Reference: | Baker, S. R.; Clissoid, D. W.; McKillop, A. Tetrahedron Lett. 1988, 29, 991. DOI |
Keywords: | O-H → O-SO2R Wittig-alkyl → Ene-trans Wittig-allyl → Diene CompE+-Aldehyde/CarboxEster+Wittig Wittig-alkyl → Ene-cis CompE+-Aldehyde/CarboxEster+Wittig Hydrogenation alkene Acetal → Diol-1,3 Diol-1,2 → Epoxide Alkyl-OH → Aldehyde |
Reagents: | PPh3=CH-Alkyl BuLi(n) H2, Pd Sulfonyl chloride, methane, NEt3 HCl, MeOH PPh3=CH-Vinyl PPh3=CH-Alkyl BuLi(n) Carbonate, potassium CrO3·Py2 (Collins) DMSO (solvent) Diazomethane |