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Total synthesis of 15-Deoxy-Prostaglandin E1:
Reference: Sih, C. J.; Salomon, R. G.; Price, P.; Peruzzoti, G.; Sood, R. Chem. Commun. 1972, 240 DOI
Keywords: O-H → O-THP • O-H → O-THP • O-THP → O-H • Jones oxidation • Allyl-OH → Enone • ConjAdd Cu-R • Cu-Vinyl+Enone • Li-Cyclopentadienide+Alkyl-X • Alkyl-X+Li-R • Singlet oxygen+Diene •
Reagents: Cyclopentadienide • H2O2 • DHP • Vinyl-Li • CuI·PBu3 • Acetic acid • Baker's yeast • Al(OiPr)3 • CrO3, H2SO4 (Jones) • Hypochlorite, sodium • O2 (singlet) •

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