| Reference: | Ma, G.; Nguyen, H.; Romo, D. Org. Lett. 2007, 9, 2143. DOI |
| Keywords: | N-H -> N-PMB • Fischer esterification • O-Bn -> O-H • Pfitzner-Moffat • Alkyl-OH -> Aldehyde-α-NR2 • N-PMB -> N-H • N-H -> N-PMB • Reductive amination, B-H • N-H -> N-Alkyl • Zn-Allyl+Aldehyde • Aldehyde+Zn-R • Felkin-Anh • CompE+-Aldehyde/Lactone+Zn-R • Lactone-4 • Lactam-5 • Ketene Cycloaddition • Mechanism • Lactam-5 • |
| Reagents: | Allyl-OH • Ketene dimer • Pd(PPh3)4 • H2, Pd • DMSO, carbodiimide • Formic acid • Allyl-ZnX • Ceric ammonium nitrate • BH4-Na+ • NEtiPr2 • Pyridinium, 2-halo • DMAP • |