All Faculty and Research Staff Publications

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Jaskula-Sztul R, Chen GJ, Dammalapati A, Harrison A, Tang WP, Gong S, Chen H. AB3-loaded and tumor-targeted unimolecular micelles for medullary thyroid cancer treatment. Journal of Materials Chemistry B. 2017 ;5:151-159.
Xiao GZ, Cintron-Rosado GA, Glazier DA, Xi BM, Liu C, Liu P, Tang WP. Catalytic Site-Selective Acylation of Carbohydrates Directed by Cation-n Interaction. Journal of the American Chemical Society. 2017 ;139:4346-4349.
Wang HY, Simmons CJ, Zhang Y, Smits AM, Balzer PG, Wang SJ, Tang WP. Chiral Catalyst-Directed Dynamic Kinetic Diastereoselective Acylation of Anomeric Hydroxyl Groups and a Controlled Reduction of the Glycosyl Ester Products. Organic Letters. 2017 ;19:508-511.
Song WZ, Wang SJ, Tang WP. De Novo Synthesis of Mono- and Oligosaccharides via Dihydropyran Intermediates. Chemistry-an Asian Journal. 2017 ;12:1027-1042.
Yang Z, Zhu Z, Luo R, Qiu X, Liu J-tian, Yang J-K, Tang WP. Iridium-catalyzed highly efficient chemoselective reduction of aldehydes in water using formic acid as the hydrogen source. Green Chemistry. 2017 ;19:3296-3301.
Yang ZH, Zhu ZP, Luo RS, Qiu X, Liu JT, Yang JK, Tang WP. Iridium-catalyzed highly efficient chemoselective reduction of aldehydes in water using formic acid as the hydrogen source. Green Chemistry. 2017 ;19:3296-3301.
Chen GJ, Jaskula-Sztul R, Esquibel CR, Lou I, Zheng QF, Dammalapati A, Harrison A, Eliceiri KW, Tang WP, Chen H, et al. Neuroendocrine Tumor-Targeted Upconversion Nanoparticle-Based Micelles for Simultaneous NIR-Controlled Combination Chemotherapy and Photodynamic Therapy, and Fluorescence Imaging. Advanced Functional Materials. 2017 ;27.
Liu JT, Simmons CJ, Xie HB, Yang F, Zhao XL, Tang Y, Tang WP. Synthesis of Highly Substituted Benzofuran-containing Natural Products via Rh-catalyzed Carbonylative Benzannulation. Advanced Synthesis & Catalysis. 2017 ;359:693-697.
Song WZ, Blaszczyk SA, Liu JT, Wang SJ, Tang WP. Transition metal mediated carbonylative benzannulations. Organic & Biomolecular Chemistry. 2017 ;15:7490-7504.
Liu RS, Wang JH, Tang WP, Fang H. Design and synthesis of a new generation of substituted purine hydroxamate analogs as histone deacetylase inhibitors. Bioorganic & Medicinal Chemistry. 2016 ;24:1446-1454.
Hideshima T, Qi J, Paranal RM, Tang WP, Greenberg E, West N, Colling ME, Estiu G, Mazitschek R, Perry JA, et al. Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma. Proceedings of the National Academy of Sciences of the United States of America. 2016 ;113:13162-13167.
Song WZ, Lynch JC, Shu XZ, Tang WP. Rhodium-Catalyzed 5+2 Cycloaddition of 3-Acyloxy-1,4-enyne with Alkene or Allene. Advanced Synthesis & Catalysis. 2016 ;358:2007-2011.
Li XX, Song WZ, Ke XN, Xu XF, Liu P, Houk KN, Zhao XL, Tang WP. Rhodium-Catalyzed Intramolecular 5+2 Cycloaddition of Inverted 3-Acyloxy-1,4-enyne and Alkyne: Experimental and Theoretical Studies. Chemistry-A European Journal. 2016 ;22:7079-7083.
Li XX, Xie HB, Fu XN, Liu JT, Wang HY, Xi BM, Liu P, Xu XF, Tang WP. Rhodium(I)-Catalyzed Benzannulation of Heteroaryl Propargylic Esters: Synthesis of Indoles and Related Heterocycles. Chemistry-A European Journal. 2016 ;22:10410-10414.
Song WZ, Li XX, Yang K, Zhao XL, Glazier DA, Xi BM, Tang WP. Synthesis of Carbazoles and Carbazole-Containing Heterocycles via Rhodium-Catalyzed Tandem Carbonylative Benzannulations. Journal of Organic Chemistry. 2016 ;81:2930-2942.
Liu JT, Do TJ, Simmons CJ, Lynch JC, Gu W, Ma ZX, Xu W, Tang WP. Total synthesis of diptoindonesin G and its analogues as selective modulators of estrogen receptors. Organic & Biomolecular Chemistry. 2016 ;14:8927-8930.
