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Total synthesis of Ibogamine, dl:
Reference: Sallay, S. I. J. Am. Chem. Soc. 1967, 89, 6762-6763. DOI
Keywords: CompNu-Amine/Alcohol+RC(O)X • Ketone → Ketal • CompE+-Ketone/Ketone+glycol • Ketone → Oxime • Beckman rearrangement • Lactam-7 • Epoxidation, peracid • Epoxide reduction • Alkyl-OH → Ketone • Wittig-methyl • Hydroboration alkene • CompRed-Alkene/Carboxamide+M-H • CarboxAmide → Amine • Ketal → Ketone • N-H → N-Alkyl • Amine-6 • Bicyclo(222) • Fischer Indole • Indole synthesis •
Reagents: Glycol • NH2OH • TsCl, Py • Perbenzoic acid • AlH4-Li+ • PPh3 • BH3 • AlH4-Li+ • O=C(OR)Cl • TsCl • HBr • Acetic acid • Hydrazine, phenyl • CrO3·Py2 (Collins) •

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