Chemistry Newsletter - 06/07/1999

University of Wisconsin-Madison Department of Chemistry Newsletter

Organic Chemistry Cumulative Exam Schedule, 1999.

Thursdays, 7:30 p.m., room B371 Chemistry Building.

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ATTENTION GRADUATE STUDENTS

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IMPORTANT DATES:

MINOR AGREEMENT FORMS: The Graduate School requires that the minor program be outlined in an agreement which is approved by the Department no later than halfway through completion of the sequence of minor courses. The minor requirement is expected to be completed by the end of the third year of graduate school. Minor agreement forms are available in Room 1221.

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SEMINARS

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None available for this Newsletter.

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Recent Publications

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Penn RL; Banfield JF

Formation of rutile nuclei at anatase {112} twin interfaces and the phase transformation mechanism in nanocrystalline titania.

AMERICAN MINERALOGIST 1999, Vol 84, Iss 5-6, pp 871-876.

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Copyright � 1999 Institute for Scientific Information

For Industrial Positions, see the Chemistry Placement Newsletter at:

http://www.chem.wisc.edu/placement/7news.html

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FACULTY POSITIONS/TEMPORARY FACULTY/ACADEMIC POSITIONS

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Department of Chemistry, The University of Queensland, Australia. Chair of Biological Chemistry. Applications are invited for the position of Professor of Chemistry, in the field of biological chemistry, in the Department of Chemistry at The University of Queensland. The Department has strong research programs across a wide spectrum of contemporary chemistry and links with many physical sciences, biological sciences and engineering departments. The current $100 million development of the Institute of Molecular Biosciences and the establishment of a Centre for Marine Studies offer exciting possibilities for research in biological chemistry. Staff have access to excellent instrumental facilities, within the Department and elsewhere in the University, to mechanical, electronic and glassblowing workshops, and to first-class library resources. The appointee to the Chair will be a distinguished chemist with vigorous current research activity based on an outstanding record of scientific achievement in biological chemistry. Applications are encouraged in any facet of this wide-ranging field. The University is interested in exploring possibilities that focus on chemical synthesis, bioorganic chemistry and molecular design of biomimetics, and their interaction with biological targets. A strong commitment to teaching and curriculum design at all levels is essential. The successful applicant will be expected to assume the Headship of the Department for a period of five years in the first instance. Skills in personnel and financial management are essential. The appointee will be responsible for providing academic leadership to the Department, requiring a clear insight into the broader discipline of chemistry and the ability to represent the Department strongly in the Faculty, in the wider University, the profession and the community. A capacity to generate new sources of income, based on the research strengths of the Department, is also an important criterion of selection. The salary for a Professor is $91,821 per annum. A salary loading for the Headship of the Department also applies. Further information about the position, including selection criteria and duty statement, may be obtained from Professor John de Jersey, Head, School of Molecular and Microbial Sciences, on telephone +61 7 3365-4622, fax +61 7 3365-4699, email dejersey@biosci.uq.edu.au or from Associate Professor John Cotton, Head, Department of Chemistry, on telephone +61 7 3365-3837, fax +61 7 3365-4273, or email cotton@chemistry.uq.edu.au. General information about the Department can be obtained through http://www.chemistry.uq.edu.au. Send four copies of your application to: the Personnel Officer, Faculty of Biological and Chemical Sciences, The University of Queensland, Brisbane, Qld, 4072. Please quote Reference No. 28399, address the selection criteria, and include the names and contact details (fax and email) of three referees. Closing date for applications: 30 July 1999.

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The Chemistry Department at Wichita State University seeks applications for a tenure eligible position at the assistant professor level. Chemists with experience in mass spectrometry instrumentation are sought for Fall of 1999 or Spring of 2000. Funds are available for a new mass spectrometer. The individual will teach in the Analytical Chemistry Division at the Ph.D., M.S. and B.S. levels and is expected to obtain external funding for his/her research program. Start-up funding is available for supplies, equipment and support of personnel. A Ph.D. degree with additional training at the postdoctoral level is required. Letters of recommendation, future research plans, publication record, teaching interests, experience in mass spectrometry instrumentation and successful experience with diverse populations will be used to evaluate qualifications for this position. Applicants must submit a letter of application which delineates their qualifications for the position, curriculum vitae including publication record, description of future research plans, teaching interests, and three letters of recommendation to: Prof. W. Robert Carper, Chair of Search Committee, Department of Chemistry, Wichita State University, Wichita, KS 67260-0051, Tel: (316) 978-3120; Fax: (316) 978-3431; e-mail: carper@wsuhb.uc.twsu.edu . Screening will commence May 15, 1999 and continue until the position is filled. Departmental web site: http://www.mrc.twsu.edu/chemistry .

