All Faculty and Research Staff Publications

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2020
Yang K, Wu H, Zhang ZR, Leisten ED, Nie XQ, Liu BK, Wen Z, Zhang J, Cunningham MD, Tang WP. Development of Selective Histone Deacetylase 6 (HDAC6) Degraders Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. Acs Medicinal Chemistry Letters. 2020 ;11:575-581.
Luo NH, Liao JH, Ouyang L, Wen HL, Zhong YH, Liu JT, Tang WP, Luo RS. Highly Selective Hydroxylation and Alkoxylation of Silanes: One-Pot Silane Oxidation and Reduction of Aldehydes/Ketones. Organometallics. 2020 ;39:165-171.
Klein MA, Liu C, Kuznetsov VI, Feltenberger JB, Tang WP, Denu JM. Mechanism of activation for the sirtuin 6 protein deacylase. Journal of Biological Chemistry. 2020 ;295:1385-1399.
Blaszczyk SA, Glazier DA, Tang WP. Rhodium-Catalyzed (5+2) and (5+1) Cycloadditions Using 1,4-Enynes as Five-Carbon Building Blocks. Accounts of Chemical Research. 2020 ;53:231-243.
Wu H, Liu BK, Yang K, Winston-McPherson GN, Leisten ED, Vezina CM, Ricke WA, Peterson RE, Tang WP. Synthesis and biological evaluation of FICZ analogues as agonists of aryl hydrocarbon receptor. Bioorganic & Medicinal Chemistry Letters. 2020 ;30.
Wen P, Simmons CJ, Ma ZX, Blaszczyk SA, Balzer PG, Ye WJ, Duan XY, Wang HY, Yin D, Stevens CM, et al. Synthesis of Glycosyl Chlorides and Bromides by Chelation Assisted Activation of Picolinic Esters under Mild Neutral Conditions. Organic Letters. 2020 ;22:1495-1498.
Liu JT, Ye WJ, Wang SJ, Zheng JR, Tang WP, Li XX. Synthesis of Lactams via Ir-Catalyzed C-H Amidation Involving Ir-Nitrene Intermediates. Journal of Organic Chemistry. 2020 ;85:4430-4440.
2019
Wu H, Yang K, Zhang ZR, Leisten ED, Li ZY, Xie HB, Liu J, Smith KA, Noyakova Z, Barinka C, et al. Development of Multifunctional Histone Deacetylase 6 Degraders with Potent Antimyeloma Activity. Journal of Medicinal Chemistry. 2019 ;62:7042-7057.
Wang B, Wu SZ, Liu J, Yang K, Xie HB, Tang WP. Development of selective small molecule MDM2 degraders based on nutlin. European Journal of Medicinal Chemistry. 2019 ;176:476-491.
Winston-McPherson GN, Xie HB, Yang K, Li XX, Shu DX, Tang WP. Discovery of 2,3 '-diindolylmethanes as a novel class of PCSK9 modulators. Bioorganic & Medicinal Chemistry Letters. 2019 ;29:2345-2348.
Cui YS, Yang K, Tabang DN, Huang JF, Tang WP, Li LJ. Finding the Sweet Spot in ERLIC Mobile Phase for Simultaneous Enrichment of N-Glyco and Phosphopeptides. Journal of the American Society for Mass Spectrometry. 2019 ;30:2491-2501.
Zhao CG, Ye ZQ, Ma ZX, Wildman SA, Blaszczyk SA, Hu LH, Guizei IA, Tang WP. A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings. Nature Communications. 2019 ;10.
Luo NH, Liao JH, Ouyang L, Wen HL, Liu JT, Tang WP, Luo RS. Highly pH-Dependent Chemoselective Transfer Hydrogenation of alpha,beta-Unsaturated Aldehydes in Water. Organometallics. 2019 ;38:3025-3031.
Zhao CG, Glazier DA, Yang DS, Yin D, Guzei IA, Aristov MM, Liu P, Tang WP. Intermolecular Regio- and Stereoselective Hetero- 5+2 Cycloaddition of Oxidopyrylium Ylides and Cyclic Imines. Angewandte Chemie-International Edition. 2019 ;58:887-891.
Li JD, Tang WP, Ren DM, Xu JX, Yang ZH. Iridium-catalysed highly selective reduction-elimination of steroidal 4-en-3-ones to 3,5-dienes in water. Green Chemistry. 2019 ;21:2088-2094.
