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Total synthesis of Pseudopterosin:
Reference: Newton, C. G.; Drew, S. L.; Lawrence, A. L.; Willis, A. C.; Paddon-Row, M. L.; Sherburn, M. S. Nature Chem. 2015, 7, 82–86. DOI
Keywords: O-H → O-SO2R • Nef reaction • Nitro → Aldehyde/Ketone • Diels-Alder, Enal • Diels-Alder, Enal • Diels-Alder, Allene • Diels-Alder, Nitro • Wittig-isopropyl • Pd-Sonogashira • Kumada coupling • Pd/Mg-Vinyl+Propargyl-X • Decarbonylation • Ketone → Ketone-α-OR • Ketone enolate+(Ox) • Ketone-α-OH → Ketone-1,2-di • Ketone-1,2-di •
Reagents: Sulfonyl chloride, methane, NEt3 • Ni(dppp)Cl2 • PPh3 • Propenyl-MgX • Acrolein • Rh(PPh3)3Cl • AlHiBu2 • BuLi(n) • PPh3=CMe2 • KOtBu • KN(SiMe3)2 • Oxaziridine • DMSO, (COCl)2 (Swern) • Pd(PPh3)4 • CuI • Dioxirane •

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