Reaction scheme for total synthesis of the natural product Roflamycoin (Part 2)

Total synthesis of Roflamycoin (Part 2):

Reference:	Rychnovsky, S. D.; Khire, U. R.; Yang, G. J. Am. Chem. Soc. 1997, 119, 2058. DOI
Keywords:	O-SiMe₂^tBu -> O-H • Alkyl-OH -> Alkyl-I • Li-Nitrile+Alkyl-X • CarboxAcid -> CarboxEster • Alkyl-OH -> Aldehyde • Ketal -> Diol • Alkyl-CN -> Alkyl-H • O-Bn -> O-H • Li-Nitrile+Alkyl-X • Enolether -> Enal • HWE -> EnoateEster • Diol-1,2 cleavage • Li/Sn -> Li-Vinyl • Li-Vinyl -> Mg-Vinyl • Aldehyde+Li-Vinyl • Li-Vinyl+Aldehyde •
Reagents:	LiNEt₂ • DMPU (solvent) • Fluoride, Bu₄N⁺ • PPh₃, I₂ • LiNEt₂ • DMPU (solvent) • Li°/NH₃ • P(O)(OR)₂CHMe-C(O)OR • BOP • Dess-Martin • MeSO₂Cl, NEt₃ • DBU • Dowex • Periodate, sodium • Butadiene, 1-SnR₃ • Butadiene, 1-OR • BuLi(n) • MgBr₂ •