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Total synthesis of Sparteine:
Reference: Smith, B. T.; Wendt, J. A.; Aube, J. Org. Lett. 2002, 4, 2577. DOI
Keywords: Alkyl-OH → Ketone • Ketone → Ketal • CarboxAmide → Thioamide • N-Boc → N-H • Photochemistry • Aldol-Li → Enone • Ketone enolate+Alkyl-X, Intram • Alkyl-X+Enolate • Hydrogenation alkene • Enone → Ketone • Mitsunobu → Azide • Alkyl-OH → Alkyl-N3 • Nitrone → Oxaziridine • Pd-Hydrosilylation • CarboxAmide → Amine • CarboxAmide → Amine • CompE+-CarboxAmide/Ketone+Lawesson • Si-Alkyl → HO-Alkyl • N-H → N-Alkyl • Alkyl-X → Alkyl-I • Finkelstein reaction • Lactam-7 • Amine-6 • Schmidt reaction • Lactam-7 • Amine-6 • Ketone → Nitrone •
Reagents: H2O2 • DMSO, (COCl)2 (Swern) • Glycol • LiNiPr2 • Sulfonyl chloride, methane • H2, Pd • Azide, zinc • PPh3, DEAD • Lawesson • RaNi • LiNiPr2 • Iodide, sodium • NHBoc2 • Carbonate, potassium • Acetic acid • Bicarbonate, sodium • Photochemistry • AlH4-Li+ • PdCl(Allyl) • DBU • DMF (solvent) • TiCl4

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