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Total synthesis of Thujopsene:
Reference: Dauben, W. G.; Ashcraft, A. C J. Am. Chem. Soc. 1963, 85, 3673. DOI
Keywords: Simmons-Smith • Enone enolate+Alkyl-X • Deconjugative alkylation • Alkyl-X+Enolate • Wolff-Kishner • Ketone → CH2 • Allylic oxidation → Enone • Enone → Allyl-OH • Alkyl-OH → Ketone • Mg-Alkyl+Ketone • Ketone+Mg-Alkyl • Dehydration → Ene •
Reagents: MeI • KOtBu • Hydrazine • Hydroxide, potassium • CrO4Na2 • Acetic anhydride • AlH4-Li+ • CH2I2, Zn/Cu • CrO3, H2SO4 (Jones) • MeMgBr • Chloride, ammonium •

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