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Total synthesis of Ryanodine New:
Reference: Xu, C.; Han, A.; Virgil, S.C.; Reisman, S. E. ACS Cent. Sci. 2017, 3, 278-282. DOI
Keywords: Boronate ester → Diol-1,2 • O-BOM → O-H • O-H → O-C(O)R • Diol-1,2 → BoronateEster • Enone → Allyl-OH • CompRed-Ketone/CarboxEster+B-H • Hydrogenation Diene • Epoxidation, V • Radical cyclization(Alkyl) •
Reagents: BMe(OH)2 • BH4-Li+ • NaH • Bifluoride, potassium • H2, Pt • VO(acac)2 • Hydroperoxide, tbutyl • LiDBB •

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