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Rapid release of plasmid DNA from polyelectrolyte multilayers: A weak poly(acid) approach
Tue, 11/27/2012 - 11:44am — root
| Title | Rapid release of plasmid DNA from polyelectrolyte multilayers: A weak poly(acid) approach |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Flessner, RM, Yu, Y, Lynn, DM |
| Journal | Chemical Communications |
| Volume | 47 |
| Pagination | 550-552 |
| Accession Number | ISI:000285068300137 |
| Keywords | anionic polyelectrolytes, biomedical applications, Chemistry, Multidisciplinary, degradable polyamines, delivery, erosion, layers, membranes, physiological conditions, polymer-films, thin-films |
| Abstract | We demonstrate an approach to the assembly of DNA-containing polyelectrolyte multilayers that can be used to promote rapid release of DNA from surfaces. The approach is based on layer-by-layer incorporation of poly(acrylic acid) to promote rapid erosion in physiologically relevant media. |
| Short Title | Chem. Commun |
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