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Total synthesis of Linalyl oxide:
Reference: Rychnovsky, S. D.; Bartlett, P. A. J. Am. Chem. Soc. 1981, 103, 3963-3964. DOI
Keywords: Li-Vinyl+Aldehyde • Li-Me+Ketone • Ketone+Li-Alkyl • Li-Me+Ketone • Ketone+Li-Alkyl • Dehydrohalogenation → Allyl-OR • Claisen-Enol ether • Iodoetherification • Ether-5 • Mechanism •
Reagents: Vinyl-Li • MeLi • MeLi • I2 • KOtBu • I2 • KOtBu •

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