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Grand Valley State University. Assistant Professor of Chemistry. This is a one year, visiting appointment. Ph.D. in organic chemistry. A strong commitment to undergraduate teaching. Teach lecture and laboratory courses in organic chemistry and be actively involved in departmental service. Chemistry Department/Science and Mathematics Division. Send letter of application, complete resume, a statement of teaching philosophy, and three letters of reference to: Dr. Harvey Nikkel, Chair Department of Chemistry 327 Padnos Hall Grand Valley State University Allendale, MI 49401, e-mail: nikkelh@gvsu.edu .

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Marquette University, Laboratory Supervisor. (Full-Time, 10-Month Position). Manage and supervise the teaching assistants associated with the organic laboratories (chemistry 023, 024, 123, and 124). Responsible for the organization and quality of the lab instruction. Meet with the teaching assistants on a regular basis to insure quality of instruction, including the pre-lab lectures and actual running of the lab. Present pre-lab lectures to several labs in joint sessions; insure the safe handling of chemicals and disposal of waste; and assist and supervise the grading and exams. Manage the operation and use of the instruments associated with this lab (nmr, infrared, ge's, uv, and mass spec.) and participate in developing new laboratory experiments (computational, instrumental, and "wet"). Requires a master's degree in organic chemistry, doctorate preferred. Must possess prior management and teaching experience. Postdoctoral experience and knowledge of computers, molecular mechanics and chemical modeling, and instrumentation (gc-ms and nmr) a definite plus. Position available, August 15^th, 1999. Application deadline is July 15^th, 1999. Interested individuals please send a letter of interest, resume and at least two letters of recommendation to: Professor Charles A. Wilkie, Department of Chemistry, Marquette University, P.O. Box 1881, Milwaukee, WI 53201-1881, Phone: (414) 288-7239, Fax: (414) 288-7066.

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A Scientist to join a multidisciplinary team focused on the discovery of central and peripheral targets involved in obesity, appetite control, wasting disorders, and in the discovery of small molecular weight compounds that can be used to modulate these conditions in humans. The qualified scientist will be responsible for the discovery of novel targets useful for the treatment of human obesity and wasting disorders, establish high-throughput screening assays with these targets, and assist in the identification of drug candidates. The qualified candidate should possess a Ph.D. in Biochemistry or a related discipline and at least 2 years post doctoral experience. Expertise in peripheral mechanisms of obesity, adipogenesis, and fatty acid/lipid metabolism would be a plus. Our client is a leading pharmaceutical company with research facilities in Connecticut and can provide excellent benefits (health insurance, dental and vision plan, paid vacation and more). A high impact, high profile position with excellent opportunity for advancement. Geographic Location of Position: US-CT. Contact: Brock Granite; Diedre Moire Corporation; Voice: 609-584-9000 ext 235; Fax: 609-584-9575; Email: 915613@candseek.com.

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Seeking a Scientist who will lead a department of Analytical Chemistry. The department develops and implements analytical technology in support of Research, including large and small molecule mass spectrometry, NMR spectroscopy, separations, optical spectroscopy, protein sequencing and characterization of post-translational modifications and proteomics. The candidate will be responsible for performance planning, employee development and performance reviews of department members. This person will also make recommendations about capital equipment and staffing levels for the department. The candidate will possess a Ph.D. in Analytical Chemistry, Chemistry, Biochemistry or related field with relevant pharmaceutical or bio-tech experience. This person should posses strong leadership, interpersonal, verbal and written communication skills and be capable of directing the work of a staff in a wide range of scientific expertise. Our client is a leading pharmaceutical firm with research facilities in North Carolina and can provide excellent benefits (health insurance, dental, and vision plan, paid vacation and more). A high impact, high profile position with excellent opportunity for advancement. Geographic Location of Position: US-NC. Contact: Shane Smith; DMC; Voice: 609-584-9000 ext 218; Fax: 609-584-9575; Email: 915608@candseek.com.

