image

Total synthesis of Wodeshiol:
Reference: Han, X.; Corey, E. J. Org. Lett. 1999, 1, 1871–1872. DOI
Keywords: Enone → Allyl-OH(asym) • Enone → Enone-α-Halo • Li/I → Li-Vinyl • Li-Vinyl → Sn-Vinyl • Sn-Vinyl oxidative coupling • Pd/Sn-Vinyl+Vinyl-X • Epoxidation, V • Epoxide → Tetrahydrofuran • Ether-5 •
Reagents: Bromine • NEt3 • Corey oxazaborolidine • BH(Catechol) • BuLi(tert) • SnBu3-Cl • Pd(PPh3)4 • CuCl • CuCl2 • VO(acac)2 • Hydroperoxide, tbutyl • TsOH·Py •

Syntheses Home