| Reference: | Büchi, G.; Matsumoto, K. E.; Nishimura, H. J. Am. Chem. Soc. 1971, 93, 3299. DOI |
| Keywords: | N-H -> N-C(O)R • N-C(O)R -> N-H • Amine-6 • Ketone -> Alkyl-OH • O-H -> O-C(O)R • ConjAdd Amine • ConjAdd Amine • Aldol-Na -> Aldol • Ketone enolate+Aldehyde • Amine-6 • Ketone enolate+Alkyl-X • Deconjugative alkylation • Claisen acylation, carbonate • CarboxEster enolate+Carbonate • CarboxEster -> CarboxEster-α-OH • ConjAdd Enamine • Amine-5 • |
| Reagents: | Methyl chlorovinyl ketone • NEt3 • Acetic anhydride, NEt3 • HCl • Acrolein • NaOMe • BF3 • KOtBu • O=C(OR)2 • NaH • KOtBu • H2O2 • AlH4-Li+ • Acetic anhydride • BF3 • |