image

Total synthesis of Platensimycin:
Reference: Zou, Y.; Chen, C.-H.; Taylor, C. D.; Foxman, B. M.; Snider, B. B. Org. Lett. 2007, 9, 1825. DOI
Keywords: Birch alkylation • Enone enolate+Alkyl-X • Alkyl-X+Enolate • Radical cyclization(Vinyl) • Ketone → Alkyl-OH • Alkene hydration • Dehydration → Ene • Allylic oxidation → Allyl-OH • Allyl-OH → Enone •
Reagents: Bromide, lithium • HCl, H2O • Allyl-Br • HSnBu3 • AIBN • Tf2O • Acetic acid, trifluoro • SeO2 • Microwave • MnO2

Syntheses Home