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Total synthesis of Deoxy-Pancratistatin:
Reference: Acena, J. L.; Arjona, O.; Leon, L.; Plumet, J. Org. Lett. 2000, 2, 3683-3686. DOI
Keywords: O-H → O-Tf • Alkene cleavage • Lactone-6 • Ketal → Diol-1,2 • EneSulfone epoxidation, nucleophilic • Hydrogenation azide • Azide → Amine • Alkyl-OH → Alkyl-N3 • Alkyl-SO2R → Alkyl-H • Li-Aryl+EneSulfone • EneSulfone+Li-R • ConjAdd Li-R • Lactam-6 •
Reagents: Hydroperoxide, tbutyl • BuLi(n) • Na(Hg) • Tf2O • RuCl3 • H2, Pd • Acetic acid, trifluoro • Carbonate, potassium • Azide,R4N+ • Periodate, sodium • Vinyl-Sulfone • Aryl-Li • BuLi(n) •

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