image

Total synthesis of Solanopyrone:
Reference: Wilson, R. M.; Jen, W. S.; MacMillan, D. W. C. J. Am. Chem. Soc. 2005, 127, 11616. DOI
Keywords: Alkyl-OH → Ketone-1,3-di • Lactone-6 • Li/H → Li-Pyrone • Diels-Alder, Intram(asym) • Mukaiyama Aldol • Aldol-Si • Ketene acetal+Aldehyde • Aldehyde+EnolSilane • Li-Vinyl+CarboxEster • Enol → EnolEther • Pyrone synthesis •
Reagents: Imidazolone • Chiral catalyst • Chiral catalyst • TiCl4 • Dess-Martin • DBU • MeOTs • Carbonate, potassium • LiNiPr2 • Formate, methyl • DMF (solvent) • Chiral catalyst •

Syntheses Home