Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(II) macrocycle

TitleSynthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(II) macrocycle
Publication TypeJournal Article
Year of Publication2008
AuthorsTseng, TSA, Burstyn, JN
JournalChemical Communications
Pagination6209-6211
Accession NumberISI:000261742100037
KeywordsChemistry, Multidisciplinary
Abstract

An intercalator-linked macrocycle 3,6-bis(dimethylamino)-10-(6-[1,4,7-triazacyclononane] hexyl) acridinium bromide was synthesized, its copper(II) complex was prepared, and the DNA cleavage activity of this metal complex was compared to that of the intercalator-free (Cu[9] aneN(3))(2+) complex.

Short TitleChem. Commun