Chemoselective silver-catalyzed nitrene insertion reactions

TitleChemoselective silver-catalyzed nitrene insertion reactions
Publication TypeJournal Article
Year of Publication2014
AuthorsScamp, RJ, Rigoli, JW, Schomaker, JM
JournalPure and Applied Chemistry
Volume86
Pagination381-393
ISBN Number0033-4545
Keywordsaziridines, catalysis, coordination chemistry, C–h Bond Reactivity, Homogeneous catalysis, Omcos-17, silver
Abstract

A review of recent developments in silver(I)-catalyzed nitrene insertions into olefin and C–H bonds is presented, with a particular emphasis on reactions where the chemoselectivity can be tuned to promote either aziridination or C–H amination. The scope and synthetic utility of various silver catalysts are described, as well as preliminary investigations into the mechanisms of silver-catalyzed aminations.