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Total synthesis of Vitamin B3:
Reference: Stiller, B. T.; Harris, S. A.; Finkelstein, J.; Keresztesy, J. C.; Folkers, K. J. Am. Chem. Soc. 1940, 112, 1785–1790. DOI
Keywords: HO- • Aldol-K → Aldol • Aldehyde enolate+Aldehyde • Aldehyde → Cyanohydrin • Nitrile → CarboxAcid • Lactone-5 • Lactone → Ester • CarboxEster → CarboxAcid •
Reagents: Formaldehyde • Carbonate, potassium • Cyanide, potassium • Chloride, calcium •

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