| Reference: | Liras, S.; Lynch, C. L.; Fryer, A. M.; Vu, B. T.; Martin, S. F. J. Am. Chem. Soc 2001, 123, 5918. DOI |
| Keywords: | N-H -> N-Cbz • N-Cbz -> N-H • Pd/Sn-Aryl+Aryl-X • Stille coupling • N-H -> N-Me • Mannich • Alkyl-OH -> Alkyl-CN • Nitrile -> Imine • Lactone-5 • Mannich, vinylogous • Lactone-5 • |
| Reagents: | CH2=NMe2+I- • Cyanide, potassium • Carbonate, potassium • Boc2O • Aryl-SnR3 • Cbz-Succinimide • MeI • Carbonate, cesium • H2, Pd • DMAP • Formaldehyde • DMF (solvent) • DMF (solvent) • AlHiBu2 • |