Wang HY, Yang K, Yin D, Liu C, Glazier DA, Tang WP. Chiral Catalyst-Directed Dynamic Kinetic Diastereoselective Acylation of Lactols for De Novo Synthesis of Carbohydrate. Organic Letters. 2015 ;17:5272-5275.
Wang L, Hou XB, Fu HS, Pan XL, Xu WF, Tang WP, Fang H. Design, synthesis and preliminary bioactivity evaluations of substituted quinoline hydroxamic acid derivatives as novel histone deacetylase (HDAC) inhibitors. Bioorganic & Medicinal Chemistry. 2015 ;23:4364-4374.
Song WZ, Zhao Y, Lynch JC, Kim H, Tang WP. Divergent de novo synthesis of all eight stereoisomers of 2,3,6-trideoxyhexopyranosides and their oligomers. Chemical Communications. 2015 ;51:17475-17478.
Li XX, Li H, Song WZ, Tseng PS, Liu LY, Guzei IA, Tang WP. Divergent Reactivity of Rhodium(I) Carbenes Derived from Indole Annulations. Angewandte Chemie-International Edition. 2015 ;53:12905-12908.
Wang HY, Yang K, Bennett SR, Guo SR, Tang WP. Iridium-Catalyzed Dynamic Kinetic Isomerization: Expedient Synthesis of Carbohydrates from Achmatowicz Rearrangement Products. Angewandte Chemie-International Edition. 2015 ;54:8756-8759.
Ke XN, Schienebeck CM, Zhou CC, Xu XF, Tang WP. Mechanism and reactivity of rhodium-catalyzed intermolecular 5+1 cycloaddition of 3-acyloxy-1,4-enyne (ACE) and CO: A computational study. Chinese Chemical Letters. 2015 ;26:730-734.
Schienebeck CM, Song WZ, Smits AM, Tang WP. Rhodium-Catalyzed Intermolecular 5+1 and 5+2 Cycloadditions Using 1,4-Enynes with an Electron-Donating Ester on the 3-Position. Synthesis-Stuttgart. 2015 ;47:1076-1084.
Shu XZ, Schienebeck CM, Li XX, Zhou X, Song WZ, Chen LQ, Guzei IA, Tang WP. Rhodium-Catalyzed Stereoselective Intramolecular 5+2 Cycloaddition of 3-Acyloxy 1,4-Enyne and Alkene. Organic Letters. 2015 ;17:5128-5131.
Song WZ, Xi BM, Yang K, Tang WP. Synthesis of substituted tropones by sequential Rh-catalyzed 5+2 cycloaddition and elimination. Tetrahedron. 2015 ;71:5979-5984.
Jaskula-Sztul R, Eide J, Tesfazghi S, Dammalapati A, Harrison AD, Yu XM, Scheinebeck C, Winston-McPherson G, Kupcho KR, Robers MB, et al. Tumor-Suppressor Role of Notch3 in Medullary Thyroid Carcinoma Revealed by Genetic and Pharmacological Induction. Molecular Cancer Therapeutics. 2015 ;14:499-512.
Schienebeck CM, Li XX, Shu XZ, Tang WP. 3-Acyloxy-1,4-enyne: A new five-carbon synthon for rhodium-catalyzed 5+2 cycloadditions. Pure and Applied Chemistry. 2014 ;86:409-417.
Zheng SQ, Schienebeck CM, Zhang W, Wang HY, Tang WP. Cinchona Alkaloids as Organocatalysts in Enantioselective Halofunctionalization of Alkenes and Alkynes. Asian Journal of Organic Chemistry. 2014 ;3:366-376.
Li H, Li XX, Wang HY, Winston-McPherson GN, Geng HMJ, Guzei IA, Tang WP. Copper-catalyzed tandem annulation/arylation for the synthesis of diindolylmethanes from propargylic alcohols. Chemical Communications. 2014 ;50:12293-12296.
Han LQ, Wang L, Hou XB, Fu HS, Song WG, Tang WP, Fang H. Design, synthesis and preliminary bioactivity studies of 1,2-dihydrobenzo d isothiazol-3-one-1,1-dioxide hydroxamic acid derivatives as novel histone deacetylase inhibitors. Bioorganic & Medicinal Chemistry. 2014 ;22:1529-1538.
Wang JH, Sun FE, Han LQ, Hou XB, Pan XL, Liu RS, Tang WP, Fang H. Design, synthesis, and preliminary bioactivity studies of substituted purine hydroxamic acid derivatives as novel histone deacetylase (HDAC) inhibitors. Medchemcomm. 2014 ;5:1887-1891.
Guan P, Wang L, Hou XB, Wan YC, Xu WF, Tang WP, Fang H. Improved antiproliferative activity of 1,3,4-thiadiazole-containing histone deacetylase (HDAC) inhibitors by introduction of the heteroaromatic surface recognition motif. Bioorganic & Medicinal Chemistry. 2014 ;22:5766-5775.