Blaszczyk SA, Homan TC, Tang WP. Recent advances in site-selective functionalization of carbohydrates mediated by organocatalysts. Carbohydrate Research. 2019 ;471:64-77.
Blaszczyk SA, Xiao GZ, Wen P, Hao H, Wu J, Wang B, Carattino F, Li ZY, Glazier DA, McCarty BJ, et al. S-Adamantyl Group Directed Site-Selective Acylation: Applications in Streamlined Assembly of Oligosaccharides. Angewandte Chemie-International Edition. 2019 ;58:9542-9546.
Wu JC, Li XL, Qi XT, Duan XY, Cracraft WL, Guzei IA, Liu P, Tang WP. Site-Selective and Stereoselective O-Alkylation of Glycosides by Rh(II)-Catalyzed Carbenoid Insertion. Journal of the American Chemical Society. 2019 ;141:19902-19910.
Sehgal PD, Bauman TM, Nicholson TM, Vellky JE, Ricke EA, Tang WP, Xu W, Huang W, Ricke WA. Tissue-specific quantification and localization of androgen and estrogen receptors in prostate cancer. Human Pathology. 2019 ;89:99-108.
2017
Jaskula-Sztul R, Chen GJ, Dammalapati A, Harrison A, Tang WP, Gong S, Chen H. AB3-loaded and tumor-targeted unimolecular micelles for medullary thyroid cancer treatment. Journal of Materials Chemistry B. 2017 ;5:151-159.
Xiao GZ, Cintron-Rosado GA, Glazier DA, Xi BM, Liu C, Liu P, Tang WP. Catalytic Site-Selective Acylation of Carbohydrates Directed by Cation-n Interaction. Journal of the American Chemical Society. 2017 ;139:4346-4349.
Wang HY, Simmons CJ, Zhang Y, Smits AM, Balzer PG, Wang SJ, Tang WP. Chiral Catalyst-Directed Dynamic Kinetic Diastereoselective Acylation of Anomeric Hydroxyl Groups and a Controlled Reduction of the Glycosyl Ester Products. Organic Letters. 2017 ;19:508-511.
Song WZ, Wang SJ, Tang WP. De Novo Synthesis of Mono- and Oligosaccharides via Dihydropyran Intermediates. Chemistry-an Asian Journal. 2017 ;12:1027-1042.
Yang ZH, Luo RS, Zhu ZP, Yang XR, Tang WP. Harnessing the Reactivity of Iridium Hydrides by Air: Iridium-Catalyzed Oxidation of Aldehydes to Acids in Water. Organometallics. 2017 ;36:4095-4098.
Yang ZH, Zhu ZP, Luo RS, Qiu X, Liu JT, Yang JK, Tang WP. Iridium-catalyzed highly efficient chemoselective reduction of aldehydes in water using formic acid as the hydrogen source. Green Chemistry. 2017 ;19:3296-3301.
Wang HY, Simmons CJ, Blaszczyk SA, Balzer PG, Luo RS, Duan XY, Tang WP. Isoquinoline-1-Carboxylate as a Traceless Leaving Group for Chelation-Assisted Glycosylation under Mild and Neutral Reaction Conditions. Angewandte Chemie-International Edition. 2017 ;56:15698-15702.
Chen GJ, Jaskula-Sztul R, Esquibel CR, Lou I, Zheng QF, Dammalapati A, Harrison A, Eliceiri KW, Tang WP, Chen H, et al. Neuroendocrine Tumor-Targeted Upconversion Nanoparticle-Based Micelles for Simultaneous NIR-Controlled Combination Chemotherapy and Photodynamic Therapy, and Fluorescence Imaging. Advanced Functional Materials. 2017 ;27:1604671.
Liu JT, Simmons CJ, Xie HB, Yang F, Zhao XL, Tang Y, Tang WP. Synthesis of Highly Substituted Benzofuran-containing Natural Products via Rh-catalyzed Carbonylative Benzannulation. Advanced Synthesis & Catalysis. 2017 ;359:693-697.
Song WZ, Blaszczyk SA, Liu JT, Wang SJ, Tang WP. Transition metal mediated carbonylative benzannulations. Organic & Biomolecular Chemistry. 2017 ;15:7490-7504.
2016
Liu RS, Wang JH, Tang WP, Fang H. Design and synthesis of a new generation of substituted purine hydroxamate analogs as histone deacetylase inhibitors. Bioorganic & Medicinal Chemistry. 2016 ;24:1446-1454.
