image

Total synthesis of 2,7-Cyclo-Farnesol:
Reference: Coates, R. M.; Jin, A. Q. J. Org. Chem. 1997, 62, 7475. DOI
Keywords: Ketone → EnolPhosphate • CarboxEster → Alkyl-OH • Cu-Me+EnoateEster • ConjAdd-Elimination • Li/I → Li-Alkyl • Li-Alkyl+Ketone • Enone-β-OR+Li-R • Enone-β-OR → Enone • Stork-Danheiser • Cu-Me+Enone • Ketone enolate+Mander • ConjAdd-Acylation •
Reagents: Alkyl-Li • BuLi(tert) • P(O)(OR)2Cl • LiCuMe2 • AlH4-Li+ • NaH • LiCuMe2

Syntheses Home