbohydrate polymerization. Proceedings of the National Academy of Sciences of the United States of America. 2009;106:11851-11856.
Gruber TD, Westler WM, Kiessling LL, Forest KT. X-ray Crystallography Reveals a Reduced Substrate Complex of UDP-Galactopyranose Mutase Poised for Covalent Catalysis by Flavin. Biochemistry. 2009;48:9171-9173.
2007
Puffer EB, Pontrello JK, Hollenbeck JJ, Kink JA, Kiessling LL. Activating B cell signaling with defined multivalent ligands. ACS Chemical Biology. 2007;2:252-262.
Owen RM, Carlson CB, Xu J, Mowery P, Fasella E, Kiessling LL. Bifunctional ligands that target cells displaying the alpha(v)beta(3) integrin. Chembiochem. 2007;8:68-82.
Borrok JM, Kiessling LL, Forest KT. Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures. Protein Science. 2007;16:1032-1041.
Derda R, Li L, Orner BP, Lewis RL, Thomson JA, Kiessling LL. Defined substrates for human embryonic stem cell growth identified from surface arrays. ACS Chemical Biology. 2007;2:347-355.
Derda R, Li L, Orner BP, Lewis RL, Thomson JA, Kiessling LL. Defined Substrates for Human Embryonic Stem Cell Growth Identified from Surface Arrays. ACS Chemical Biology [Internet]. 2007;2:347-355. Available from: http://pubs.acs.org/doi/abs/10.1021/cb700032u
McElroy EE, Pontrello JK, Kiessling LL. General strategy for the synthesis of biologically active block copolymers. Polymer Preprints (American Chemical Society, Division of Polymer Chemistry). 2007;48:219-220.
Wangkanont K, Allen MJ, Kiessling LL. Graft co-polymers by ring-opening metathesis polymerization from a main chain containing latent monomers. Polymer Preprints (American Chemical Society, Division of Polymer Chemistry). 2007;48:979.
Kiessling LL, Doudna JA, Johnsson K, Mapp AK, Marletta MA, Seeberger PH, Williamson JR, Wedde SG. A Higher Degree of Difficulty. ACS Chemical Biology [Internet]. 2007;2:197-199. Available from: http://pubs.acs.org/doi/abs/10.1021/cb7000846
Borrok JM, Kiessling LL. Non-carbo hydrate inhibitors of the lectin DC-SIGN. Journal of the American Chemical Society. 2007;129:12780-12785.
Carlson CB, Mowery P, Owen RM, Dykhuizen EC, Kiessling LL. Selective tumor cell targeting using low-affinity, multivalent interactions. ACS Chemical Biology. 2007;2:119-127.
Chad JM, Sarathy KP, Gruber TD, Addala E, Kiessling LL, Sanders DAR. Site-directed mutagenesis of UDP-Galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues. Biochemistry. 2007;46:6723-6732.
Derda R, Wherritt DJ, Kiessling LL. Solid-phase synthesis of alkanethiols for the preparation of self-assembled monolayers. Langmuir. 2007;23:11164-11167.

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