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Total synthesis of Nootkatone:
Reference: Marshall, J. A.; Ruden, R. A.. J. Org. Chem. 1971, 36, 594. DOI
Keywords: Ketone -> Ketal • Epoxidation, peracid • Enone -> Ketal • CarboxEster -> Alkyl-OH • Alkyl-OH -> Aldehyde • Wittig-methyl • CompE+-Ketone/Enone+Wittig • Wittig-alkyl+Ketone • Dieckmann • CarboxEster enolate+CarboxEster • Pinacol • Wolff-Kishner • Ketone -> CH2 • Robinson annulation, ketoester • Ketoester enolate+Enone •
Reagents: Orthoformate • NaH • PPh3=CH-Me • Perbenzoic acid, 3-chloro • BF3·OEt2 • Carbonate, sodium • Glycol • TsOH • AlH4-Li+ • Carbodiimide • Hydrazine • PPh3=CH2 • KOtAm •

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