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Total synthesis of Hirsutene :
Reference: Hudlicky, T.; Kutchan, T. M.; Wilson, S. R.; Mao, D. T. J. Am. Chem. Soc. 1980, 102, 6351. DOI
Keywords: CarboxAcid → CarboxCl • CarboxEster → CarboxAcid • Claisen-Johnson • 1,3-Sigmatropic • Wittig-methyl • Mg-Vinyl+Aldehyde • Enal+Mg-R • Cyclopropanation Diazoketone • Diazoketone • Alkene isomerization • CompRed-Alkene/Ketone+H2
Reagents: Orthoacetate • Hg(OAc)2 • Oxalyl chloride • Diazoethane • Diazoketone • Cu(acac)2 • RhCl3 • H2, Pt • PPh3=CH2 • Hydroxide, potassium • Vinyl-MgX •

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