All Department Publications

Found 70 results
Author Title Type [ Year(Asc)]
Filters: Author is Gellman, S. H.  [Clear All Filters]
2013
Chae PS, Rana RR, Gotfryd K, Rasmussen SGF, Kruse AC, Cho KH, Capaldi S, Carlsson E, Kobilka B, Loland CJ, et al. Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study. Chemical Communications. 2013;49:2287-2289.
Arnold U, Huck BR, Gellman SH, Raines RT. Protein prosthesis: beta-peptides as reverse-turn surrogates. Protein Science. 2013;22:274-279.
2012
Woys AM, Almeida AM, Wang L, Chiu CC, McGovern M, de Pablo JJ, Skinner JL, Gellman SH, Zanni MT. Parallel beta-Sheet Vibrational Couplings Revealed by 2D IR Spectroscopy of an Isotopically Labeled Macrocycle: Quantitative Benchmark for the Interpretation of Amyloid and Protein Infrared Spectra. Journal of the American Chemical Society. 2012;134:19118-19128.
Steinkruger JD, Bartlett GJ, Woolfson DN, Gellman SH. Strong Contributions from Vertical Triads to Helix-Partner Preferences in Parallel Coiled Coils. Journal of the American Chemical Society. 2012;134:15652-15655.
2006
Hoerter JM, Otte KM, Gellman SH, Stahl SS. Mechanism of Al-III-catalyzed transamidation of unactivated secondary carboxamides. Journal of the American Chemical Society. 2006;128:5177-5183.
Murray JK, Gellman SH. Microwave-assisted parallel synthesis of a 14-helical beta-peptide library. Journal of Combinatorial ChemistryJournal of Combinatorial Chemistry. 2006;8:58-65.
English EP, Chumanov RS, Gellman SH, Compton T. Rational development of beta-peptide inhibitors of human cytomegalovirus entry. Journal of Biological Chemistry. 2006;281:2661-2667.
2005
Murray JK, Gellman SH. Application of microwave irradiation to the synthesis of 14-helical beta-peptides. Organic LettersOrganic Letters. 2005;7:1517-1520.
Espinosa JF, Syud FA, Gellman SH. An autonomously folding beta-hairpin derived from the human YAP65 WW domain: Attempts to define a minimum ligand-binding motif. BiopolymersBiopolymers. 2005;80:303-311.
Epand RF, Schmitt MA, Gellman SH, Sen A, Auger M, Hughes DW, Epand RM. Bacterial species selective toxicity of two isomeric alpha/beta-peptides: Role of membrane lipids. Molecular Membrane Biology. 2005;22:457-469.
Sadowsky JD, Schmitt MA, Lee HS, Umezawa N, Wang SM, Tomita Y, Gellman SH. Chimeric (alpha/beta plus alpha)-peptide ligands for the BH3-recognition cleft of Bcl-x(L): Critical role of the molecular scaffold in protein surface recognition. Journal of the American Chemical Society. 2005;127:11966-11968.
Chi YG, Gellman SH. Diphenylprolinol methyl ether: A highly enantioselective catalyst for Michael addition of aldehydes to simple enones. Organic LettersOrganic Letters. 2005;7:4253-4256.
Potocky TB, Menon AK, Gellman SH. Effects of conformational stability and geometry of guanidinium display on cell entry by ss-peptides. Journal of the American Chemical Society. 2005;127:3686-3687.
Eldred SE, Pancost MR, Otte KM, Rozema D, Stahl SS, Gellman SH. Effects of side chain configuration and backbone spacing on the gene delivery properties of lysine-derived cationic polymers. Bioconjugate ChemistryBioconjugate Chemistry. 2005;16:694-699.
Murray JK, Farooqi B, Sadowsky JD, Scalf M, Freund WA, Smith LM, Chen JD, Gellman SH. Efficient synthesis of a beta-peptide combinatorial library with microwave irradiation. Journal of the American Chemical Society. 2005;127:13271-13280.
