Reference: | Tufariello, J. J.; Lee, G. E. J. Am. Chem. Soc. 1980, 102, 373. DOI |
Keywords: | Ketone → Ketal(Me) N-R → N-OH Hydroxylamine → Nitrone O-H → O-SO2R Ketal → Ketone Ketone → Alkyl-OH EnoateEster → Allyl-OH Hydrogenolysis N-O Amine-5 N-H → N-Alkyl Dehydration → Enoate Cope elimination CompRed-Ketone/CarboxEster+B-H Nitrone Cycloaddition |
Reagents: | Orthoformate HCl, MeOH HgO Sulfonyl chloride, methane, NEt3 H2, Pd Sulfonyl chloride, methane NEt3 HCl, H2O BH4-Na+ AlH3 |