Hideshima T, Qi J, Paranal RM, Tang WP, Greenberg E, West N, Colling ME, Estiu G, Mazitschek R, Perry JA, et al. Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma. Proceedings of the National Academy of Sciences of the United States of America. 2016 ;113:13162-13167.
Song WZ, Lynch JC, Shu XZ, Tang WP. Rhodium-Catalyzed 5+2 Cycloaddition of 3-Acyloxy-1,4-enyne with Alkene or Allene. Advanced Synthesis & Catalysis. 2016 ;358:2007-2011.
Li XX, Song WZ, Ke XN, Xu XF, Liu P, Houk KN, Zhao XL, Tang WP. Rhodium-Catalyzed Intramolecular 5+2 Cycloaddition of Inverted 3-Acyloxy-1,4-enyne and Alkyne: Experimental and Theoretical Studies. Chemistry-A European Journal. 2016 ;22:7079-7083.
Li XX, Xie HB, Fu XN, Liu JT, Wang HY, Xi BM, Liu P, Xu XF, Tang WP. Rhodium(I)-Catalyzed Benzannulation of Heteroaryl Propargylic Esters: Synthesis of Indoles and Related Heterocycles. Chemistry-A European Journal. 2016 ;22:10410-10414.
Song WZ, Li XX, Yang K, Zhao XL, Glazier DA, Xi BM, Tang WP. Synthesis of Carbazoles and Carbazole-Containing Heterocycles via Rhodium-Catalyzed Tandem Carbonylative Benzannulations. Journal of Organic Chemistry. 2016 ;81:2930-2942.
Liu JT, Do TJ, Simmons CJ, Lynch JC, Gu W, Ma ZX, Xu W, Tang WP. Total synthesis of diptoindonesin G and its analogues as selective modulators of estrogen receptors. Organic & Biomolecular Chemistry. 2016 ;14:8927-8930.
2015
Wang HY, Yang K, Yin D, Liu C, Glazier DA, Tang WP. Chiral Catalyst-Directed Dynamic Kinetic Diastereoselective Acylation of Lactols for De Novo Synthesis of Carbohydrate. Organic Letters. 2015 ;17:5272-5275.
Wang L, Hou XB, Fu HS, Pan XL, Xu WF, Tang WP, Fang H. Design, synthesis and preliminary bioactivity evaluations of substituted quinoline hydroxamic acid derivatives as novel histone deacetylase (HDAC) inhibitors. Bioorganic & Medicinal Chemistry. 2015 ;23:4364-4374.
Song WZ, Zhao Y, Lynch JC, Kim H, Tang WP. Divergent de novo synthesis of all eight stereoisomers of 2,3,6-trideoxyhexopyranosides and their oligomers. Chemical Communications. 2015 ;51:17475-17478.
Li XX, Li H, Song WZ, Tseng PS, Liu LY, Guzei IA, Tang WP. Divergent Reactivity of Rhodium(I) Carbenes Derived from Indole Annulations. Angewandte Chemie-International Edition. 2015 ;53:12905-12908.
Wang HY, Yang K, Bennett SR, Guo SR, Tang WP. Iridium-Catalyzed Dynamic Kinetic Isomerization: Expedient Synthesis of Carbohydrates from Achmatowicz Rearrangement Products. Angewandte Chemie-International Edition. 2015 ;54:8756-8759.
Ke XN, Schienebeck CM, Zhou CC, Xu XF, Tang WP. Mechanism and reactivity of rhodium-catalyzed intermolecular 5+1 cycloaddition of 3-acyloxy-1,4-enyne (ACE) and CO: A computational study. Chinese Chemical Letters. 2015 ;26:730-734.
Schienebeck CM, Song WZ, Smits AM, Tang WP. Rhodium-Catalyzed Intermolecular 5+1 and 5+2 Cycloadditions Using 1,4-Enynes with an Electron-Donating Ester on the 3-Position. Synthesis-Stuttgart. 2015 ;47:1076-1084.
Shu XZ, Schienebeck CM, Li XX, Zhou X, Song WZ, Chen LQ, Guzei IA, Tang WP. Rhodium-Catalyzed Stereoselective Intramolecular 5+2 Cycloaddition of 3-Acyloxy 1,4-Enyne and Alkene. Organic Letters. 2015 ;17:5128-5131.

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