image

Total synthesis of Prephenate, disodium:
Reference: Danishefsky, S.; Hirama, M. J. Am. Chem. Soc. 1977, 99, 7740. DOI
Keywords: Sulfoxide-Ei → Enone • Ketone → Enone • Diels-Alder, EneSulfoxide • Enone → Allyl-OH • CompRed-Enone/Lactone+M-H • Lactone-5 • Sulfide → Sulfoxide • CarboxEster → CarboxAcid •
Reagents: HCl • Diazomethane • Perbenzoic acid, 3-chloro • BH-BBN • Hydroxide, sodium • Butadiene, 2-OR • Butadiene, 1-OR • Danishefsky diene •

Syntheses Home