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Total synthesis of Ethisolide:
Reference: Burke, S. D.; Pacofsky, G. J.; Piscopio, A. D. J. Org. Chem. 1992, 57, 2228-2235. DOI
Keywords: Lactone-5 • Sulfoxide-Ei -> EneLactone • Mitsunobu -> Ester • Allyl-OH -> Allyl-OAc • Lactone-5 • Lactone-5 • O-SEM -> O-H • CarboxAcid -> CarboxEster • ConjAdd M-SR • Claisen-Ireland •
Reagents: LiN(SiMe3)2 • SiMe3-Cl • PPh3, DEAD • Camphor sulfonic acid • Perbenzoic acid, 3-chloro • Carbonate, potassium • DBU • HF • BF3·OEt2 • Thiolate, phenyl • Diazomethane •

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