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Total synthesis of Phenserine:
Reference: Rigby, J. H.; Sidique,S. Org. Lett. 2007, 9, 1219 DOI
Keywords: Japp-Klingemann • Imine → Amine • N-H → N-Me • Ketal(thio) → CH2 • O-H → O-C(O)NR2 • Carbene Cycloaddition • Carbene, bisphenylthio • Lactam-5 • Curtius • C-CO2H → C-N • 1,1-Dipolarophile • CarboxAmide → Amine • N-H → N-Me • Fischer Indole • Indole synthesis •
Reagents: Nitrite, sodium • Hydroxide, potassium • HCl, EtOH • MeI • Hydroxide, lithium • Azide, diphenylphosphoryl • AlH4-Li+ • MeI • RaNi • AlH4-Li+ • B(Br)3 • Isocyanate • DMF (solvent) •

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