All Faculty and Research Staff Publications

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Gold B, Aronoff MR, Raines RT. 1,3-Dipolar Cycloaddition with Diazo Groups: Noncovalent Interactions Overwhelm Strain. Organic Letters. 2016 ;18:4466-4469.
Aronoff MR, Gold B, Raines RT. 1,3-Dipolar Cycloadditions of Diazo Compounds in the Presence of Azides. Organic Letters. 2016 ;18:1538-1541.
Chattopadhyay S, Guthrie KM, Teixeira L, Murphy CJ, Dubielzig RR, McAnulty JF, Raines RT. Anchoring a cytoactive factor in a wound bed promotes healing. Journal of Tissue Engineering and Regenerative Medicine. 2016 ;10:1012-1020.
Gold B, Aronoff MR, Raines RT. Decreasing Distortion Energies without Strain: Diazo-Selective 1,3-Dipolar Cycloadditions. Journal of Organic Chemistry. 2016 ;81:5998-6006.
Mix KA, Aronoff MR, Raines RT. Diazo Compounds: Versatile Tools for Chemical Biology. ACS Chemical Biology. 2016 ;11:3233-3244.
Thomas SP, Kim E, Kim JS, Raines RT. Knockout of the Ribonuclease Inhibitor Gene Leaves Human Cells Vulnerable to Secretory Ribonucleases. Biochemistry. 2016 ;55:6359-6362.
Newberry RW, Orke SJ, Raines RT. n ->pi* Interactions Are Competitive with Hydrogen Bonds. Organic Letters. 2016 ;18:3614-3617.
Tanrikulu IC, Forticaux A, Jin S, Raines RT. Peptide tessellation yields micrometre-scale collagen triple helices. Nature Chemistry. 2016 ;8:1008-1014.
Johnston SB, Raines RT. PTENpred: A Designer Protein Impact Predictor for PTEN-related Disorders. Journal of Computational Biology. 2016 ;23:969-975.
Aronoff MR, Gold B, Raines RT. Rapid cycloaddition of a diazo group with an unstrained dipolarophile. Tetrahedron Letters. 2016 ;57:2347-2350.
Arnold U, Raines RT. Replacing a single atom accelerates the folding of a protein and increases its thermostability. Organic & Biomolecular Chemistry. 2016 ;14:6780-6785.
Vasta JD, Andersen KA, Deck KM, Nizzi CP, Eisenstein RS, Raines RT. Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells. ACS Chemical Biology. 2016 ;11:193-199.
Choudhary A, Kamer KJ, Shoulders MD, Raines RT. 4-Ketoproline: An Electrophilic Proline Analog for Bioconjugation. Biopolymers. 2015 ;104:110-115.
Checco JW, Lee EF, Evangelista M, Sleebs NJ, Rogers K, Pettikiriarachchi A, Kershaw NJ, Eddinger GA, Belair DG, Wilson JL, et al. alpha/beta-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells. Journal of the American Chemical Society. 2015 ;137:11365-11375.
Tonelli M, Eller CH, Singarapu KK, Lee W, Bahrami A, Westler WM, Raines RT, Markley JL. Assignments of RNase A by ADAPT-NMR and enhancer. Biomolecular NMR Assignments. 2015 ;9:81-88.
Caes BR, Teixeira RE, Knapp KG, Raines RT. Biomass to Furanics: Renewable Routes to Chemicals and Fuels. Acs Sustainable Chemistry & Engineering. 2015 ;3:2591-2605.
Johnston SB, Raines RT. Catalysis by the Tumor-Suppressor Enzymes PTEN and PTEN-L. Plos One. 2015 ;10.
Desai KK, Beltrame AL, Raines RT. Coevolution of RtcB and Archease created a multiple-turnover RNA ligase. RNA. 2015 ;21:1866-1872.
Johnston SB, Raines RT. Conformational Stability and Catalytic Activity of PTEN Variants Linked to Cancers and Autism Spectrum Disorders. Biochemistry. 2015 ;54:1576-1582.
Ellison AJ, Van Veller B, Raines RT. Convenient synthesis of collagen-related tripeptides for segment condensation. Biopolymers. 2015 ;104:674-681.
McGrath NA, Andersen KA, Davis AKF, Lomax JE, Raines RT. Diazo compounds for the bioreversible esterification of proteins. Chemical Science. 2015 ;6:752-755.
Andersen KA, Aronoff MR, McGrath NA, Raines RT. Diazo Groups Endure Metabolism and Enable Chemoselectivity in Cellulo. Journal of the American Chemical Society. 2015 ;137:2412-2415.
