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Total synthesis of Laurencenone B:
Reference: White, D. E.; Stewart, I. C.; Grubbs, R. H.; Stoltz, B. M. J. Am. Chem. Soc. 2008, 130, 810–811. DOI
Keywords: Li-Me+Ketone • Enone-β-OR+Li-R • Ketone → Ketone-α-Halo • Ketone → Alkyl-OH • RCM → Ring-C • Ketone → EnolEther • ConjAdd Enolate • Enone enolate+Enone • Wittig-methyl • Ketone → EnolCarbonate • Pd-enolate allylation • Tsuji-Trost allylation • Stork-Danheiser •
Reagents: TsOH • LiNiPr2 • Methyl vinyl ketone • PPh3=CH2 • KOtBu • LiNiPr2 • TMEDA • O=C(OR)Cl • Grubbs-Hoveyda • MeLi • CeCl3 • HCl, H2O • Bromine • HBr • AlHiBu2 • Chiral catalyst • Pd(dmdba)2

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