Peelen TJ, Chi YG, Gellman SH. Enantioselective organocatalytic Michael additions of aldehydes to enones with imidazolidinones: Cocatalyst effects and evidence for an enamine intermediate. Journal of the American Chemical Society. 2005;127:11598-11599.
Schmitt MA, Choi SH, Guzei IA, Gellman SH. Residue requirements for helical folding in short alpha/beta-peptides: Crystallographic characterization of the 11-helix in an optimized sequence. Journal of the American Chemical Society. 2005;127:13130-13131.
Huck BR, Gellman SH. Synthesis of 2,2-disubstituted pyrrolidine-4-carboxylic acid derivatives and their incorporation into beta-peptide oligomers. Journal of Organic Chemistry. 2005;70:3353-3362.
Kissounko DA, Guzei IA, Gellman SH, Stahl SS. Titanium(IV)-mediated conversion of carboxamides to amidines and implications for catalytic transamidation. OrganometallicsOrganometallics. 2005;24:5208-5210.
Porter EA, Weisblum B, Gellman SH. Use of parallel synthesis to probe structure-activity relationships among 12-helical beta-peptides: Evidence of a limit on antimicrobial activity. Journal of the American Chemical Society. 2005;127:11516-11529.
2004
Epand RF, Raguse TL, Gellman SH, Epand RM. Antimicrobial 14-helical beta-peptides: Potent bilayer disrupting agents. BiochemistryBiochemistry. 2004;43:9527-9535.
Woll MG, Gellman SH. Backbone thioester exchange: A new approach to evaluating higher order structural stability in polypeptides. Journal of the American Chemical Society. 2004;126:11172-11174.
Gelman MA, Weisblum B, Lynn DM, Gellman SH. Biocidal activity of polystyrenes that are cationic by virtue of protonation. Organic LettersOrganic Letters. 2004;6:557-560.
Langenhan JM, Gellman SH. Effects of alternative side chain pairings and reverse turn sequences on antiparallel sheet structure in beta-peptide hairpins. Organic LettersOrganic Letters. 2004;6:937-940.
Lai JR, Fisk JD, Weisblum B, Gellman SH. Hydrophobic core repacking in a coiled-coil dimer via phage display: Insights into plasticity and specificity at a protein-protein interface. Journal of the American Chemical Society. 2004;126:10514-10515.
Peelen TJ, Chi YG, English EP, Gellman SH. Synthesis of 4,4-disubstituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into 12-helical beta-peptides. Organic LettersOrganic Letters. 2004;6:4411-4414.
Hayen A, Schmitt MA, Ngassa FN, Thomasson KA, Gellman SH. Two helical conformations from a single foldamer backbone: "Split personality" in short alpha/beta-peptides. Angewandte Chemie-International EditionAngewandte Chemie-International Edition. 2004;43:505-510.
Schmitt MA, Weisblum B, Gellman SH. Unexpected relationships between structure and function in alpha,beta-peptides: Antimicrobial foldamers with heterogeneous backbones. Journal of the American Chemical Society. 2004;126:6848-6849.
2003
Park JS, Lee HS, Lai JR, Kim BM, Gellman SH. Accommodation of alpha-substituted residues in the beta-peptide 12-helix: Expanding the range of substitution patterns available to a foldamer scaffold. Journal of the American Chemical Society. 2003;125:8539-8545.
Schinnerl M, Murray JK, Langenhan JM, Gellman SH. Asymmetric synthesis of a new helix-forming beta-amino acid: trans-4-aminopiperidine-3-carboxylic acid. European Journal of Organic ChemistryEuropean Journal of Organic Chemistry. 2003:721-726.
Eldred SE, Stone DA, Gellman SH, Stahl SS. Catalytic transamidation under moderate conditions. Journal of the American Chemical Society. 2003;125:3422-3423.
Potocky TB, Menon AK, Gellman SH. Cytoplasmic and nuclear delivery of a TAT-derived peptide and a beta-peptide after endocytic uptake into HeLa cells. Journal of Biological Chemistry. 2003;278:50188-50194.