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POSTDOCTORAL POSITION AND/OR JOBS

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Assistant Professor Paul Cornillon of Purdue University is currently seeking a PhD student to work in the area of freezing of foods. He/she must have a MS degree in Food Science, Food Engineering, Chemical Engineering or closely related field with a GPA of 3.25 or higher. The research topic is to improve the shelf-life stability of frozen foods by understanding 1) the quality changes in color and nutrient content, 2) the changes in water mobility and 3) the crystallization mechanism of water into ice. A previous experience working on freezing of foods is a plus. Knowledge of all or some of the following analytical tools is highly desirable: nuclear magnetic resonance spectroscopy, magnetic resonance imaging, differential scanning calorimetry, ultrasonic methods. Please forward your resume to me (<mailto:cornillo@purdue.edu>cornillo@purdue.edu) by email as soon as possible. This position is to start September 1, 1999. Send info to: Paul Cornillon, Assistant Professor, Purdue University, Whistler Center for Carbohydrate Research, Department of Food Science, 1160 Food Science Building, West Lafayette, IN 47907-1160, (USA), Tel: +1-765-494-1749 Fax: +1-765-494-7953, Email: cornillo@foodsci.purdue.edu .

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Department of Chemistry, University of Michigan. Postdoctoral Research Fellowship. Enzymology of Free Radical Reactions. An NIH-funded postdoctoral position is available to study how enzymes generate and control reactive free radical species to catalyze chemically difficult reactions. We are using protein engineering, combined with a variety of physical and kinetic techniques to dissect the mechanism of coenzyme B₁₂-dependent glutamate mutase. The unusual isomerization of L-glutamate to L-threo-3-methylaspartate catalyzed by this enzyme serves as a model system with which to investigate the phenomenon of radical-mediated enzyme catalysis. Candidates for this position should have experience in the purification of recombinant proteins from E. colt; steady state enzyme kinetics, and preferably pre-steady state enzyme kinetics. Experience in one or more of the following areas would be also an advantage: sitedirected mutagenesis; synthesis of isotopically-labeled compounds; microcalorimetry; NMR spectroscopy. Applicants should send their c.v. and the names, addresses and telephone numbers of three references to Dr. Neil Marsh at: Dr. Neil Marsh Department of Chemistry University of Michigan 940 N. University Ave. Ann Arbor MI 48109-1055, Tel: (734) 763-6096 e-mail: nmarsh@umich.edu , http://www.umich.edu/~michchem . Informal inquires are welcome by phone or e-mail.

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Postdoctoral Research Fellowship, University of Michigan, Department of Chemistry. Parke-Davis, Pharmaceutical Research. The University of Michigan and Parke-Davis Pharmaceutical Research have created an innovative partnership for postdoctoral training in chemical biology. These prestigious fellowships are funded by Parke-Davis to support collaborative research between Parke-Davis and the University. The appointment is for two years and carries a stipend of up to $ 30,000 p.a. and health care benefits. This newly-initiated project aims to examine how the "fluorous effect" - novel non-covalent interactions that arise when aliphatic or aromatic groups are perfluorinated - may be exploited in drug design. The incorporation of fluorocarbons into a drug may potentially increase its specificity and big-availability The project will initially examine the effect on binding and specificity of incorporating perfluorinated sidechains into inhibitors of matrix metallo-proteinases, a class of proteases that have been implicated in the spread of cancer. Candidates for this position should have experience in organic synthesis; experience in organo-fluorine chemistry or peptide synthesis would be a particular advantage. Experience in the characterization of ligand-receptor binding interactions is also desirable. The project is co-mentored by Dr. Peter Toogood (Parke-Davis) and Dr. Neil Marsh (University of Michigan). Applicants should send their c.v. and the names, addresses and telephone numbers of three references to: Dr. Neil Marsh, Department of Chemistry, University of Michigan, 940 N. University Ave., Ann Arbor MI 48109-1055, Tel: (734) 763-6096, http://www.umich.edu/~michchem . Informal inquires are welcome by phone or e-mail: Dr. Neil Marsh (University of Michigan) nmarsh@umich.edu or to Dr. Peter Toogood (Parke-Davis) Peter.Toogood@wl.com .

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Please submit all newsletter information or address changes to: goldade@chem.wisc.edu or 262-0293. Thank You.

DETAILS ARE AVAILABLE IN ROOM 1380.

NEXT NEWSLETTER IS ON JUNE 21^st, 1999.