Marshall CJ, Grosskopf VA, Moehling TJ, Tillotson BJ, Wiepz GJ, Abbott NL, Raines RT, Shusta EV. An Evolved Mxe GyrA Intein for Enhanced Production of Fusion Proteins. ACS Chemical Biology. 2015 ;10:527-538.
Windsor IW, Raines RT. Fluorogenic Assay for Inhibitors of HIV-1 Protease with Sub-picomolar Affinity. Scientific Reports. 2015 ;5.
Andersen KA, Martin LJ, Prince JM, Raines RT. Intrinsic site-selectivity of ubiquitin dimer formation. Protein Science. 2015 ;24:182-189.
Mix KA, Raines RT. Optimized Diazo Scaffold for Protein Esterification. Organic Letters. 2015 ;17:2358-2361.
Vasta JD, Raines RT. Selective inhibition of prolyl 4-hydroxylases by bipyridinedicarboxylates. Bioorganic & Medicinal Chemistry. 2015 ;23:3081-3090.
Underkofler KA, Teixeira RE, Pietsch SA, Knapp KG, Raines RT. Separation of Lignin from Corn Stover Hydrolysate with Quantitative Recovery of Ionic Liquid. Acs Sustainable Chemistry & Engineering. 2015 ;3:606-613.
Porter DF, Koh YY, VanVeller B, Raines RT, Wickens M. Target selection by natural and redesigned PUF proteins. Proceedings of the National Academy of Sciences of the United States of America. 2015 ;112:15868-15873.
Newberry RW, VanVeller B, Raines RT. Thioamides in the collagen triple helix. Chemical Communications. 2015 ;51:9624-9627.
Eller CH, Yang GB, Ouerfelli O, Raines RT. Affinity of monoclonal antibodies for Globo-series glycans. Carbohydrate Research. 2014 ;397:1-6.
Eller CH, Lomax JE, Raines RT. Bovine Brain Ribonuclease Is the Functional Homolog of Human Ribonuclease 1. Journal of Biological Chemistry. 2014 ;289:25996-26006.
Lavis LD, Raines RT. Bright Building Blocks for Chemical Biology. ACS Chemical Biology. 2014 ;9:855-866.
Chattopadhyay S, Raines RT. Collagen-Based Biomaterials for Wound Healing. Biopolymers. 2014 ;101:821-833.
Zasadil LM, Andersen KA, Yeum D, Rocque GB, Wilke LG, Tevaarwerk AJ, Raines RT, Burkard ME, Weaver BA. Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles. Science Translational Medicine. 2014 ;6.
D'Avino C, Paciello R, Riccio G, Coppola M, Laccetti P, Maurea N, Raines RT, De Lorenzo C. Effects of a second-generation human anti-ErbB2 ImmunoRNase on trastuzumab-resistant tumors and cardiac cells. Protein Engineering Design & Selection. 2014 ;27:83-88.
Lomax JE, Bianchettl CM, Chang A, Phillips GN, Fox BG, Raines RT. Functional Evolution of Ribonuclease Inhibitor: Insights from Birds and Reptiles. Journal of Molecular Biology. 2014 ;426:3041-3056.
Newberry RW, Raines RT. A Key n ->pi* Interaction in N-Acyl Homoserine Lactones. ACS Chemical Biology. 2014 ;9:880-883.
Choudhary A, Newberry RW, Raines RT. n ->pi* Interactions Engender Chirality in Carbonyl Groups. Organic Letters. 2014 ;16:3421-3423.
Tanrikulu IC, Raines RT. Optimal Interstrand Bridges for Collagen-like Biomaterials. Journal of the American Chemical Society. 2014 ;136:13490-13493.
Lukesh JC, Andersen KA, Wallin KK, Raines RT. Organocatalysts of oxidative protein folding inspired by protein disulfide isomerase. Organic & Biomolecular Chemistry. 2014 ;12:8598-8602.
Lukesh JC, Wallin KK, Raines RT. Pyrazine-derived disulfide-reducing agent for chemical biology. Chemical Communications. 2014 ;50:9591-9594.
Newberry RW, Bartlett GJ, VanVeller B, Woolfson DN, Raines RT. Signatures of n ->pi* interactions in proteins. Protein Science. 2014 ;23:284-288.
Bingman CA, Cheng CL, Phillips GN, Raines RT. Structure of RNA 3 '-phosphate cyclase bound to substrate RNA AU Desai, KK Bingman, CA Cheng, CL Phillips, GN Raines, RT. RNA-a Publication of the RNA Society. 2014 ;20:1560-1566.
Desai KK, Cheng CL, Bingman CA, Phillips GN, Raines RT. A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation. Nucleic Acids Research. 2014 ;42:3931-3942.