Raguse TL, Lai JR, Gellman SH. Environment-independent 14-helix formation in short beta-peptides: Striking a balance between shape control and functional diversity. Journal of the American Chemical Society. 2003;125:5592-5593.
Syud FA, Stanger HE, Mortell HS, Espinosa JF, Fisk JD, Fry CG, Gellman SH. Influence of strand number on antiparallel beta-sheet stability in designed three- and four-stranded beta-sheets. Journal of Molecular Biology. 2003;326:553-568.
Epand RF, Umezawa N, Porter EA, Gellman SH, Epand RM. Interactions of the antimicrobial beta-peptide beta-17 with phospholipid vesicles differ from membrane interactions of magainins. European Journal of Biochemistry. 2003;270:1240-1248.
Bruckner AM, Chakraborty P, Gellman SH, Diederichsen U. Molecular architecture with functionalized beta-peptide helices. Angewandte Chemie-International EditionAngewandte Chemie-International Edition. 2003;42:4395-4399.
Langenhan JM, Guzei IA, Gellman SH. Parallel sheet secondary structure in beta-peptides. Angewandte Chemie-International EditionAngewandte Chemie-International Edition. 2003;42:2402-2405.
Langenhan JM, Gellman SH. Preparation of protected syn-alpha,beta-dialkyl beta-amino acids that contain polar side chain functionality. Journal of Organic Chemistry. 2003;68:6440-6443.
Lai JR, Gellman SH. Reinvestigation of the proposed folding and self-association of the Neuropeptide Head Activator. Protein ScienceProtein Science. 2003;12:560-566.
Gelman MA, Richter S, Cao H, Umezawa N, Gellman SH, Rana TM. Selective binding of TAR RNA by a tat-derived beta-peptide. Organic LettersOrganic Letters. 2003;5:3563-3565.
Bruckner AM, Garcia M, Marsh A, Gellman SH, Diederichsen U. Synthesis of novel nucleo-beta-amino acids and nucleobase-functionalized beta-peptides. European Journal of Organic ChemistryEuropean Journal of Organic Chemistry. 2003:3555-3561.
2002
Espinosa JF, Syud FA, Gellman SH. Analysis of the factors that stabilize a designed two-stranded antiparallel beta-sheet. Protein ScienceProtein Science. 2002;11:1492-1505.
Lai JR, Huck BR, Weisblum B, Gellman SH. Design of non-cysteine-containing antimicrobial beta-hairpins: Structure-activity relationship studies with linear protegrin-1 analogues. BiochemistryBiochemistry. 2002;41:12835-12842.
Lee HS, Park JS, Kim BM, Gellman SH. Efficient synthesis of enantionterically pure beta(2)-amino acids via chiral isoxazolidinones. Journal of Organic Chemistry. 2002;68:1575-1578.
Raguse TL, Lai JR, Gellman SH. Evidence that the beta-peptide 14-Helix is Stabilized by beta(3)-residues with side-chain branching adjacent to the beta-carbon atom. Helvetica Chimica ActaHelvetica Chimica Acta. 2002;85:4154-4164.
Knight SMG, Umezawa N, Lee HS, Gellman SH, Kay BK. A fluorescence polarization assay for the identification of inhibitors of the p53-DM2 protein-protein interaction. Analytical BiochemistryAnalytical Biochemistry. 2002;300:230-236.
Porter EA, Weisblum B, Gellman SH. Mimicry of host-defense peptides by unnatural oligomers: Antimicrobial beta-peptides. Journal of the American Chemical Society. 2002;124:7324-7330.
Gellman SH, Woolfson DN. Mini-proteins Trp the light fantastic. Nature Structural BiologyNature Structural Biology. 2002;9:408-410.
Gellman SH, Raines RT. Model systems - This year's model - Editorial overview. Current Opinion in Chemical BiologyCurrent Opinion in Chemical Biology. 2002;6:727-728.
Arnold U, Hinderaker MP, Nilsson BL, Huck BR, Gellman SH, Raines RT. Protein prosthesis: A semisynthetic enzyme with a beta-peptide reverse turn. Journal of the American Chemical Society. 2002;124:8522-8523.

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