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Total synthesis of Juvabione:
Reference: Soldermann, N.; Velker, J.; Vallet, O.; Stoeckli-Evans, H.; Neier, R. Helv. Chim. Acta 2000, 83, 2266. DOI
Keywords: CarboxAcid → CarboxCl • CarboxAcid → CarboxCl • Arndt-Eistert • Fe/Mg-Alkyl+CarboxCl • CarboxCl+Mg-R • Alkene isomerization • Diazoketone • Diels-Alder, EnoateEster • Claisen-Ireland •
Reagents: KOtBu • NaN(SiMe3)2 • SiMe2tBu-Cl • Oxalyl chloride • Diazoketone • Ag(O2CCF3)2 • DBU • Oxalyl chloride • Crotonaldehyde • Butadiene, 1-OR • Alkyl-MgX • Fe(acac)3 • DMPU (solvent) • Diazomethane • Acrylate •

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