Wang HY, Zhang W, Schienebeck CM, Bennett SR, Tang WP. Intermolecular bromoesterification of conjugated enynes: an efficient synthesis of bromoallenes. Organic Chemistry Frontiers. 2014 ;1:386-390.
Winston-McPherson GN, Shu DX, Tang WP. Synthesis and biological evaluation of 2,3 '-diindolylmethanes as agonists of aryl hydrocarbon receptor. Bioorganic & Medicinal Chemistry Letters. 2014 ;24:4023-4025.
Liu N, Song WZ, Schienebeck CM, Zhang M, Tang WP. Synthesis of naturally occurring tropones and tropolones. Tetrahedron. 2014 ;70:9281-9305.
Fass DM, Reis SA, Ghosh B, Hennig KM, Joseph NF, Zhao WN, Nieland TJF, Guan JS, Kuhnle CEG, Tang WP, et al. Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity. Neuropharmacology. 2013 ;64:81-96.
Schienebeck CM, Robichaux PJ, Li XX, Chen LQ, Tang WP. Effect of ester on rhodium-catalyzed intermolecular 5+2 cycloaddition of 3-acyloxy-1,4-enynes and alkynes. Chemical Communications. 2013 ;49:2616-2618.
Zheng J, Xu CM, Guo J, Wei Y, Ge HJ, Li XC, Zhang CL, Jiang HJ, Pan L, Tang WP, et al. Effective Noninvasive Zygosity Determination by Maternal Plasma Target Region Sequencing. Plos One. 2013 ;8.
Zhang W, Liu N, Schienebeck CM, Zhou X, , Guzei IA, Tang WP. Enantioselective intermolecular bromoesterification of allylic sulfonamides. Chemical Science. 2013 ;4:2652-2656.
Liu RH, Winston-McPherson GN, Yang ZY, Zhou X, Song WZ, Guzei IA, Xu XF, Tang WP. Generation of Rhodium(I) Carbenes from Ynamides and Their Reactions with Alkynes and Alkenes. Journal of the American Chemical Society. 2013 ;135:8201-8204.
Shu DX, Winston-McPherson GN, Song WZ, Tang WP. Platinum-Catalyzed Tandem Indole Annulation/Arylation for the Synthesis of Diindolylmethanes and Indolo 3,2-b carbazoles. Organic Letters. 2013 ;15:4162-4165.
Xu XF, Liu P, Shu XZ, Tang WP, Houk KN. Rh-Catalyzed (5+2) Cycloadditions of 3-Acyloxy-1,4-enynes and Alkynes: Computational Study of Mechanism, Reactivity, and Regioselectivity. Journal of the American Chemical Society. 2013 ;135:9271-9274.
Shu DX, Song WZ, Li XX, Tang WP. Rhodium- and Platinum-Catalyzed 4+3 Cycloaddition with Concomitant Indole Annulation: Synthesis of Cyclohepta b indoles. Angewandte Chemie-International Edition. 2013 ;52:3237-3240.
Xu HD, Zhang RW, Li XX, Huang SY, Tang WP, Hu WH. Rhodium-Catalyzed Chemo- and Regioselective Cross-Dimerization of Two Terminal Alkynes. Organic Letters. 2013 ;15:840-843.
Li XX, Song WZ, Tang WP. Rhodium-Catalyzed Tandem Annulation and (5+1) Cycloaddition: 3-Hydroxy-1,4-enyne as the 5-Carbon Component. Journal of the American Chemical Society. 2013 ;135:16797-16800.
Liu RH, Zhang M, Winston-McPherson G, Tang WP. Ring expansion of alkynyl cyclopropanes to highly substituted cyclobutenes via a N-sulfonyl-1,2,3-triazole intermediate. Chemical Communications. 2013 ;49:4376-4378.
Liu N, Wang HY, Zhang W, Jia ZH, Guzei IA, Xu HD, Tang WP. Stereoselective Halocyclization of Alkenes With N-Acyl Hemiaminal Nucleophiles. Chirality. 2013 ;25:805-809.
Zhang M, Liu N, Tang WP. Stereoselective Total Synthesis of Hainanolidol and Harringtonolide via Oxidopyrylium-Based 5+2 Cycloaddition. Journal of the American Chemical Society. 2013 ;135:12434-12438.
Jarecki BW, Zheng SQ, Zhang LL, Li XX, Zhou X, Cui Q, Tang WP, Chanda B. Tethered Spectroscopic Probes Estimate Dynamic Distances with Subnanometer Resolution in Voltage-Dependent Potassium Channels. Biophysical Journal. 2013 ;105:2724-2732.
Shu XZ, Schienebeck CM, Song WZ, Guzei IA, Tang WP. Transfer of Chirality in the Rhodium-Catalyzed Intramolecular 5+2 Cycloaddition of 3-Acyloxy-1,4-enynes (ACEs) and Alkynes: Synthesis of Enantioenriched Bicyclo 5.3.0 decatrienes. Angewandte Chemie-International Edition. 2013 ;52:13601-13605.