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Total synthesis of Strychnine:
Reference: Solé, D.; Bonjoch, J.; García-Rubio, S.; Peidró, E.; Bosch, J. Chem. Eur. J. 2000, 6, 655. DOI
Keywords: Ozonolysis • Ketone → EnolSilane • N-C(O)OR → N-Me • Lactam-6 • Ketone-1,3-di enolate+Aryl-X • Ketone-1,3-di enolate+Alkyl-X • Alkyl-X+Enolate • Reductive amination, asym • Amine-5 • N-Bn → N-C(O)OR • EnolSilane → Ketone-α-SeR • Selenoxide-Ei → Enone • N-H → N-Alkyl • Pd-Heck reductive • Ketone enolate+Mander • Nitro → Amine • Reductive amination, Zn • Indole synthesis • CarboxEster epimerization • CarboxEster → Aldehyde • Mechanism • Ether-7 • Knoevenagel condensation •
Reagents: Carbonate, potassium • Allyl-Br • Carbonate, potassium • BH3CN-Na+ • NH(SiMe3)2 (HMDS) • SePh-Cl • NHiPr2 • Iodide, lithium • Pd(OAc)2 • NEt3 • LiN(SiMe3)2 • HMPA (solvent) • O=C(OR)CN • H2SO4 • NaH • AlHiBu2 • Malonic acid • Acetate, sodium •

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